| Full name: La ribonucleoprotein domain family member 7 | Alias Symbol: HDCMA18P|PIP7S|DKFZP564K112 | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 51574 | HGNC ID: HGNC:24912 | Ensembl Gene: ENSG00000174720 | OMIM ID: 612026 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LARP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARP7 | 51574 | 212785_s_at | -0.2330 | 0.5946 | |
| GSE20347 | LARP7 | 51574 | 212785_s_at | -0.3378 | 0.0087 | |
| GSE23400 | LARP7 | 51574 | 212785_s_at | 0.0282 | 0.7245 | |
| GSE26886 | LARP7 | 51574 | 212785_s_at | 0.1823 | 0.4350 | |
| GSE29001 | LARP7 | 51574 | 212785_s_at | 0.1085 | 0.8208 | |
| GSE38129 | LARP7 | 51574 | 212785_s_at | -0.2603 | 0.1309 | |
| GSE45670 | LARP7 | 51574 | 212785_s_at | -0.2425 | 0.0203 | |
| GSE53622 | LARP7 | 51574 | 64558 | -0.1792 | 0.0017 | |
| GSE53624 | LARP7 | 51574 | 64558 | 0.0179 | 0.8111 | |
| GSE63941 | LARP7 | 51574 | 212785_s_at | -0.5348 | 0.1269 | |
| GSE77861 | LARP7 | 51574 | 212785_s_at | -0.1676 | 0.6062 | |
| GSE97050 | LARP7 | 51574 | A_24_P332230 | -0.5546 | 0.1224 | |
| SRP007169 | LARP7 | 51574 | RNAseq | 1.6687 | 0.0016 | |
| SRP008496 | LARP7 | 51574 | RNAseq | 2.0456 | 0.0000 | |
| SRP064894 | LARP7 | 51574 | RNAseq | 0.0313 | 0.8599 | |
| SRP133303 | LARP7 | 51574 | RNAseq | 0.2386 | 0.1454 | |
| SRP159526 | LARP7 | 51574 | RNAseq | -0.4063 | 0.0042 | |
| SRP193095 | LARP7 | 51574 | RNAseq | -0.2610 | 0.0366 | |
| SRP219564 | LARP7 | 51574 | RNAseq | -0.1829 | 0.5836 | |
| TCGA | LARP7 | 51574 | RNAseq | -0.0359 | 0.4913 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LARP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LARP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARP7 | 51574 | 1 | 13 | 16 | |
| GSE20123 | LARP7 | 51574 | 1 | 13 | 16 | |
| GSE43470 | LARP7 | 51574 | 0 | 14 | 29 | |
| GSE46452 | LARP7 | 51574 | 1 | 36 | 22 | |
| GSE47630 | LARP7 | 51574 | 0 | 20 | 20 | |
| GSE54993 | LARP7 | 51574 | 9 | 0 | 61 | |
| GSE54994 | LARP7 | 51574 | 1 | 11 | 41 | |
| GSE60625 | LARP7 | 51574 | 0 | 3 | 8 | |
| GSE74703 | LARP7 | 51574 | 0 | 12 | 24 | |
| GSE74704 | LARP7 | 51574 | 0 | 7 | 13 | |
| TCGA | LARP7 | 51574 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.
Somatic mutations of LARP7:
Generating mutation plots.
Highly correlated genes for LARP7:
Showing top 20/653 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARP7 | CBLL1 | 0.819487 | 3 | 0 | 3 |
| LARP7 | NEK3 | 0.788893 | 3 | 0 | 3 |
| LARP7 | TYW3 | 0.763001 | 3 | 0 | 3 |
| LARP7 | FAM200A | 0.739918 | 3 | 0 | 3 |
| LARP7 | PMS1 | 0.737108 | 3 | 0 | 3 |
| LARP7 | CEP63 | 0.720901 | 4 | 0 | 3 |
| LARP7 | ANAPC16 | 0.718495 | 4 | 0 | 4 |
| LARP7 | STAG2 | 0.717554 | 4 | 0 | 3 |
| LARP7 | NDUFS1 | 0.715511 | 3 | 0 | 3 |
| LARP7 | TAF7 | 0.710711 | 4 | 0 | 3 |
| LARP7 | GOLGA5 | 0.705708 | 3 | 0 | 3 |
| LARP7 | UXS1 | 0.704493 | 3 | 0 | 3 |
| LARP7 | EI24 | 0.703986 | 3 | 0 | 3 |
| LARP7 | PPP2R5E | 0.703251 | 3 | 0 | 3 |
| LARP7 | MPHOSPH9 | 0.69788 | 3 | 0 | 3 |
| LARP7 | RNF139 | 0.697727 | 3 | 0 | 3 |
| LARP7 | SFR1 | 0.6971 | 3 | 0 | 3 |
| LARP7 | PAN3 | 0.69446 | 4 | 0 | 4 |
| LARP7 | ZNF615 | 0.693974 | 4 | 0 | 3 |
| LARP7 | CRK | 0.690965 | 3 | 0 | 3 |
For details and further investigation, click here
