| Full name: carbohydrate sulfotransferase 10 | Alias Symbol: HNK-1ST | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 9486 | HGNC ID: HGNC:19650 | Ensembl Gene: ENSG00000115526 | OMIM ID: 606376 |
| Drug and gene relationship at DGIdb | |||
Expression of CHST10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHST10 | 9486 | 204065_at | 0.0024 | 0.9967 | |
| GSE20347 | CHST10 | 9486 | 204065_at | 0.2741 | 0.0403 | |
| GSE23400 | CHST10 | 9486 | 204065_at | 0.0153 | 0.7875 | |
| GSE26886 | CHST10 | 9486 | 204065_at | 0.7444 | 0.0004 | |
| GSE29001 | CHST10 | 9486 | 204065_at | 0.1915 | 0.3904 | |
| GSE38129 | CHST10 | 9486 | 204065_at | 0.1234 | 0.3976 | |
| GSE45670 | CHST10 | 9486 | 204065_at | 0.1212 | 0.5026 | |
| GSE53622 | CHST10 | 9486 | 27772 | 0.3519 | 0.0001 | |
| GSE53624 | CHST10 | 9486 | 27772 | 0.2125 | 0.0147 | |
| GSE63941 | CHST10 | 9486 | 204065_at | -0.1326 | 0.8030 | |
| GSE77861 | CHST10 | 9486 | 204065_at | 0.2209 | 0.1124 | |
| GSE97050 | CHST10 | 9486 | A_23_P102351 | 0.0826 | 0.6611 | |
| SRP064894 | CHST10 | 9486 | RNAseq | 1.0233 | 0.0002 | |
| SRP133303 | CHST10 | 9486 | RNAseq | 0.5299 | 0.0244 | |
| SRP159526 | CHST10 | 9486 | RNAseq | 1.5844 | 0.0000 | |
| SRP193095 | CHST10 | 9486 | RNAseq | 1.0818 | 0.0000 | |
| SRP219564 | CHST10 | 9486 | RNAseq | 0.4367 | 0.5639 | |
| TCGA | CHST10 | 9486 | RNAseq | -0.0563 | 0.7553 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CHST10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHST10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHST10 | 9486 | 5 | 2 | 23 | |
| GSE20123 | CHST10 | 9486 | 5 | 2 | 23 | |
| GSE43470 | CHST10 | 9486 | 4 | 1 | 38 | |
| GSE46452 | CHST10 | 9486 | 2 | 3 | 54 | |
| GSE47630 | CHST10 | 9486 | 7 | 0 | 33 | |
| GSE54993 | CHST10 | 9486 | 0 | 6 | 64 | |
| GSE54994 | CHST10 | 9486 | 10 | 0 | 43 | |
| GSE60625 | CHST10 | 9486 | 0 | 3 | 8 | |
| GSE74703 | CHST10 | 9486 | 4 | 1 | 31 | |
| GSE74704 | CHST10 | 9486 | 3 | 1 | 16 | |
| TCGA | CHST10 | 9486 | 33 | 6 | 57 |
Total number of gains: 73; Total number of losses: 25; Total Number of normals: 390.
Somatic mutations of CHST10:
Generating mutation plots.
Highly correlated genes for CHST10:
Showing top 20/447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHST10 | DCDC1 | 0.868315 | 3 | 0 | 3 |
| CHST10 | TMEM105 | 0.846677 | 3 | 0 | 3 |
| CHST10 | STRC | 0.838933 | 3 | 0 | 3 |
| CHST10 | CNOT3 | 0.836023 | 3 | 0 | 3 |
| CHST10 | CLDN9 | 0.832831 | 3 | 0 | 3 |
| CHST10 | FFAR1 | 0.821789 | 3 | 0 | 3 |
| CHST10 | OR2T1 | 0.819951 | 3 | 0 | 3 |
| CHST10 | BBC3 | 0.810325 | 3 | 0 | 3 |
| CHST10 | GJD4 | 0.807396 | 3 | 0 | 3 |
| CHST10 | SLC22A11 | 0.802728 | 3 | 0 | 3 |
| CHST10 | C19orf71 | 0.801074 | 3 | 0 | 3 |
| CHST10 | TTC12 | 0.801034 | 3 | 0 | 3 |
| CHST10 | C2CD4D | 0.799717 | 3 | 0 | 3 |
| CHST10 | HOXC9 | 0.799517 | 3 | 0 | 3 |
| CHST10 | KATNAL2 | 0.796102 | 3 | 0 | 3 |
| CHST10 | MRGPRG | 0.793556 | 3 | 0 | 3 |
| CHST10 | OR2T27 | 0.793162 | 3 | 0 | 3 |
| CHST10 | PLA2G2C | 0.792724 | 3 | 0 | 3 |
| CHST10 | PRLH | 0.792671 | 3 | 0 | 3 |
| CHST10 | OR2A5 | 0.791343 | 3 | 0 | 3 |
For details and further investigation, click here
