| Full name: zinc finger protein 684 | Alias Symbol: MGC27466 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 127396 | HGNC ID: HGNC:28418 | Ensembl Gene: ENSG00000117010 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF684:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF684 | 127396 | 232563_at | 0.1546 | 0.8540 | |
| GSE26886 | ZNF684 | 127396 | 244398_x_at | 0.2273 | 0.1786 | |
| GSE45670 | ZNF684 | 127396 | 244398_x_at | 0.0832 | 0.4978 | |
| GSE53622 | ZNF684 | 127396 | 93305 | 0.1135 | 0.1053 | |
| GSE53624 | ZNF684 | 127396 | 93305 | 0.2873 | 0.0000 | |
| GSE63941 | ZNF684 | 127396 | 232563_at | 0.1468 | 0.7918 | |
| GSE77861 | ZNF684 | 127396 | 244398_x_at | -0.0482 | 0.6798 | |
| GSE97050 | ZNF684 | 127396 | A_33_P3211054 | -0.0045 | 0.9848 | |
| SRP007169 | ZNF684 | 127396 | RNAseq | 0.5382 | 0.4112 | |
| SRP064894 | ZNF684 | 127396 | RNAseq | 0.3355 | 0.0754 | |
| SRP133303 | ZNF684 | 127396 | RNAseq | 0.5704 | 0.0013 | |
| SRP159526 | ZNF684 | 127396 | RNAseq | 0.7268 | 0.2188 | |
| SRP193095 | ZNF684 | 127396 | RNAseq | 0.2737 | 0.0769 | |
| SRP219564 | ZNF684 | 127396 | RNAseq | 0.5026 | 0.2794 | |
| TCGA | ZNF684 | 127396 | RNAseq | -0.3427 | 0.0057 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF684 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF684:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF684 | 127396 | 3 | 4 | 23 | |
| GSE20123 | ZNF684 | 127396 | 2 | 3 | 25 | |
| GSE43470 | ZNF684 | 127396 | 7 | 2 | 34 | |
| GSE46452 | ZNF684 | 127396 | 4 | 1 | 54 | |
| GSE47630 | ZNF684 | 127396 | 9 | 2 | 29 | |
| GSE54993 | ZNF684 | 127396 | 0 | 1 | 69 | |
| GSE54994 | ZNF684 | 127396 | 13 | 2 | 38 | |
| GSE60625 | ZNF684 | 127396 | 0 | 0 | 11 | |
| GSE74703 | ZNF684 | 127396 | 6 | 1 | 29 | |
| GSE74704 | ZNF684 | 127396 | 1 | 0 | 19 | |
| TCGA | ZNF684 | 127396 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of ZNF684:
Generating mutation plots.
Highly correlated genes for ZNF684:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF684 | CLEC12B | 0.77735 | 3 | 0 | 3 |
| ZNF684 | FSIP1 | 0.70435 | 3 | 0 | 3 |
| ZNF684 | SUDS3 | 0.699539 | 3 | 0 | 3 |
| ZNF684 | MAGEB2 | 0.691232 | 3 | 0 | 3 |
| ZNF684 | NUBP1 | 0.651044 | 3 | 0 | 3 |
| ZNF684 | SF3A3 | 0.646574 | 4 | 0 | 3 |
| ZNF684 | EXO5 | 0.618953 | 4 | 0 | 3 |
| ZNF684 | PLCL2 | 0.614266 | 3 | 0 | 3 |
| ZNF684 | ZFP69 | 0.599572 | 5 | 0 | 3 |
| ZNF684 | MID1 | 0.593966 | 4 | 0 | 3 |
| ZNF684 | POC1A | 0.589863 | 5 | 0 | 4 |
| ZNF684 | PXN-AS1 | 0.589645 | 3 | 0 | 3 |
| ZNF684 | ZNF511 | 0.588255 | 4 | 0 | 3 |
| ZNF684 | DCTPP1 | 0.578658 | 3 | 0 | 3 |
| ZNF684 | POLE4 | 0.578063 | 5 | 0 | 3 |
| ZNF684 | ZNF311 | 0.574584 | 3 | 0 | 3 |
| ZNF684 | LENG1 | 0.574409 | 4 | 0 | 3 |
| ZNF684 | NDC1 | 0.571595 | 5 | 0 | 3 |
| ZNF684 | TMEM39B | 0.567087 | 4 | 0 | 3 |
| ZNF684 | CDC20 | 0.565794 | 5 | 0 | 3 |
For details and further investigation, click here
