| Full name: exo/endonuclease G | Alias Symbol: ENGL-a|ENGL|ENGL-b | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 9941 | HGNC ID: HGNC:3347 | Ensembl Gene: ENSG00000157036 | OMIM ID: 604051 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EXOG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXOG | 9941 | 205521_at | 0.1769 | 0.6710 | |
| GSE20347 | EXOG | 9941 | 205521_at | 0.1962 | 0.1398 | |
| GSE23400 | EXOG | 9941 | 205521_at | 0.0820 | 0.0653 | |
| GSE26886 | EXOG | 9941 | 205521_at | 0.0437 | 0.8732 | |
| GSE29001 | EXOG | 9941 | 205521_at | 0.1873 | 0.4128 | |
| GSE38129 | EXOG | 9941 | 205521_at | 0.0935 | 0.3758 | |
| GSE45670 | EXOG | 9941 | 205521_at | 0.4263 | 0.0031 | |
| GSE53622 | EXOG | 9941 | 131137 | 0.4680 | 0.0000 | |
| GSE53624 | EXOG | 9941 | 131137 | 0.3644 | 0.0001 | |
| GSE63941 | EXOG | 9941 | 205521_at | -1.3131 | 0.0080 | |
| GSE77861 | EXOG | 9941 | 206903_at | -0.0872 | 0.5331 | |
| GSE97050 | EXOG | 9941 | A_33_P3406706 | 0.1347 | 0.6238 | |
| SRP007169 | EXOG | 9941 | RNAseq | 1.0884 | 0.0545 | |
| SRP008496 | EXOG | 9941 | RNAseq | 0.7734 | 0.0650 | |
| SRP064894 | EXOG | 9941 | RNAseq | 0.4422 | 0.0088 | |
| SRP133303 | EXOG | 9941 | RNAseq | 0.1312 | 0.2336 | |
| SRP159526 | EXOG | 9941 | RNAseq | 0.1652 | 0.4921 | |
| SRP193095 | EXOG | 9941 | RNAseq | 0.2017 | 0.0443 | |
| SRP219564 | EXOG | 9941 | RNAseq | -0.0578 | 0.8757 | |
| TCGA | EXOG | 9941 | RNAseq | -0.1761 | 0.0156 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EXOG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXOG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXOG | 9941 | 0 | 19 | 11 | |
| GSE20123 | EXOG | 9941 | 0 | 19 | 11 | |
| GSE43470 | EXOG | 9941 | 0 | 20 | 23 | |
| GSE46452 | EXOG | 9941 | 2 | 17 | 40 | |
| GSE47630 | EXOG | 9941 | 1 | 25 | 14 | |
| GSE54993 | EXOG | 9941 | 6 | 3 | 61 | |
| GSE54994 | EXOG | 9941 | 0 | 34 | 19 | |
| GSE60625 | EXOG | 9941 | 5 | 0 | 6 | |
| GSE74703 | EXOG | 9941 | 0 | 16 | 20 | |
| GSE74704 | EXOG | 9941 | 0 | 13 | 7 | |
| TCGA | EXOG | 9941 | 1 | 71 | 24 |
Total number of gains: 15; Total number of losses: 237; Total Number of normals: 236.
Somatic mutations of EXOG:
Generating mutation plots.
Highly correlated genes for EXOG:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXOG | DCDC1 | 0.807776 | 3 | 0 | 3 |
| EXOG | ZNF763 | 0.77449 | 4 | 0 | 3 |
| EXOG | ZNF843 | 0.773486 | 3 | 0 | 3 |
| EXOG | YY2 | 0.767526 | 3 | 0 | 3 |
| EXOG | TAS2R31 | 0.766861 | 3 | 0 | 3 |
| EXOG | CHST10 | 0.766735 | 4 | 0 | 4 |
| EXOG | FAM71F1 | 0.756593 | 4 | 0 | 4 |
| EXOG | KLF17 | 0.754023 | 3 | 0 | 3 |
| EXOG | KRTAP10-12 | 0.750339 | 3 | 0 | 3 |
| EXOG | FFAR1 | 0.749436 | 3 | 0 | 3 |
| EXOG | BBC3 | 0.740388 | 3 | 0 | 3 |
| EXOG | TAS2R30 | 0.738263 | 3 | 0 | 3 |
| EXOG | OR2T1 | 0.737641 | 3 | 0 | 3 |
| EXOG | FAM131A | 0.737312 | 3 | 0 | 3 |
| EXOG | ZNF527 | 0.73286 | 5 | 0 | 5 |
| EXOG | TMEM179 | 0.732433 | 4 | 0 | 4 |
| EXOG | USP51 | 0.728814 | 5 | 0 | 5 |
| EXOG | OR2T27 | 0.726221 | 3 | 0 | 3 |
| EXOG | DEFB128 | 0.723098 | 3 | 0 | 3 |
| EXOG | ST8SIA1 | 0.721476 | 4 | 0 | 3 |
For details and further investigation, click here
