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Multi-Omics Database of ESCC

 

ARHGAP30

 

Full name: Rho GTPase activating protein 30 Alias Symbol: FLJ00267
Type: protein-coding gene Cytoband: 1q23.3
Entrez ID: 257106 HGNC ID: HGNC:27414 Ensembl Gene: ENSG00000186517 OMIM ID: 614264
Drug and gene relationship at DGIdb

 

Expression of ARHGAP30:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ARHGAP30 257106 226219_at -0.2375 0.8602
GSE26886 ARHGAP30 257106 241346_at 0.1749 0.2986
GSE45670 ARHGAP30 257106 226219_at -0.7917 0.0002
GSE53622 ARHGAP30 257106 113618 0.2803 0.0000
GSE53624 ARHGAP30 257106 86631 -0.8004 0.0000
GSE63941 ARHGAP30 257106 241346_at 0.3209 0.0261
GSE77861 ARHGAP30 257106 241346_at -0.1584 0.4739
GSE97050 ARHGAP30 257106 A_33_P3213910 0.2192 0.3823
SRP007169 ARHGAP30 257106 RNAseq 0.1930 0.7431
SRP008496 ARHGAP30 257106 RNAseq 0.1952 0.6170
SRP064894 ARHGAP30 257106 RNAseq -1.0950 0.0000
SRP133303 ARHGAP30 257106 RNAseq -0.7032 0.0019
SRP159526 ARHGAP30 257106 RNAseq -1.1929 0.0332
SRP193095 ARHGAP30 257106 RNAseq -0.1575 0.3425
SRP219564 ARHGAP30 257106 RNAseq -0.9533 0.0886
TCGA ARHGAP30 257106 RNAseq 0.0977 0.3004

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by ARHGAP30 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ARHGAP30:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ARHGAP30 257106 10 0 20
GSE20123 ARHGAP30 257106 10 0 20
GSE43470 ARHGAP30 257106 7 2 34
GSE46452 ARHGAP30 257106 2 1 56
GSE47630 ARHGAP30 257106 14 0 26
GSE54993 ARHGAP30 257106 0 6 64
GSE54994 ARHGAP30 257106 16 0 37
GSE60625 ARHGAP30 257106 0 0 11
GSE74703 ARHGAP30 257106 7 2 27
GSE74704 ARHGAP30 257106 4 0 16
TCGA ARHGAP30 257106 45 3 48

Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.  

 

Somatic mutations of ARHGAP30:

 

Generating mutation plots.

 

Highly correlated genes for ARHGAP30:

 

Showing top 20/214 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ARHGAP30ADAMTS70.876374303
ARHGAP30ARMC50.865702303
ARHGAP30CEMP10.823002303
ARHGAP30ZMYND100.813305303
ARHGAP30ACAD100.798593303
ARHGAP30EVX10.797675404
ARHGAP30AIRE0.79324303
ARHGAP30MGAT5B0.792103303
ARHGAP30DPYSL40.78938303
ARHGAP30ABCB90.788903303
ARHGAP30DNAJB80.787968303
ARHGAP30SLC16A110.784953303
ARHGAP30RRP10.778522303
ARHGAP30CLCN10.77479303
ARHGAP30AGER0.77074404
ARHGAP30PLD40.760455404
ARHGAP30JSRP10.757571504
ARHGAP30NPEPL10.757275403
ARHGAP30CDH40.755445303
ARHGAP30SEMA3B0.753124404

For details and further investigation, click here