KLRG2

 

Full name: killer cell lectin like receptor G2 Alias Symbol: FLJ44186|CLEC15B
Type: protein-coding gene Cytoband: 7q34
Entrez ID: 346689 HGNC ID: HGNC:24778 Ensembl Gene: ENSG00000188883 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of KLRG2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KLRG2 346689 244264_at 0.3660 0.7747
GSE26886 KLRG2 346689 244264_at -0.0762 0.8401
GSE45670 KLRG2 346689 244264_at 0.5880 0.2245
GSE53622 KLRG2 346689 57634 0.2382 0.0002
GSE53624 KLRG2 346689 57634 0.2877 0.0000
GSE63941 KLRG2 346689 244264_at 2.2545 0.0057
GSE77861 KLRG2 346689 231195_at 0.4817 0.0460
GSE97050 KLRG2 346689 A_33_P3306207 -0.0087 0.9707
SRP007169 KLRG2 346689 RNAseq 0.2926 0.5816
SRP008496 KLRG2 346689 RNAseq 1.2545 0.0081
SRP064894 KLRG2 346689 RNAseq -0.3874 0.3335
SRP133303 KLRG2 346689 RNAseq -0.3762 0.4090
SRP159526 KLRG2 346689 RNAseq 1.1007 0.0499
SRP219564 KLRG2 346689 RNAseq -0.0129 0.9897
TCGA KLRG2 346689 RNAseq 1.6822 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  


 

Survival by KLRG2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KLRG2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KLRG2 346689 5 2 23
GSE20123 KLRG2 346689 5 2 23
GSE43470 KLRG2 346689 2 3 38
GSE46452 KLRG2 346689 7 2 50
GSE47630 KLRG2 346689 7 4 29
GSE54993 KLRG2 346689 3 5 62
GSE54994 KLRG2 346689 5 8 40
GSE60625 KLRG2 346689 0 0 11
GSE74703 KLRG2 346689 2 3 31
GSE74704 KLRG2 346689 1 2 17
TCGA KLRG2 346689 28 23 45

Total number of gains: 65; Total number of losses: 54; Total Number of normals: 369.  


 

Somatic mutations of KLRG2:

 

Generating mutation plots.

 

Highly correlated genes for KLRG2:

 

Showing top 20/178 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KLRG2EVX10.823678303
KLRG2MRGPRG0.818654303
KLRG2ANKRD330.816503303
KLRG2NPPB0.791884303
KLRG2ZNF5270.78543303
KLRG2MYH140.76664303
KLRG2FFAR10.763075303
KLRG2STAC30.762448303
KLRG2SYCE1L0.757229303
KLRG2C9orf1530.746172303
KLRG2C1QL20.745509303
KLRG2YY20.744706303
KLRG2MAFA0.744585303
KLRG2MEGF110.742691303
KLRG2C2CD4D0.742025303
KLRG2LHB0.740606303
KLRG2FBRSL10.740146606
KLRG2GTF2IRD20.734529303
KLRG2C19orf440.732021303
KLRG2HCN30.729584303

For details and further investigation, click here