| Full name: small nuclear ribonucleoprotein D3 polypeptide | Alias Symbol: SMD3|Sm-D3 | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 6634 | HGNC ID: HGNC:11160 | Ensembl Gene: ENSG00000100028 | OMIM ID: 601062 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRPD3 | 6634 | 202567_at | 0.4335 | 0.2782 | |
| GSE20347 | SNRPD3 | 6634 | 202567_at | -0.0124 | 0.9407 | |
| GSE23400 | SNRPD3 | 6634 | 202567_at | 0.4104 | 0.0000 | |
| GSE26886 | SNRPD3 | 6634 | 202567_at | 0.1721 | 0.3141 | |
| GSE29001 | SNRPD3 | 6634 | 202567_at | 0.2397 | 0.2631 | |
| GSE38129 | SNRPD3 | 6634 | 202567_at | 0.3146 | 0.0392 | |
| GSE45670 | SNRPD3 | 6634 | 202567_at | 0.3301 | 0.0022 | |
| GSE53622 | SNRPD3 | 6634 | 14667 | 0.2984 | 0.0000 | |
| GSE53624 | SNRPD3 | 6634 | 14667 | 0.5170 | 0.0000 | |
| GSE63941 | SNRPD3 | 6634 | 202567_at | 0.5807 | 0.2279 | |
| GSE77861 | SNRPD3 | 6634 | 202567_at | 0.1068 | 0.6785 | |
| GSE97050 | SNRPD3 | 6634 | A_33_P3396239 | 0.0735 | 0.8020 | |
| SRP007169 | SNRPD3 | 6634 | RNAseq | 0.1101 | 0.7195 | |
| SRP008496 | SNRPD3 | 6634 | RNAseq | 0.2206 | 0.3124 | |
| SRP064894 | SNRPD3 | 6634 | RNAseq | 0.5291 | 0.0194 | |
| SRP133303 | SNRPD3 | 6634 | RNAseq | 0.0287 | 0.8121 | |
| SRP159526 | SNRPD3 | 6634 | RNAseq | 0.4468 | 0.0066 | |
| SRP193095 | SNRPD3 | 6634 | RNAseq | 0.0119 | 0.9291 | |
| SRP219564 | SNRPD3 | 6634 | RNAseq | 0.2483 | 0.4718 | |
| TCGA | SNRPD3 | 6634 | RNAseq | 0.2291 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRPD3 | 6634 | 5 | 7 | 18 | |
| GSE20123 | SNRPD3 | 6634 | 5 | 6 | 19 | |
| GSE43470 | SNRPD3 | 6634 | 3 | 6 | 34 | |
| GSE46452 | SNRPD3 | 6634 | 32 | 1 | 26 | |
| GSE47630 | SNRPD3 | 6634 | 8 | 5 | 27 | |
| GSE54993 | SNRPD3 | 6634 | 3 | 6 | 61 | |
| GSE54994 | SNRPD3 | 6634 | 11 | 7 | 35 | |
| GSE60625 | SNRPD3 | 6634 | 5 | 0 | 6 | |
| GSE74703 | SNRPD3 | 6634 | 3 | 5 | 28 | |
| GSE74704 | SNRPD3 | 6634 | 2 | 3 | 15 | |
| TCGA | SNRPD3 | 6634 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of SNRPD3:
Generating mutation plots.
Highly correlated genes for SNRPD3:
Showing top 20/684 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRPD3 | ELOF1 | 0.812051 | 3 | 0 | 3 |
| SNRPD3 | STX10 | 0.805333 | 3 | 0 | 3 |
| SNRPD3 | MRI1 | 0.795355 | 3 | 0 | 3 |
| SNRPD3 | RNFT2 | 0.791321 | 3 | 0 | 3 |
| SNRPD3 | EARS2 | 0.77772 | 3 | 0 | 3 |
| SNRPD3 | KANSL2 | 0.770828 | 3 | 0 | 3 |
| SNRPD3 | INTS10 | 0.750734 | 3 | 0 | 3 |
| SNRPD3 | INPP5B | 0.749812 | 3 | 0 | 3 |
| SNRPD3 | GLE1 | 0.746725 | 3 | 0 | 3 |
| SNRPD3 | MMACHC | 0.736991 | 3 | 0 | 3 |
| SNRPD3 | SEPHS1 | 0.735704 | 3 | 0 | 3 |
| SNRPD3 | SLC37A3 | 0.716677 | 3 | 0 | 3 |
| SNRPD3 | SDHAF2 | 0.715446 | 3 | 0 | 3 |
| SNRPD3 | RPUSD2 | 0.714941 | 3 | 0 | 3 |
| SNRPD3 | KIAA2013 | 0.710369 | 3 | 0 | 3 |
| SNRPD3 | ZNF79 | 0.707932 | 3 | 0 | 3 |
| SNRPD3 | KIF3A | 0.707567 | 3 | 0 | 3 |
| SNRPD3 | NPLOC4 | 0.706146 | 3 | 0 | 3 |
| SNRPD3 | DNPEP | 0.70424 | 3 | 0 | 3 |
| SNRPD3 | ZC3HC1 | 0.699652 | 3 | 0 | 3 |
For details and further investigation, click here
