| Full name: peptidase inhibitor 16 | Alias Symbol: MGC45378|dJ90K10.5|MSMBBP|CD364 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 221476 | HGNC ID: HGNC:21245 | Ensembl Gene: ENSG00000164530 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PI16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PI16 | 221476 | 228312_at | -0.2911 | 0.6256 | |
| GSE26886 | PI16 | 221476 | 228312_at | 0.2706 | 0.0367 | |
| GSE45670 | PI16 | 221476 | 228312_at | -0.3777 | 0.0008 | |
| GSE53622 | PI16 | 221476 | 30764 | -3.4920 | 0.0000 | |
| GSE53624 | PI16 | 221476 | 30764 | -3.4186 | 0.0000 | |
| GSE63941 | PI16 | 221476 | 228312_at | -0.1022 | 0.5852 | |
| GSE77861 | PI16 | 221476 | 228312_at | 0.0977 | 0.6229 | |
| GSE97050 | PI16 | 221476 | A_33_P3215640 | -1.2882 | 0.2186 | |
| SRP064894 | PI16 | 221476 | RNAseq | -1.1491 | 0.1003 | |
| SRP133303 | PI16 | 221476 | RNAseq | -3.1763 | 0.0000 | |
| SRP159526 | PI16 | 221476 | RNAseq | -1.5188 | 0.1500 | |
| TCGA | PI16 | 221476 | RNAseq | -2.5564 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by PI16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PI16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PI16 | 221476 | 6 | 0 | 24 | |
| GSE20123 | PI16 | 221476 | 6 | 0 | 24 | |
| GSE43470 | PI16 | 221476 | 5 | 1 | 37 | |
| GSE46452 | PI16 | 221476 | 2 | 9 | 48 | |
| GSE47630 | PI16 | 221476 | 8 | 4 | 28 | |
| GSE54993 | PI16 | 221476 | 3 | 1 | 66 | |
| GSE54994 | PI16 | 221476 | 10 | 5 | 38 | |
| GSE60625 | PI16 | 221476 | 1 | 0 | 10 | |
| GSE74703 | PI16 | 221476 | 5 | 0 | 31 | |
| GSE74704 | PI16 | 221476 | 3 | 0 | 17 | |
| TCGA | PI16 | 221476 | 15 | 14 | 67 |
Total number of gains: 64; Total number of losses: 34; Total Number of normals: 390.
Somatic mutations of PI16:
Generating mutation plots.
Highly correlated genes for PI16:
Showing top 20/828 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PI16 | CYP21A2 | 0.898473 | 3 | 0 | 3 |
| PI16 | UBXN10 | 0.88901 | 3 | 0 | 3 |
| PI16 | KCNB1 | 0.838439 | 4 | 0 | 4 |
| PI16 | HSPB6 | 0.835699 | 4 | 0 | 4 |
| PI16 | ZNF683 | 0.814555 | 3 | 0 | 3 |
| PI16 | CCL14 | 0.813074 | 3 | 0 | 3 |
| PI16 | NKX6-1 | 0.804475 | 4 | 0 | 4 |
| PI16 | ASB5 | 0.793993 | 4 | 0 | 4 |
| PI16 | CLEC3B | 0.792119 | 4 | 0 | 3 |
| PI16 | RERGL | 0.786565 | 4 | 0 | 4 |
| PI16 | CFL2 | 0.783964 | 4 | 0 | 4 |
| PI16 | CKMT2 | 0.781308 | 5 | 0 | 5 |
| PI16 | ABCA6 | 0.779676 | 6 | 0 | 6 |
| PI16 | PARD3B | 0.779593 | 4 | 0 | 4 |
| PI16 | HPSE2 | 0.775285 | 5 | 0 | 4 |
| PI16 | C1QTNF7 | 0.774307 | 5 | 0 | 5 |
| PI16 | NCAM1 | 0.773722 | 5 | 0 | 4 |
| PI16 | PROS1 | 0.77217 | 3 | 0 | 3 |
| PI16 | FRRS1L | 0.770236 | 3 | 0 | 3 |
| PI16 | ZBTB10 | 0.767233 | 3 | 0 | 3 |
For details and further investigation, click here
