| Full name: NADH:ubiquinone oxidoreductase subunit A10 | Alias Symbol: CI-42k | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 4705 | HGNC ID: HGNC:7684 | Ensembl Gene: ENSG00000130414 | OMIM ID: 603835 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFA10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFA10 | 4705 | 217860_at | -0.0536 | 0.9619 | |
| GSE20347 | NDUFA10 | 4705 | 217860_at | -0.4999 | 0.0078 | |
| GSE23400 | NDUFA10 | 4705 | 217860_at | -0.1407 | 0.0511 | |
| GSE26886 | NDUFA10 | 4705 | 217860_at | -1.7094 | 0.0000 | |
| GSE29001 | NDUFA10 | 4705 | 217860_at | -0.3067 | 0.6324 | |
| GSE38129 | NDUFA10 | 4705 | 217860_at | -0.3615 | 0.0093 | |
| GSE45670 | NDUFA10 | 4705 | 217860_at | -0.2518 | 0.0675 | |
| GSE53622 | NDUFA10 | 4705 | 25550 | -0.1914 | 0.0045 | |
| GSE53624 | NDUFA10 | 4705 | 25550 | -0.4804 | 0.0000 | |
| GSE63941 | NDUFA10 | 4705 | 217860_at | 0.5936 | 0.1074 | |
| GSE77861 | NDUFA10 | 4705 | 217860_at | -0.1128 | 0.6487 | |
| GSE97050 | NDUFA10 | 4705 | A_24_P316489 | -0.2098 | 0.4013 | |
| SRP007169 | NDUFA10 | 4705 | RNAseq | -0.5554 | 0.0654 | |
| SRP008496 | NDUFA10 | 4705 | RNAseq | -0.7227 | 0.0006 | |
| SRP064894 | NDUFA10 | 4705 | RNAseq | -0.4456 | 0.0001 | |
| SRP133303 | NDUFA10 | 4705 | RNAseq | -0.1822 | 0.0799 | |
| SRP159526 | NDUFA10 | 4705 | RNAseq | -0.1516 | 0.3903 | |
| SRP193095 | NDUFA10 | 4705 | RNAseq | -0.5671 | 0.0000 | |
| SRP219564 | NDUFA10 | 4705 | RNAseq | -0.4642 | 0.1441 | |
| TCGA | NDUFA10 | 4705 | RNAseq | -0.1809 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NDUFA10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFA10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFA10 | 4705 | 1 | 12 | 17 | |
| GSE20123 | NDUFA10 | 4705 | 1 | 12 | 17 | |
| GSE43470 | NDUFA10 | 4705 | 1 | 9 | 33 | |
| GSE46452 | NDUFA10 | 4705 | 0 | 5 | 54 | |
| GSE47630 | NDUFA10 | 4705 | 4 | 5 | 31 | |
| GSE54993 | NDUFA10 | 4705 | 3 | 3 | 64 | |
| GSE54994 | NDUFA10 | 4705 | 8 | 9 | 36 | |
| GSE60625 | NDUFA10 | 4705 | 0 | 3 | 8 | |
| GSE74703 | NDUFA10 | 4705 | 1 | 7 | 28 | |
| GSE74704 | NDUFA10 | 4705 | 1 | 5 | 14 | |
| TCGA | NDUFA10 | 4705 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 99; Total Number of normals: 358.
Somatic mutations of NDUFA10:
Generating mutation plots.
Highly correlated genes for NDUFA10:
Showing top 20/613 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFA10 | FEM1A | 0.829574 | 3 | 0 | 3 |
| NDUFA10 | DUSP19 | 0.816451 | 3 | 0 | 3 |
| NDUFA10 | UBE2D2 | 0.796539 | 3 | 0 | 3 |
| NDUFA10 | LAPTM4A | 0.778884 | 5 | 0 | 5 |
| NDUFA10 | ABLIM2 | 0.771363 | 3 | 0 | 3 |
| NDUFA10 | DDX3X | 0.77043 | 3 | 0 | 3 |
| NDUFA10 | UBE2E2 | 0.769542 | 3 | 0 | 3 |
| NDUFA10 | VPS4B | 0.763433 | 3 | 0 | 3 |
| NDUFA10 | WDR73 | 0.763074 | 3 | 0 | 3 |
| NDUFA10 | STXBP5 | 0.763025 | 3 | 0 | 3 |
| NDUFA10 | SIAE | 0.75299 | 3 | 0 | 3 |
| NDUFA10 | CNOT7 | 0.749992 | 3 | 0 | 3 |
| NDUFA10 | NCKAP1 | 0.744844 | 3 | 0 | 3 |
| NDUFA10 | CDC123 | 0.734862 | 4 | 0 | 4 |
| NDUFA10 | UBA3 | 0.734661 | 4 | 0 | 3 |
| NDUFA10 | ABCG2 | 0.734357 | 3 | 0 | 3 |
| NDUFA10 | C4orf36 | 0.733708 | 3 | 0 | 3 |
| NDUFA10 | ACTR1A | 0.728523 | 3 | 0 | 3 |
| NDUFA10 | MAP4K5 | 0.727693 | 3 | 0 | 3 |
| NDUFA10 | GPBP1L1 | 0.724634 | 3 | 0 | 3 |
For details and further investigation, click here
