| Full name: eukaryotic translation initiation factor 3 subunit H | Alias Symbol: eIF3-gamma|eIF3-p40|eIF3h | ||
| Type: protein-coding gene | Cytoband: 8q23.3-q24.11 | ||
| Entrez ID: 8667 | HGNC ID: HGNC:3273 | Ensembl Gene: ENSG00000147677 | OMIM ID: 603912 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3H | 8667 | 201592_at | 0.1211 | 0.8075 | |
| GSE20347 | EIF3H | 8667 | 201592_at | -0.0692 | 0.6154 | |
| GSE23400 | EIF3H | 8667 | 201592_at | 0.0706 | 0.3567 | |
| GSE26886 | EIF3H | 8667 | 201592_at | 0.2375 | 0.2062 | |
| GSE29001 | EIF3H | 8667 | 201592_at | -0.3908 | 0.3329 | |
| GSE38129 | EIF3H | 8667 | 201592_at | 0.0448 | 0.6867 | |
| GSE45670 | EIF3H | 8667 | 201592_at | -0.0918 | 0.3602 | |
| GSE53622 | EIF3H | 8667 | 97583 | -0.2291 | 0.0001 | |
| GSE53624 | EIF3H | 8667 | 97583 | 0.0420 | 0.4864 | |
| GSE63941 | EIF3H | 8667 | 201592_at | 0.7533 | 0.0177 | |
| GSE77861 | EIF3H | 8667 | 201592_at | -0.1807 | 0.3775 | |
| GSE97050 | EIF3H | 8667 | A_23_P9061 | -0.2750 | 0.2660 | |
| SRP007169 | EIF3H | 8667 | RNAseq | -1.2900 | 0.0002 | |
| SRP008496 | EIF3H | 8667 | RNAseq | -1.1583 | 0.0000 | |
| SRP064894 | EIF3H | 8667 | RNAseq | -0.2776 | 0.1724 | |
| SRP133303 | EIF3H | 8667 | RNAseq | -0.1814 | 0.0856 | |
| SRP159526 | EIF3H | 8667 | RNAseq | -0.4328 | 0.1050 | |
| SRP193095 | EIF3H | 8667 | RNAseq | -0.5701 | 0.0000 | |
| SRP219564 | EIF3H | 8667 | RNAseq | -0.1857 | 0.6047 | |
| TCGA | EIF3H | 8667 | RNAseq | 0.0943 | 0.0343 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EIF3H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3H | 8667 | 18 | 1 | 11 | |
| GSE20123 | EIF3H | 8667 | 19 | 1 | 10 | |
| GSE43470 | EIF3H | 8667 | 22 | 0 | 21 | |
| GSE46452 | EIF3H | 8667 | 26 | 0 | 33 | |
| GSE47630 | EIF3H | 8667 | 24 | 0 | 16 | |
| GSE54993 | EIF3H | 8667 | 0 | 20 | 50 | |
| GSE54994 | EIF3H | 8667 | 37 | 1 | 15 | |
| GSE60625 | EIF3H | 8667 | 0 | 4 | 7 | |
| GSE74703 | EIF3H | 8667 | 19 | 0 | 17 | |
| GSE74704 | EIF3H | 8667 | 13 | 1 | 6 | |
| TCGA | EIF3H | 8667 | 63 | 2 | 31 |
Total number of gains: 241; Total number of losses: 30; Total Number of normals: 217.
Somatic mutations of EIF3H:
Generating mutation plots.
Highly correlated genes for EIF3H:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3H | TPR | 0.730707 | 3 | 0 | 3 |
| EIF3H | MRPS21 | 0.722833 | 3 | 0 | 3 |
| EIF3H | CLDND1 | 0.719117 | 3 | 0 | 3 |
| EIF3H | CSNK2A2 | 0.710354 | 3 | 0 | 3 |
| EIF3H | PITRM1 | 0.702502 | 3 | 0 | 3 |
| EIF3H | EXOC3L4 | 0.697814 | 3 | 0 | 3 |
| EIF3H | SERBP1 | 0.697364 | 3 | 0 | 3 |
| EIF3H | ARG2 | 0.686879 | 3 | 0 | 3 |
| EIF3H | UBE2W | 0.681387 | 3 | 0 | 3 |
| EIF3H | LARP7 | 0.676547 | 4 | 0 | 3 |
| EIF3H | TATDN1 | 0.676171 | 5 | 0 | 5 |
| EIF3H | EIF3E | 0.676157 | 12 | 0 | 11 |
| EIF3H | PPWD1 | 0.670204 | 3 | 0 | 3 |
| EIF3H | NDUFA10 | 0.666431 | 3 | 0 | 3 |
| EIF3H | FBXO32 | 0.653431 | 3 | 0 | 3 |
| EIF3H | BTBD7 | 0.652705 | 3 | 0 | 3 |
| EIF3H | BTF3L4 | 0.651904 | 4 | 0 | 3 |
| EIF3H | SLC25A29 | 0.650105 | 3 | 0 | 3 |
| EIF3H | RNF165 | 0.650031 | 3 | 0 | 3 |
| EIF3H | TSTD1 | 0.642288 | 3 | 0 | 3 |
For details and further investigation, click here
