| Full name: beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | Alias Symbol: beta3Gal-T3|galT3|P1|GLOB | ||
| Type: protein-coding gene | Cytoband: 3q26.1 | ||
| Entrez ID: 8706 | HGNC ID: HGNC:918 | Ensembl Gene: ENSG00000169255 | OMIM ID: 603094 |
| Drug and gene relationship at DGIdb | |||
Expression of B3GALNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GALNT1 | 8706 | 223374_s_at | 0.4689 | 0.6019 | |
| GSE20347 | B3GALNT1 | 8706 | 211812_s_at | 0.2301 | 0.0534 | |
| GSE23400 | B3GALNT1 | 8706 | 211812_s_at | 0.1202 | 0.0062 | |
| GSE26886 | B3GALNT1 | 8706 | 223374_s_at | -1.0198 | 0.0393 | |
| GSE29001 | B3GALNT1 | 8706 | 211379_x_at | 0.9266 | 0.1279 | |
| GSE38129 | B3GALNT1 | 8706 | 211379_x_at | 0.4829 | 0.0401 | |
| GSE45670 | B3GALNT1 | 8706 | 223374_s_at | -0.2591 | 0.6059 | |
| GSE53622 | B3GALNT1 | 8706 | 104117 | 0.2132 | 0.0837 | |
| GSE53624 | B3GALNT1 | 8706 | 104117 | 0.1598 | 0.1931 | |
| GSE63941 | B3GALNT1 | 8706 | 223374_s_at | -2.3617 | 0.1623 | |
| GSE77861 | B3GALNT1 | 8706 | 211812_s_at | -0.1287 | 0.6512 | |
| GSE97050 | B3GALNT1 | 8706 | A_23_P41166 | 0.1991 | 0.3291 | |
| SRP007169 | B3GALNT1 | 8706 | RNAseq | -0.1148 | 0.8506 | |
| SRP008496 | B3GALNT1 | 8706 | RNAseq | 0.2566 | 0.5473 | |
| SRP064894 | B3GALNT1 | 8706 | RNAseq | 0.3530 | 0.1631 | |
| SRP133303 | B3GALNT1 | 8706 | RNAseq | 0.3775 | 0.2011 | |
| SRP159526 | B3GALNT1 | 8706 | RNAseq | 0.9115 | 0.0404 | |
| SRP193095 | B3GALNT1 | 8706 | RNAseq | 0.0808 | 0.6709 | |
| SRP219564 | B3GALNT1 | 8706 | RNAseq | -0.1076 | 0.7960 | |
| TCGA | B3GALNT1 | 8706 | RNAseq | -0.2888 | 0.0176 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by B3GALNT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GALNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GALNT1 | 8706 | 22 | 0 | 8 | |
| GSE20123 | B3GALNT1 | 8706 | 22 | 0 | 8 | |
| GSE43470 | B3GALNT1 | 8706 | 23 | 0 | 20 | |
| GSE46452 | B3GALNT1 | 8706 | 18 | 2 | 39 | |
| GSE47630 | B3GALNT1 | 8706 | 19 | 3 | 18 | |
| GSE54993 | B3GALNT1 | 8706 | 1 | 11 | 58 | |
| GSE54994 | B3GALNT1 | 8706 | 38 | 1 | 14 | |
| GSE60625 | B3GALNT1 | 8706 | 0 | 6 | 5 | |
| GSE74703 | B3GALNT1 | 8706 | 20 | 0 | 16 | |
| GSE74704 | B3GALNT1 | 8706 | 14 | 0 | 6 | |
| TCGA | B3GALNT1 | 8706 | 77 | 0 | 19 |
Total number of gains: 254; Total number of losses: 23; Total Number of normals: 211.
Somatic mutations of B3GALNT1:
Generating mutation plots.
Highly correlated genes for B3GALNT1:
Showing top 20/292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GALNT1 | LRRC34 | 0.741195 | 3 | 0 | 3 |
| B3GALNT1 | BCAR3 | 0.726195 | 3 | 0 | 3 |
| B3GALNT1 | ZBTB1 | 0.695188 | 3 | 0 | 3 |
| B3GALNT1 | ZFAND4 | 0.688341 | 3 | 0 | 3 |
| B3GALNT1 | CDAN1 | 0.681707 | 3 | 0 | 3 |
| B3GALNT1 | GPKOW | 0.67339 | 3 | 0 | 3 |
| B3GALNT1 | ERCC6 | 0.67104 | 3 | 0 | 3 |
| B3GALNT1 | TRAPPC3 | 0.665717 | 3 | 0 | 3 |
| B3GALNT1 | MRPS18C | 0.659904 | 3 | 0 | 3 |
| B3GALNT1 | ITPRIPL2 | 0.65332 | 4 | 0 | 3 |
| B3GALNT1 | ZNF564 | 0.649249 | 3 | 0 | 3 |
| B3GALNT1 | PARP11 | 0.645705 | 3 | 0 | 3 |
| B3GALNT1 | ZACN | 0.639437 | 3 | 0 | 3 |
| B3GALNT1 | NOC3L | 0.638356 | 4 | 0 | 4 |
| B3GALNT1 | COX7A2L | 0.638286 | 4 | 0 | 4 |
| B3GALNT1 | EXO5 | 0.636666 | 4 | 0 | 3 |
| B3GALNT1 | ATG16L2 | 0.636074 | 4 | 0 | 3 |
| B3GALNT1 | ZNF436 | 0.63256 | 3 | 0 | 3 |
| B3GALNT1 | OSTC | 0.629444 | 3 | 0 | 3 |
| B3GALNT1 | ZNF485 | 0.628424 | 4 | 0 | 3 |
For details and further investigation, click here
