ZNF140

 

Full name: zinc finger protein 140 Alias Symbol: pHZ-39
Type: protein-coding gene Cytoband: 12q24.33
Entrez ID: 7699 HGNC ID: HGNC:12925 Ensembl Gene: ENSG00000196387 OMIM ID: 604082
Drug and gene relationship at DGIdb

 

Expression of ZNF140:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF140 7699 204523_at -0.0556 0.9664
GSE20347 ZNF140 7699 204523_at -0.2098 0.3872
GSE23400 ZNF140 7699 204523_at 0.0898 0.1782
GSE26886 ZNF140 7699 204523_at 0.3909 0.2367
GSE29001 ZNF140 7699 204523_at -0.0701 0.9097
GSE38129 ZNF140 7699 204523_at -0.0577 0.7163
GSE45670 ZNF140 7699 204523_at 0.0080 0.9631
GSE63941 ZNF140 7699 204523_at -0.7294 0.3881
GSE77861 ZNF140 7699 204523_at -0.0683 0.8016
GSE97050 ZNF140 7699 A_33_P3237393 -0.0114 0.9624
SRP007169 ZNF140 7699 RNAseq -0.3140 0.5368
SRP008496 ZNF140 7699 RNAseq 0.2413 0.4616
SRP064894 ZNF140 7699 RNAseq -0.0850 0.5293
SRP133303 ZNF140 7699 RNAseq -0.2764 0.3457
SRP159526 ZNF140 7699 RNAseq 0.0180 0.9626
SRP193095 ZNF140 7699 RNAseq -0.2775 0.0003
SRP219564 ZNF140 7699 RNAseq -0.3881 0.1447
TCGA ZNF140 7699 RNAseq -0.1218 0.0608

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF140 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF140:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF140 7699 4 5 21
GSE20123 ZNF140 7699 4 5 21
GSE43470 ZNF140 7699 3 3 37
GSE46452 ZNF140 7699 8 3 48
GSE47630 ZNF140 7699 9 3 28
GSE54993 ZNF140 7699 0 6 64
GSE54994 ZNF140 7699 4 8 41
GSE60625 ZNF140 7699 1 0 10
GSE74703 ZNF140 7699 2 3 31
GSE74704 ZNF140 7699 2 3 15
TCGA ZNF140 7699 21 15 60

Total number of gains: 58; Total number of losses: 54; Total Number of normals: 376.  


 

Somatic mutations of ZNF140:

 

Generating mutation plots.

 

Highly correlated genes for ZNF140:

 

Showing top 20/360 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF140ELF20.830251303
ZNF140ARID20.807276303
ZNF140NOM10.785197303
ZNF140C2orf760.752844303
ZNF140DFFA0.746681303
ZNF140ZNF75A0.743464303
ZNF140SPA170.739712303
ZNF140ZNF2020.736765303
ZNF140RBAK0.736039303
ZNF140EFCAB70.735381303
ZNF140TMEM1680.729806403
ZNF140NUB10.727071303
ZNF140RAB280.724636303
ZNF140ZNF2680.7187091008
ZNF140CEBPG0.717736303
ZNF140ZNF354A0.71481303
ZNF140BIVM0.71451303
ZNF140PAN30.713223303
ZNF140ZBED50.711232303
ZNF140ZNF70.710764303

For details and further investigation, click here