| Full name: exonuclease 5 | Alias Symbol: FLJ21144 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 64789 | HGNC ID: HGNC:26115 | Ensembl Gene: ENSG00000164002 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EXO5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXO5 | 64789 | 222902_s_at | 0.5907 | 0.2400 | |
| GSE20347 | EXO5 | 64789 | 219567_s_at | 0.0964 | 0.2232 | |
| GSE23400 | EXO5 | 64789 | 219567_s_at | 0.0758 | 0.0627 | |
| GSE26886 | EXO5 | 64789 | 222902_s_at | -0.0826 | 0.7570 | |
| GSE29001 | EXO5 | 64789 | 219567_s_at | 0.1246 | 0.6378 | |
| GSE38129 | EXO5 | 64789 | 219567_s_at | 0.1103 | 0.1028 | |
| GSE45670 | EXO5 | 64789 | 222902_s_at | 0.1676 | 0.3029 | |
| GSE63941 | EXO5 | 64789 | 222902_s_at | 0.1556 | 0.7930 | |
| GSE77861 | EXO5 | 64789 | 222902_s_at | -0.1224 | 0.4775 | |
| SRP007169 | EXO5 | 64789 | RNAseq | 0.8710 | 0.1780 | |
| SRP064894 | EXO5 | 64789 | RNAseq | 0.4873 | 0.0158 | |
| SRP133303 | EXO5 | 64789 | RNAseq | 0.6251 | 0.0126 | |
| SRP159526 | EXO5 | 64789 | RNAseq | 0.9459 | 0.0521 | |
| SRP193095 | EXO5 | 64789 | RNAseq | 0.3447 | 0.0068 | |
| SRP219564 | EXO5 | 64789 | RNAseq | 0.5284 | 0.1164 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of EXO5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXO5 | 64789 | 3 | 4 | 23 | |
| GSE20123 | EXO5 | 64789 | 2 | 3 | 25 | |
| GSE43470 | EXO5 | 64789 | 7 | 2 | 34 | |
| GSE46452 | EXO5 | 64789 | 4 | 1 | 54 | |
| GSE47630 | EXO5 | 64789 | 9 | 2 | 29 | |
| GSE54993 | EXO5 | 64789 | 0 | 1 | 69 | |
| GSE54994 | EXO5 | 64789 | 13 | 2 | 38 | |
| GSE60625 | EXO5 | 64789 | 0 | 0 | 11 | |
| GSE74703 | EXO5 | 64789 | 6 | 1 | 29 | |
| GSE74704 | EXO5 | 64789 | 1 | 0 | 19 | |
| TCGA | EXO5 | 64789 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of EXO5:
Generating mutation plots.
Highly correlated genes for EXO5:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXO5 | ZNF140 | 0.671457 | 3 | 0 | 3 |
| EXO5 | RBBP7 | 0.669646 | 3 | 0 | 3 |
| EXO5 | BRWD1 | 0.666106 | 3 | 0 | 3 |
| EXO5 | ACTR6 | 0.665262 | 3 | 0 | 3 |
| EXO5 | NIPAL3 | 0.653377 | 3 | 0 | 3 |
| EXO5 | ARFGEF1 | 0.651009 | 3 | 0 | 3 |
| EXO5 | ZYG11A | 0.649654 | 3 | 0 | 3 |
| EXO5 | SNRPD3 | 0.641591 | 3 | 0 | 3 |
| EXO5 | B3GALNT1 | 0.636666 | 4 | 0 | 3 |
| EXO5 | ZSCAN16 | 0.629352 | 4 | 0 | 3 |
| EXO5 | RMND1 | 0.6291 | 3 | 0 | 3 |
| EXO5 | SNUPN | 0.625868 | 3 | 0 | 3 |
| EXO5 | ZNF320 | 0.625047 | 4 | 0 | 3 |
| EXO5 | RYK | 0.62284 | 3 | 0 | 3 |
| EXO5 | SLC35A5 | 0.621643 | 3 | 0 | 3 |
| EXO5 | ZNF684 | 0.618953 | 4 | 0 | 3 |
| EXO5 | ZNF304 | 0.613449 | 3 | 0 | 3 |
| EXO5 | PTPRK | 0.613083 | 3 | 0 | 3 |
| EXO5 | ZNF718 | 0.608926 | 5 | 0 | 4 |
| EXO5 | ZNF318 | 0.605835 | 4 | 0 | 3 |
For details and further investigation, click here
