| Full name: FAM161 centrosomal protein B | Alias Symbol: FLJ31697 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 145483 | HGNC ID: HGNC:19854 | Ensembl Gene: ENSG00000156050 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM161B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM161B | 145483 | 242608_x_at | -0.0763 | 0.9011 | |
| GSE26886 | FAM161B | 145483 | 242608_x_at | -0.0410 | 0.8644 | |
| GSE45670 | FAM161B | 145483 | 242608_x_at | 0.1241 | 0.2814 | |
| GSE53622 | FAM161B | 145483 | 42467 | -0.2183 | 0.0032 | |
| GSE53624 | FAM161B | 145483 | 42467 | -0.3523 | 0.0000 | |
| GSE63941 | FAM161B | 145483 | 242608_x_at | -0.6778 | 0.0181 | |
| GSE77861 | FAM161B | 145483 | 242608_x_at | 0.4658 | 0.2539 | |
| GSE97050 | FAM161B | 145483 | A_23_P365226 | -0.2266 | 0.5176 | |
| SRP007169 | FAM161B | 145483 | RNAseq | -0.9844 | 0.0330 | |
| SRP064894 | FAM161B | 145483 | RNAseq | -0.4236 | 0.0028 | |
| SRP133303 | FAM161B | 145483 | RNAseq | -0.5147 | 0.0003 | |
| SRP159526 | FAM161B | 145483 | RNAseq | -0.5174 | 0.0287 | |
| SRP193095 | FAM161B | 145483 | RNAseq | -0.4125 | 0.0004 | |
| SRP219564 | FAM161B | 145483 | RNAseq | -0.4335 | 0.3501 | |
| TCGA | FAM161B | 145483 | RNAseq | -0.4432 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM161B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM161B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM161B | 145483 | 8 | 2 | 20 | |
| GSE20123 | FAM161B | 145483 | 8 | 2 | 20 | |
| GSE43470 | FAM161B | 145483 | 8 | 3 | 32 | |
| GSE46452 | FAM161B | 145483 | 16 | 3 | 40 | |
| GSE47630 | FAM161B | 145483 | 11 | 8 | 21 | |
| GSE54993 | FAM161B | 145483 | 3 | 8 | 59 | |
| GSE54994 | FAM161B | 145483 | 19 | 4 | 30 | |
| GSE60625 | FAM161B | 145483 | 0 | 2 | 9 | |
| GSE74703 | FAM161B | 145483 | 7 | 3 | 26 | |
| GSE74704 | FAM161B | 145483 | 3 | 2 | 15 | |
| TCGA | FAM161B | 145483 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 53; Total Number of normals: 320.
Somatic mutations of FAM161B:
Generating mutation plots.
Highly correlated genes for FAM161B:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM161B | ALMS1 | 0.862838 | 4 | 0 | 4 |
| FAM161B | ZNF160 | 0.848574 | 5 | 0 | 5 |
| FAM161B | NKTR | 0.82908 | 4 | 0 | 4 |
| FAM161B | C9orf64 | 0.825628 | 6 | 0 | 6 |
| FAM161B | DDX59 | 0.821161 | 5 | 0 | 5 |
| FAM161B | HAUS2 | 0.816004 | 5 | 0 | 5 |
| FAM161B | DLGAP4 | 0.815862 | 6 | 0 | 6 |
| FAM161B | NAA15 | 0.813502 | 3 | 0 | 3 |
| FAM161B | SLC22A3 | 0.809091 | 5 | 0 | 5 |
| FAM161B | SLC35E1 | 0.807633 | 6 | 0 | 6 |
| FAM161B | MZT2B | 0.805631 | 6 | 0 | 6 |
| FAM161B | DIP2A | 0.804503 | 6 | 0 | 6 |
| FAM161B | RSF1 | 0.802191 | 3 | 0 | 3 |
| FAM161B | CMBL | 0.802 | 5 | 0 | 5 |
| FAM161B | ZNF638 | 0.800845 | 3 | 0 | 3 |
| FAM161B | FBXW12 | 0.794194 | 5 | 0 | 5 |
| FAM161B | ZNF611 | 0.790864 | 5 | 0 | 5 |
| FAM161B | ZNF721 | 0.777482 | 6 | 0 | 6 |
| FAM161B | PTPN4 | 0.771595 | 3 | 0 | 3 |
| FAM161B | GTF2H3 | 0.76834 | 5 | 0 | 5 |
For details and further investigation, click here
