| Full name: cadherin 22 | Alias Symbol: dJ998H6.1 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 64405 | HGNC ID: HGNC:13251 | Ensembl Gene: ENSG00000149654 | OMIM ID: 609920 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH22 | 64405 | 1569679_at | -0.0657 | 0.7682 | |
| GSE20347 | CDH22 | 64405 | 215181_at | -0.3681 | 0.0000 | |
| GSE23400 | CDH22 | 64405 | 215181_at | -0.1298 | 0.0003 | |
| GSE26886 | CDH22 | 64405 | 1569679_at | -0.2902 | 0.0308 | |
| GSE29001 | CDH22 | 64405 | 215181_at | -0.2190 | 0.3749 | |
| GSE38129 | CDH22 | 64405 | 215181_at | -0.2431 | 0.0279 | |
| GSE45670 | CDH22 | 64405 | 215181_at | -0.1524 | 0.1679 | |
| GSE53622 | CDH22 | 64405 | 18512 | 0.2026 | 0.0071 | |
| GSE53624 | CDH22 | 64405 | 18512 | 0.0673 | 0.4721 | |
| GSE63941 | CDH22 | 64405 | 1569679_at | 0.1071 | 0.3901 | |
| GSE77861 | CDH22 | 64405 | 1569679_at | 0.0151 | 0.9140 | |
| GSE97050 | CDH22 | 64405 | A_23_P40192 | 0.0833 | 0.7150 | |
| SRP133303 | CDH22 | 64405 | RNAseq | -1.7418 | 0.0003 | |
| SRP159526 | CDH22 | 64405 | RNAseq | -3.3922 | 0.0004 | |
| TCGA | CDH22 | 64405 | RNAseq | -0.4150 | 0.5544 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CDH22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH22 | 64405 | 14 | 1 | 15 | |
| GSE20123 | CDH22 | 64405 | 14 | 1 | 15 | |
| GSE43470 | CDH22 | 64405 | 12 | 1 | 30 | |
| GSE46452 | CDH22 | 64405 | 29 | 0 | 30 | |
| GSE47630 | CDH22 | 64405 | 24 | 1 | 15 | |
| GSE54993 | CDH22 | 64405 | 0 | 17 | 53 | |
| GSE54994 | CDH22 | 64405 | 25 | 0 | 28 | |
| GSE60625 | CDH22 | 64405 | 0 | 0 | 11 | |
| GSE74703 | CDH22 | 64405 | 10 | 1 | 25 | |
| GSE74704 | CDH22 | 64405 | 10 | 0 | 10 | |
| TCGA | CDH22 | 64405 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of CDH22:
Generating mutation plots.
Highly correlated genes for CDH22:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH22 | STRC | 0.831859 | 3 | 0 | 3 |
| CDH22 | ANKDD1A | 0.826734 | 3 | 0 | 3 |
| CDH22 | DCDC1 | 0.819866 | 3 | 0 | 3 |
| CDH22 | SLC39A5 | 0.794053 | 4 | 0 | 3 |
| CDH22 | C2CD4D | 0.778031 | 3 | 0 | 3 |
| CDH22 | PLA2G2C | 0.774242 | 3 | 0 | 3 |
| CDH22 | PNPLA7 | 0.77282 | 3 | 0 | 3 |
| CDH22 | GPR152 | 0.768857 | 3 | 0 | 3 |
| CDH22 | LCE1D | 0.763316 | 3 | 0 | 3 |
| CDH22 | SPEF2 | 0.753779 | 3 | 0 | 3 |
| CDH22 | SPACA3 | 0.750519 | 4 | 0 | 3 |
| CDH22 | CCDC62 | 0.74868 | 3 | 0 | 3 |
| CDH22 | TSPAN10 | 0.747969 | 4 | 0 | 4 |
| CDH22 | PABPN1L | 0.745601 | 3 | 0 | 3 |
| CDH22 | OR4D6 | 0.744938 | 3 | 0 | 3 |
| CDH22 | PGLYRP2 | 0.743944 | 3 | 0 | 3 |
| CDH22 | LRRC43 | 0.738902 | 4 | 0 | 4 |
| CDH22 | C1QL2 | 0.738312 | 3 | 0 | 3 |
| CDH22 | LCN9 | 0.73555 | 3 | 0 | 3 |
| CDH22 | LINC00858 | 0.734989 | 3 | 0 | 3 |
For details and further investigation, click here
