| Full name: abhydrolase domain containing 1 | Alias Symbol: LABH1|FLJ36128 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 84696 | HGNC ID: HGNC:17553 | Ensembl Gene: ENSG00000143994 | OMIM ID: 612195 |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD1 | 84696 | 236461_at | -0.0300 | 0.9245 | |
| GSE26886 | ABHD1 | 84696 | 236461_at | 0.4089 | 0.0056 | |
| GSE45670 | ABHD1 | 84696 | 1560117_at | 0.0963 | 0.2358 | |
| GSE53622 | ABHD1 | 84696 | 60909 | 0.1994 | 0.0453 | |
| GSE53624 | ABHD1 | 84696 | 52168 | 0.4558 | 0.0000 | |
| GSE63941 | ABHD1 | 84696 | 1560117_at | 0.1429 | 0.3705 | |
| GSE77861 | ABHD1 | 84696 | 1560117_at | -0.0882 | 0.6513 | |
| GSE97050 | ABHD1 | 84696 | A_23_P17242 | 0.2861 | 0.2017 | |
| SRP133303 | ABHD1 | 84696 | RNAseq | -0.4490 | 0.1269 | |
| TCGA | ABHD1 | 84696 | RNAseq | 0.3683 | 0.3798 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD1 | 84696 | 11 | 2 | 17 | |
| GSE20123 | ABHD1 | 84696 | 11 | 2 | 17 | |
| GSE43470 | ABHD1 | 84696 | 3 | 1 | 39 | |
| GSE46452 | ABHD1 | 84696 | 3 | 4 | 52 | |
| GSE47630 | ABHD1 | 84696 | 8 | 0 | 32 | |
| GSE54993 | ABHD1 | 84696 | 0 | 6 | 64 | |
| GSE54994 | ABHD1 | 84696 | 10 | 0 | 43 | |
| GSE60625 | ABHD1 | 84696 | 0 | 3 | 8 | |
| GSE74703 | ABHD1 | 84696 | 3 | 0 | 33 | |
| GSE74704 | ABHD1 | 84696 | 9 | 1 | 10 | |
| TCGA | ABHD1 | 84696 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of ABHD1:
Generating mutation plots.
Highly correlated genes for ABHD1:
Showing top 20/131 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD1 | GGN | 0.756761 | 3 | 0 | 3 |
| ABHD1 | TRPM6 | 0.735251 | 3 | 0 | 3 |
| ABHD1 | THSD7A | 0.721659 | 3 | 0 | 3 |
| ABHD1 | IFNL2 | 0.716122 | 3 | 0 | 3 |
| ABHD1 | NME4 | 0.712431 | 3 | 0 | 3 |
| ABHD1 | DZIP1L | 0.707527 | 3 | 0 | 3 |
| ABHD1 | GPR3 | 0.706713 | 3 | 0 | 3 |
| ABHD1 | TAS2R4 | 0.70574 | 3 | 0 | 3 |
| ABHD1 | SCARB1 | 0.703395 | 3 | 0 | 3 |
| ABHD1 | DISC1 | 0.702279 | 3 | 0 | 3 |
| ABHD1 | EFCAB5 | 0.70151 | 3 | 0 | 3 |
| ABHD1 | LRRC23 | 0.701226 | 3 | 0 | 3 |
| ABHD1 | GLRA2 | 0.698841 | 3 | 0 | 3 |
| ABHD1 | KLRG1 | 0.694595 | 3 | 0 | 3 |
| ABHD1 | PDGFB | 0.694064 | 4 | 0 | 4 |
| ABHD1 | GGT5 | 0.689518 | 3 | 0 | 3 |
| ABHD1 | DPYSL5 | 0.689043 | 3 | 0 | 3 |
| ABHD1 | CLSTN2 | 0.681738 | 3 | 0 | 3 |
| ABHD1 | NOD1 | 0.6806 | 3 | 0 | 3 |
| ABHD1 | EDN1 | 0.676817 | 3 | 0 | 3 |
For details and further investigation, click here
