| Full name: zyg-11 family member A, cell cycle regulator | Alias Symbol: ZYG11 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 440590 | HGNC ID: HGNC:32058 | Ensembl Gene: ENSG00000203995 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZYG11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZYG11A | 440590 | 231517_at | 1.0628 | 0.2300 | |
| GSE26886 | ZYG11A | 440590 | 231517_at | -0.7215 | 0.0533 | |
| GSE45670 | ZYG11A | 440590 | 231517_at | -0.1955 | 0.5045 | |
| GSE53622 | ZYG11A | 440590 | 51484 | 0.3733 | 0.0407 | |
| GSE53624 | ZYG11A | 440590 | 34313 | -0.1174 | 0.6313 | |
| GSE63941 | ZYG11A | 440590 | 231517_at | 1.3710 | 0.1486 | |
| GSE77861 | ZYG11A | 440590 | 231517_at | -0.1413 | 0.3029 | |
| GSE97050 | ZYG11A | 440590 | A_33_P3256490 | 0.1996 | 0.5541 | |
| SRP007169 | ZYG11A | 440590 | RNAseq | -0.8942 | 0.2039 | |
| SRP064894 | ZYG11A | 440590 | RNAseq | -0.4310 | 0.2341 | |
| SRP133303 | ZYG11A | 440590 | RNAseq | 0.7178 | 0.0217 | |
| SRP159526 | ZYG11A | 440590 | RNAseq | 0.1333 | 0.7995 | |
| SRP193095 | ZYG11A | 440590 | RNAseq | 0.1554 | 0.4275 | |
| SRP219564 | ZYG11A | 440590 | RNAseq | -0.5868 | 0.3986 | |
| TCGA | ZYG11A | 440590 | RNAseq | 2.4165 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZYG11A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZYG11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZYG11A | 440590 | 3 | 4 | 23 | |
| GSE20123 | ZYG11A | 440590 | 3 | 3 | 24 | |
| GSE43470 | ZYG11A | 440590 | 5 | 2 | 36 | |
| GSE46452 | ZYG11A | 440590 | 2 | 1 | 56 | |
| GSE47630 | ZYG11A | 440590 | 8 | 4 | 28 | |
| GSE54993 | ZYG11A | 440590 | 0 | 1 | 69 | |
| GSE54994 | ZYG11A | 440590 | 11 | 2 | 40 | |
| GSE60625 | ZYG11A | 440590 | 0 | 0 | 11 | |
| GSE74703 | ZYG11A | 440590 | 4 | 1 | 31 | |
| GSE74704 | ZYG11A | 440590 | 2 | 0 | 18 | |
| TCGA | ZYG11A | 440590 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of ZYG11A:
Generating mutation plots.
Highly correlated genes for ZYG11A:
Showing top 20/181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZYG11A | PITRM1 | 0.731016 | 3 | 0 | 3 |
| ZYG11A | SNRPE | 0.727235 | 3 | 0 | 3 |
| ZYG11A | ZNF616 | 0.717416 | 3 | 0 | 3 |
| ZYG11A | GAR1 | 0.712234 | 3 | 0 | 3 |
| ZYG11A | SCFD1 | 0.710625 | 3 | 0 | 3 |
| ZYG11A | ZNF606 | 0.708996 | 3 | 0 | 3 |
| ZYG11A | BAG6 | 0.708776 | 3 | 0 | 3 |
| ZYG11A | OSTC | 0.707081 | 3 | 0 | 3 |
| ZYG11A | SPATA2 | 0.697197 | 3 | 0 | 3 |
| ZYG11A | POGK | 0.695174 | 3 | 0 | 3 |
| ZYG11A | ZNF165 | 0.688872 | 3 | 0 | 3 |
| ZYG11A | BLCAP | 0.685814 | 3 | 0 | 3 |
| ZYG11A | RBM4B | 0.675674 | 3 | 0 | 3 |
| ZYG11A | TAS2R4 | 0.668407 | 3 | 0 | 3 |
| ZYG11A | MMACHC | 0.663441 | 4 | 0 | 4 |
| ZYG11A | RCHY1 | 0.662999 | 4 | 0 | 4 |
| ZYG11A | MRPS12 | 0.662159 | 3 | 0 | 3 |
| ZYG11A | ZNF485 | 0.661813 | 3 | 0 | 3 |
| ZYG11A | ARFGAP2 | 0.659289 | 3 | 0 | 3 |
| ZYG11A | ZNF432 | 0.659024 | 4 | 0 | 4 |
For details and further investigation, click here
