| Full name: multiple EGF like domains 11 | Alias Symbol: KIAA1781|DKFZp434L121 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 84465 | HGNC ID: HGNC:29635 | Ensembl Gene: ENSG00000157890 | OMIM ID: 612454 |
| Drug and gene relationship at DGIdb | |||
Expression of MEGF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEGF11 | 84465 | 1569879_a_at | -0.0835 | 0.7727 | |
| GSE26886 | MEGF11 | 84465 | 1569879_a_at | -0.2153 | 0.0863 | |
| GSE45670 | MEGF11 | 84465 | 1569879_a_at | -0.0229 | 0.8529 | |
| GSE53622 | MEGF11 | 84465 | 40872 | 0.3393 | 0.0000 | |
| GSE53624 | MEGF11 | 84465 | 40872 | 0.4708 | 0.0000 | |
| GSE63941 | MEGF11 | 84465 | 1569879_a_at | 0.3640 | 0.0350 | |
| GSE77861 | MEGF11 | 84465 | 1569879_a_at | -0.1664 | 0.2558 | |
| GSE97050 | MEGF11 | 84465 | A_33_P3312790 | 0.2922 | 0.3113 | |
| SRP133303 | MEGF11 | 84465 | RNAseq | -0.9950 | 0.0004 | |
| SRP193095 | MEGF11 | 84465 | RNAseq | -0.9210 | 0.0000 | |
| TCGA | MEGF11 | 84465 | RNAseq | -1.1256 | 0.0069 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MEGF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEGF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEGF11 | 84465 | 6 | 4 | 20 | |
| GSE20123 | MEGF11 | 84465 | 6 | 4 | 20 | |
| GSE43470 | MEGF11 | 84465 | 4 | 6 | 33 | |
| GSE46452 | MEGF11 | 84465 | 3 | 7 | 49 | |
| GSE47630 | MEGF11 | 84465 | 8 | 10 | 22 | |
| GSE54993 | MEGF11 | 84465 | 5 | 6 | 59 | |
| GSE54994 | MEGF11 | 84465 | 6 | 7 | 40 | |
| GSE60625 | MEGF11 | 84465 | 4 | 0 | 7 | |
| GSE74703 | MEGF11 | 84465 | 4 | 3 | 29 | |
| GSE74704 | MEGF11 | 84465 | 3 | 3 | 14 | |
| TCGA | MEGF11 | 84465 | 9 | 16 | 71 |
Total number of gains: 58; Total number of losses: 66; Total Number of normals: 364.
Somatic mutations of MEGF11:
Generating mutation plots.
Highly correlated genes for MEGF11:
Showing top 20/565 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEGF11 | SLC6A3 | 0.878708 | 3 | 0 | 3 |
| MEGF11 | GNB3 | 0.828541 | 3 | 0 | 3 |
| MEGF11 | C1QL2 | 0.824956 | 3 | 0 | 3 |
| MEGF11 | MRGPRG | 0.810793 | 3 | 0 | 3 |
| MEGF11 | DCDC1 | 0.809072 | 3 | 0 | 3 |
| MEGF11 | PABPN1L | 0.806831 | 3 | 0 | 3 |
| MEGF11 | MS4A18 | 0.803587 | 3 | 0 | 3 |
| MEGF11 | PSMB11 | 0.797883 | 3 | 0 | 3 |
| MEGF11 | EVX1 | 0.794091 | 3 | 0 | 3 |
| MEGF11 | LHB | 0.793806 | 3 | 0 | 3 |
| MEGF11 | GRIK4 | 0.791838 | 3 | 0 | 3 |
| MEGF11 | C2CD4D | 0.791829 | 3 | 0 | 3 |
| MEGF11 | STRC | 0.778247 | 3 | 0 | 3 |
| MEGF11 | OR2A5 | 0.776913 | 3 | 0 | 3 |
| MEGF11 | PLA2G2C | 0.773831 | 3 | 0 | 3 |
| MEGF11 | YY2 | 0.75785 | 3 | 0 | 3 |
| MEGF11 | OR5A1 | 0.754245 | 3 | 0 | 3 |
| MEGF11 | OR2T1 | 0.754211 | 3 | 0 | 3 |
| MEGF11 | GH1 | 0.752292 | 3 | 0 | 3 |
| MEGF11 | C19orf71 | 0.751657 | 3 | 0 | 3 |
For details and further investigation, click here
