| Full name: ectonucleoside triphosphate diphosphohydrolase 2 | Alias Symbol: NTPDase-2 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 954 | HGNC ID: HGNC:3364 | Ensembl Gene: ENSG00000054179 | OMIM ID: 602012 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD2 | 954 | 230430_at | -0.1276 | 0.7134 | |
| GSE20347 | ENTPD2 | 954 | 207372_s_at | -0.0873 | 0.3193 | |
| GSE23400 | ENTPD2 | 954 | 207372_s_at | -0.1424 | 0.0000 | |
| GSE26886 | ENTPD2 | 954 | 230430_at | 0.3259 | 0.0723 | |
| GSE29001 | ENTPD2 | 954 | 207372_s_at | -0.1370 | 0.3690 | |
| GSE38129 | ENTPD2 | 954 | 207372_s_at | -0.0836 | 0.5201 | |
| GSE45670 | ENTPD2 | 954 | 230430_at | 0.0810 | 0.6545 | |
| GSE53622 | ENTPD2 | 954 | 159031 | 0.4063 | 0.0000 | |
| GSE53624 | ENTPD2 | 954 | 159031 | -0.1025 | 0.3202 | |
| GSE63941 | ENTPD2 | 954 | 207372_s_at | -0.1262 | 0.4835 | |
| GSE77861 | ENTPD2 | 954 | 207372_s_at | 0.0238 | 0.8744 | |
| GSE97050 | ENTPD2 | 954 | A_33_P3278649 | -0.0058 | 0.9804 | |
| SRP064894 | ENTPD2 | 954 | RNAseq | 0.1177 | 0.7875 | |
| SRP133303 | ENTPD2 | 954 | RNAseq | -0.6662 | 0.0338 | |
| SRP159526 | ENTPD2 | 954 | RNAseq | 0.9184 | 0.2329 | |
| TCGA | ENTPD2 | 954 | RNAseq | -0.0443 | 0.8344 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ENTPD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD2 | 954 | 5 | 7 | 18 | |
| GSE20123 | ENTPD2 | 954 | 5 | 7 | 18 | |
| GSE43470 | ENTPD2 | 954 | 3 | 7 | 33 | |
| GSE46452 | ENTPD2 | 954 | 6 | 13 | 40 | |
| GSE47630 | ENTPD2 | 954 | 6 | 15 | 19 | |
| GSE54993 | ENTPD2 | 954 | 3 | 3 | 64 | |
| GSE54994 | ENTPD2 | 954 | 12 | 8 | 33 | |
| GSE60625 | ENTPD2 | 954 | 0 | 0 | 11 | |
| GSE74703 | ENTPD2 | 954 | 3 | 5 | 28 | |
| GSE74704 | ENTPD2 | 954 | 3 | 5 | 12 | |
| TCGA | ENTPD2 | 954 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of ENTPD2:
Generating mutation plots.
Highly correlated genes for ENTPD2:
Showing top 20/752 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD2 | SFTPA2 | 0.822818 | 3 | 0 | 3 |
| ENTPD2 | KRTAP19-2 | 0.790201 | 3 | 0 | 3 |
| ENTPD2 | OR2T12 | 0.782877 | 3 | 0 | 3 |
| ENTPD2 | ANKRD65 | 0.778773 | 3 | 0 | 3 |
| ENTPD2 | STAT2 | 0.777039 | 3 | 0 | 3 |
| ENTPD2 | KIR3DL2 | 0.770892 | 3 | 0 | 3 |
| ENTPD2 | LIPF | 0.7684 | 3 | 0 | 3 |
| ENTPD2 | THRB | 0.759196 | 3 | 0 | 3 |
| ENTPD2 | SLC26A5 | 0.758128 | 3 | 0 | 3 |
| ENTPD2 | ZNF878 | 0.757918 | 3 | 0 | 3 |
| ENTPD2 | OR2T33 | 0.75512 | 4 | 0 | 4 |
| ENTPD2 | CYP26C1 | 0.750733 | 3 | 0 | 3 |
| ENTPD2 | PI16 | 0.747739 | 3 | 0 | 3 |
| ENTPD2 | PHLDB1 | 0.74749 | 6 | 0 | 6 |
| ENTPD2 | MEIS3 | 0.745134 | 3 | 0 | 3 |
| ENTPD2 | PLIN4 | 0.745073 | 3 | 0 | 3 |
| ENTPD2 | CDH24 | 0.743843 | 4 | 0 | 4 |
| ENTPD2 | KRTAP10-4 | 0.737905 | 3 | 0 | 3 |
| ENTPD2 | IQCC | 0.734347 | 6 | 0 | 6 |
| ENTPD2 | ELFN1 | 0.733521 | 5 | 0 | 4 |
For details and further investigation, click here
