| Full name: ladybird homeobox 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 85474 | HGNC ID: HGNC:15525 | Ensembl Gene: ENSG00000179528 | OMIM ID: 607164 |
| Drug and gene relationship at DGIdb | |||
Expression of LBX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LBX2 | 85474 | 15173 | 0.2656 | 0.0253 | |
| GSE53624 | LBX2 | 85474 | 15173 | -0.0315 | 0.7791 | |
| GSE97050 | LBX2 | 85474 | A_33_P3392517 | -0.1035 | 0.6741 | |
| SRP133303 | LBX2 | 85474 | RNAseq | 0.9309 | 0.0077 | |
| SRP159526 | LBX2 | 85474 | RNAseq | 3.6246 | 0.0000 | |
| SRP219564 | LBX2 | 85474 | RNAseq | 1.5682 | 0.0071 | |
| TCGA | LBX2 | 85474 | RNAseq | 1.3794 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LBX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LBX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LBX2 | 85474 | 9 | 2 | 19 | |
| GSE20123 | LBX2 | 85474 | 10 | 2 | 18 | |
| GSE43470 | LBX2 | 85474 | 4 | 0 | 39 | |
| GSE46452 | LBX2 | 85474 | 2 | 3 | 54 | |
| GSE47630 | LBX2 | 85474 | 7 | 0 | 33 | |
| GSE54993 | LBX2 | 85474 | 0 | 6 | 64 | |
| GSE54994 | LBX2 | 85474 | 10 | 0 | 43 | |
| GSE60625 | LBX2 | 85474 | 0 | 3 | 8 | |
| GSE74703 | LBX2 | 85474 | 4 | 0 | 32 | |
| GSE74704 | LBX2 | 85474 | 8 | 0 | 12 | |
| TCGA | LBX2 | 85474 | 37 | 2 | 57 |
Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.
Somatic mutations of LBX2:
Generating mutation plots.
Highly correlated genes for LBX2:
Showing top 20/292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LBX2 | GJD4 | 0.877065 | 3 | 0 | 3 |
| LBX2 | ZNF527 | 0.86681 | 3 | 0 | 3 |
| LBX2 | SPRED3 | 0.861932 | 3 | 0 | 3 |
| LBX2 | RNF180 | 0.855007 | 3 | 0 | 3 |
| LBX2 | TNFAIP8L1 | 0.853856 | 3 | 0 | 3 |
| LBX2 | RBM43 | 0.853437 | 3 | 0 | 3 |
| LBX2 | YY2 | 0.836484 | 3 | 0 | 3 |
| LBX2 | FBRSL1 | 0.828183 | 3 | 0 | 3 |
| LBX2 | SLC22A31 | 0.825132 | 3 | 0 | 3 |
| LBX2 | CNOT3 | 0.815768 | 3 | 0 | 3 |
| LBX2 | CLDN9 | 0.814947 | 3 | 0 | 3 |
| LBX2 | C9orf153 | 0.812984 | 3 | 0 | 3 |
| LBX2 | ZNF763 | 0.812374 | 3 | 0 | 3 |
| LBX2 | KCNH3 | 0.808163 | 3 | 0 | 3 |
| LBX2 | RAX2 | 0.804437 | 3 | 0 | 3 |
| LBX2 | NKX6-3 | 0.800988 | 3 | 0 | 3 |
| LBX2 | TFE3 | 0.800128 | 3 | 0 | 3 |
| LBX2 | ST8SIA1 | 0.799767 | 3 | 0 | 3 |
| LBX2 | PRSS38 | 0.797956 | 3 | 0 | 3 |
| LBX2 | TXNDC2 | 0.796325 | 3 | 0 | 3 |
For details and further investigation, click here
