| Full name: cell division cycle 34 | Alias Symbol: E2-CDC34|UBE2R1|UBC3 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 997 | HGNC ID: HGNC:1734 | Ensembl Gene: ENSG00000099804 | OMIM ID: 116948 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC34 | 997 | 212540_at | 0.2444 | 0.6479 | |
| GSE20347 | CDC34 | 997 | 212540_at | -0.1173 | 0.4679 | |
| GSE23400 | CDC34 | 997 | 212540_at | -0.1789 | 0.0126 | |
| GSE26886 | CDC34 | 997 | 212540_at | 0.2672 | 0.2095 | |
| GSE29001 | CDC34 | 997 | 212540_at | -0.1915 | 0.4025 | |
| GSE38129 | CDC34 | 997 | 212540_at | -0.1234 | 0.3251 | |
| GSE45670 | CDC34 | 997 | 212540_at | 0.1279 | 0.3809 | |
| GSE63941 | CDC34 | 997 | 212540_at | 0.3083 | 0.4535 | |
| GSE77861 | CDC34 | 997 | 212540_at | 0.1951 | 0.3105 | |
| GSE97050 | CDC34 | 997 | A_23_P164999 | 0.0095 | 0.9686 | |
| SRP007169 | CDC34 | 997 | RNAseq | -1.7555 | 0.0000 | |
| SRP008496 | CDC34 | 997 | RNAseq | -1.6073 | 0.0000 | |
| SRP064894 | CDC34 | 997 | RNAseq | 0.0620 | 0.8540 | |
| SRP133303 | CDC34 | 997 | RNAseq | -0.2494 | 0.1770 | |
| SRP159526 | CDC34 | 997 | RNAseq | -0.0879 | 0.7154 | |
| SRP193095 | CDC34 | 997 | RNAseq | -0.3019 | 0.0270 | |
| SRP219564 | CDC34 | 997 | RNAseq | -0.2713 | 0.3635 | |
| TCGA | CDC34 | 997 | RNAseq | 0.0354 | 0.5404 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CDC34 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CDC34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC34 | 997 | 4 | 6 | 20 | |
| GSE20123 | CDC34 | 997 | 4 | 5 | 21 | |
| GSE43470 | CDC34 | 997 | 1 | 10 | 32 | |
| GSE46452 | CDC34 | 997 | 47 | 1 | 11 | |
| GSE47630 | CDC34 | 997 | 5 | 7 | 28 | |
| GSE54993 | CDC34 | 997 | 13 | 4 | 53 | |
| GSE54994 | CDC34 | 997 | 8 | 15 | 30 | |
| GSE60625 | CDC34 | 997 | 9 | 0 | 2 | |
| GSE74703 | CDC34 | 997 | 1 | 7 | 28 | |
| GSE74704 | CDC34 | 997 | 3 | 3 | 14 | |
| TCGA | CDC34 | 997 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of CDC34:
Generating mutation plots.
Highly correlated genes for CDC34:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC34 | EVX1 | 0.783267 | 3 | 0 | 3 |
| CDC34 | HRK | 0.773884 | 3 | 0 | 3 |
| CDC34 | ING5 | 0.770207 | 3 | 0 | 3 |
| CDC34 | C19orf25 | 0.754942 | 4 | 0 | 4 |
| CDC34 | MAG | 0.754234 | 3 | 0 | 3 |
| CDC34 | OR7A17 | 0.749214 | 3 | 0 | 3 |
| CDC34 | ZNF687 | 0.743926 | 3 | 0 | 3 |
| CDC34 | ORM1 | 0.742968 | 3 | 0 | 3 |
| CDC34 | GPC2 | 0.723415 | 3 | 0 | 3 |
| CDC34 | TRIM41 | 0.722801 | 3 | 0 | 3 |
| CDC34 | IER5L | 0.722372 | 3 | 0 | 3 |
| CDC34 | IGHMBP2 | 0.717704 | 3 | 0 | 3 |
| CDC34 | TMEM104 | 0.712879 | 3 | 0 | 3 |
| CDC34 | TNNI2 | 0.712104 | 3 | 0 | 3 |
| CDC34 | SOHLH1 | 0.708865 | 3 | 0 | 3 |
| CDC34 | MIIP | 0.706961 | 4 | 0 | 3 |
| CDC34 | ITGA2B | 0.706786 | 4 | 0 | 3 |
| CDC34 | CDK12 | 0.706604 | 3 | 0 | 3 |
| CDC34 | C19orf81 | 0.697814 | 4 | 0 | 3 |
| CDC34 | RIMS4 | 0.694189 | 3 | 0 | 3 |
For details and further investigation, click here
