| Full name: peptidylprolyl isomerase domain and WD repeat containing 1 | Alias Symbol: KIAA0073 | ||
| Type: protein-coding gene | Cytoband: 5q12.3 | ||
| Entrez ID: 23398 | HGNC ID: HGNC:28954 | Ensembl Gene: ENSG00000113593 | OMIM ID: 618274 |
| Drug and gene relationship at DGIdb | |||
Expression of PPWD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPWD1 | 23398 | 213483_at | 0.0146 | 0.9779 | |
| GSE20347 | PPWD1 | 23398 | 213483_at | -0.0899 | 0.5404 | |
| GSE23400 | PPWD1 | 23398 | 213483_at | 0.0918 | 0.2315 | |
| GSE26886 | PPWD1 | 23398 | 213483_at | -0.6066 | 0.0693 | |
| GSE29001 | PPWD1 | 23398 | 213483_at | 0.0658 | 0.8903 | |
| GSE38129 | PPWD1 | 23398 | 213483_at | -0.0211 | 0.8809 | |
| GSE45670 | PPWD1 | 23398 | 213483_at | -0.1915 | 0.1806 | |
| GSE53622 | PPWD1 | 23398 | 78112 | -0.0145 | 0.8745 | |
| GSE53624 | PPWD1 | 23398 | 78112 | -0.0981 | 0.1513 | |
| GSE63941 | PPWD1 | 23398 | 213483_at | 0.0483 | 0.9155 | |
| GSE77861 | PPWD1 | 23398 | 213483_at | -0.2150 | 0.4894 | |
| GSE97050 | PPWD1 | 23398 | A_23_P110433 | -0.0954 | 0.7984 | |
| SRP007169 | PPWD1 | 23398 | RNAseq | 0.8400 | 0.0517 | |
| SRP008496 | PPWD1 | 23398 | RNAseq | 0.6482 | 0.1337 | |
| SRP064894 | PPWD1 | 23398 | RNAseq | -0.0819 | 0.5986 | |
| SRP133303 | PPWD1 | 23398 | RNAseq | -0.1989 | 0.1139 | |
| SRP159526 | PPWD1 | 23398 | RNAseq | -0.3689 | 0.1546 | |
| SRP193095 | PPWD1 | 23398 | RNAseq | -0.3591 | 0.0001 | |
| SRP219564 | PPWD1 | 23398 | RNAseq | -0.2686 | 0.1848 | |
| TCGA | PPWD1 | 23398 | RNAseq | -0.0601 | 0.2907 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPWD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPWD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPWD1 | 23398 | 0 | 13 | 17 | |
| GSE20123 | PPWD1 | 23398 | 0 | 13 | 17 | |
| GSE43470 | PPWD1 | 23398 | 1 | 13 | 29 | |
| GSE46452 | PPWD1 | 23398 | 0 | 28 | 31 | |
| GSE47630 | PPWD1 | 23398 | 2 | 17 | 21 | |
| GSE54993 | PPWD1 | 23398 | 8 | 1 | 61 | |
| GSE54994 | PPWD1 | 23398 | 1 | 19 | 33 | |
| GSE60625 | PPWD1 | 23398 | 0 | 0 | 11 | |
| GSE74703 | PPWD1 | 23398 | 1 | 9 | 26 | |
| GSE74704 | PPWD1 | 23398 | 0 | 6 | 14 | |
| TCGA | PPWD1 | 23398 | 3 | 50 | 43 |
Total number of gains: 16; Total number of losses: 169; Total Number of normals: 303.
Somatic mutations of PPWD1:
Generating mutation plots.
Highly correlated genes for PPWD1:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPWD1 | ANKRD13C | 0.822958 | 3 | 0 | 3 |
| PPWD1 | RPS6KB1 | 0.819469 | 3 | 0 | 3 |
| PPWD1 | SKAP2 | 0.799483 | 4 | 0 | 4 |
| PPWD1 | POLR3C | 0.791712 | 3 | 0 | 3 |
| PPWD1 | UHRF2 | 0.787759 | 3 | 0 | 3 |
| PPWD1 | MFN1 | 0.780765 | 3 | 0 | 3 |
| PPWD1 | ATG2B | 0.769276 | 3 | 0 | 3 |
| PPWD1 | MFSD6 | 0.760474 | 3 | 0 | 3 |
| PPWD1 | PHF20 | 0.757749 | 3 | 0 | 3 |
| PPWD1 | UBE2E1 | 0.754125 | 3 | 0 | 3 |
| PPWD1 | SNX12 | 0.750093 | 3 | 0 | 3 |
| PPWD1 | DRAM2 | 0.743406 | 3 | 0 | 3 |
| PPWD1 | WWP1 | 0.74156 | 3 | 0 | 3 |
| PPWD1 | SLC35A3 | 0.741375 | 4 | 0 | 4 |
| PPWD1 | FAM8A1 | 0.741286 | 3 | 0 | 3 |
| PPWD1 | SRPRB | 0.72873 | 3 | 0 | 3 |
| PPWD1 | GLCCI1 | 0.728688 | 3 | 0 | 3 |
| PPWD1 | AK3 | 0.722965 | 3 | 0 | 3 |
| PPWD1 | RPA2 | 0.72143 | 3 | 0 | 3 |
| PPWD1 | MTIF2 | 0.717031 | 3 | 0 | 3 |
For details and further investigation, click here
