PITRM1

 

Full name: pitrilysin metallopeptidase 1 Alias Symbol: MP1|KIAA1104|hMP1|PreP
Type: protein-coding gene Cytoband: 10p15.2
Entrez ID: 10531 HGNC ID: HGNC:17663 Ensembl Gene: ENSG00000107959 OMIM ID: 618211
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PITRM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PITRM1 10531 205273_s_at 0.1839 0.6991
GSE20347 PITRM1 10531 205273_s_at 0.0372 0.8454
GSE23400 PITRM1 10531 205273_s_at 0.1806 0.0355
GSE26886 PITRM1 10531 205273_s_at -0.5434 0.0508
GSE29001 PITRM1 10531 205273_s_at 0.0685 0.8555
GSE38129 PITRM1 10531 205273_s_at 0.0381 0.7983
GSE45670 PITRM1 10531 205273_s_at 0.2298 0.1709
GSE53622 PITRM1 10531 26245 0.0712 0.4084
GSE53624 PITRM1 10531 26245 0.1721 0.0022
GSE63941 PITRM1 10531 205273_s_at -0.5282 0.5336
GSE77861 PITRM1 10531 205273_s_at -0.1822 0.4578
GSE97050 PITRM1 10531 A_23_P52402 0.2749 0.2878
SRP007169 PITRM1 10531 RNAseq 0.1631 0.7429
SRP008496 PITRM1 10531 RNAseq 0.0371 0.9081
SRP064894 PITRM1 10531 RNAseq 0.1437 0.3752
SRP133303 PITRM1 10531 RNAseq -0.0453 0.8188
SRP159526 PITRM1 10531 RNAseq -0.1650 0.6404
SRP193095 PITRM1 10531 RNAseq -0.0180 0.8690
SRP219564 PITRM1 10531 RNAseq -0.2640 0.3800
TCGA PITRM1 10531 RNAseq -0.0300 0.5377

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PITRM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PITRM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PITRM1 10531 5 8 17
GSE20123 PITRM1 10531 5 7 18
GSE43470 PITRM1 10531 3 6 34
GSE46452 PITRM1 10531 2 14 43
GSE47630 PITRM1 10531 6 14 20
GSE54993 PITRM1 10531 11 0 59
GSE54994 PITRM1 10531 4 10 39
GSE60625 PITRM1 10531 0 0 11
GSE74703 PITRM1 10531 2 4 30
GSE74704 PITRM1 10531 1 6 13
TCGA PITRM1 10531 18 27 51

Total number of gains: 57; Total number of losses: 96; Total Number of normals: 335.  

 

Somatic mutations of PITRM1:

 

Generating mutation plots.

 

Highly correlated genes for PITRM1:

 

Showing top 20/242 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PITRM1ATG30.776827303
PITRM1GTF2H50.756119303
PITRM1DMTF10.751074303
PITRM1RLIM0.747458303
PITRM1GOT10.746896303
PITRM1ARFGEF20.746246303
PITRM1ZYG11A0.731016303
PITRM1CLK20.729638303
PITRM1ZBTB110.727716303
PITRM1EIF3A0.727518303
PITRM1LARP1B0.725214303
PITRM1ABCD40.724073303
PITRM1ZNF3000.723545303
PITRM1OMA10.72354303
PITRM1TADA10.722338303
PITRM1NDUFA100.72058303
PITRM1ILF20.719303303
PITRM1WWP10.716386403
PITRM1TFDP20.716029303
PITRM1USP160.713281303

For details and further investigation, click here