| Full name: kelch like family member 17 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 339451 | HGNC ID: HGNC:24023 | Ensembl Gene: ENSG00000187961 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL17 | 339451 | 1555650_at | -0.1340 | 0.5610 | |
| GSE26886 | KLHL17 | 339451 | 229792_at | 0.2339 | 0.1004 | |
| GSE45670 | KLHL17 | 339451 | 1555650_at | 0.0248 | 0.8118 | |
| GSE53622 | KLHL17 | 339451 | 57354 | 0.4780 | 0.0000 | |
| GSE53624 | KLHL17 | 339451 | 57354 | 0.4169 | 0.0001 | |
| GSE63941 | KLHL17 | 339451 | 1555650_at | 0.3072 | 0.0181 | |
| GSE77861 | KLHL17 | 339451 | 1555650_at | -0.0780 | 0.4505 | |
| GSE97050 | KLHL17 | 339451 | A_33_P3422330 | 0.1620 | 0.5222 | |
| SRP064894 | KLHL17 | 339451 | RNAseq | 0.6965 | 0.0024 | |
| SRP133303 | KLHL17 | 339451 | RNAseq | 0.0824 | 0.7509 | |
| SRP159526 | KLHL17 | 339451 | RNAseq | 0.1050 | 0.8359 | |
| SRP193095 | KLHL17 | 339451 | RNAseq | 0.3478 | 0.0335 | |
| SRP219564 | KLHL17 | 339451 | RNAseq | 0.1821 | 0.6832 | |
| TCGA | KLHL17 | 339451 | RNAseq | 0.1901 | 0.0774 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHL17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL17 | 339451 | 3 | 7 | 20 | |
| GSE20123 | KLHL17 | 339451 | 3 | 6 | 21 | |
| GSE43470 | KLHL17 | 339451 | 1 | 5 | 37 | |
| GSE46452 | KLHL17 | 339451 | 7 | 1 | 51 | |
| GSE47630 | KLHL17 | 339451 | 8 | 4 | 28 | |
| GSE54993 | KLHL17 | 339451 | 2 | 2 | 66 | |
| GSE54994 | KLHL17 | 339451 | 15 | 2 | 36 | |
| GSE60625 | KLHL17 | 339451 | 0 | 0 | 11 | |
| GSE74703 | KLHL17 | 339451 | 1 | 3 | 32 | |
| GSE74704 | KLHL17 | 339451 | 3 | 0 | 17 | |
| TCGA | KLHL17 | 339451 | 14 | 20 | 62 |
Total number of gains: 57; Total number of losses: 50; Total Number of normals: 381.
Somatic mutations of KLHL17:
Generating mutation plots.
Highly correlated genes for KLHL17:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL17 | SLC26A5 | 0.767546 | 3 | 0 | 3 |
| KLHL17 | PCBP3 | 0.75681 | 3 | 0 | 3 |
| KLHL17 | OR2T12 | 0.756439 | 3 | 0 | 3 |
| KLHL17 | SPDYE5 | 0.752901 | 3 | 0 | 3 |
| KLHL17 | CLDND2 | 0.731042 | 3 | 0 | 3 |
| KLHL17 | ALG11 | 0.729353 | 3 | 0 | 3 |
| KLHL17 | CSTF2 | 0.716359 | 3 | 0 | 3 |
| KLHL17 | RNF31 | 0.709343 | 3 | 0 | 3 |
| KLHL17 | MALT1 | 0.704856 | 3 | 0 | 3 |
| KLHL17 | ARHGEF33 | 0.698425 | 4 | 0 | 4 |
| KLHL17 | RAB37 | 0.69225 | 3 | 0 | 3 |
| KLHL17 | PAPPA | 0.69168 | 3 | 0 | 3 |
| KLHL17 | PPP4R1 | 0.683111 | 3 | 0 | 3 |
| KLHL17 | UEVLD | 0.680799 | 3 | 0 | 3 |
| KLHL17 | CCIN | 0.680051 | 5 | 0 | 4 |
| KLHL17 | TFDP3 | 0.679237 | 4 | 0 | 3 |
| KLHL17 | RIT2 | 0.679009 | 4 | 0 | 4 |
| KLHL17 | SYN3 | 0.678315 | 4 | 0 | 4 |
| KLHL17 | GLI4 | 0.677982 | 4 | 0 | 4 |
| KLHL17 | RREB1 | 0.676998 | 5 | 0 | 4 |
For details and further investigation, click here
