| Full name: transmembrane protein 179 | Alias Symbol: FLJ42486|TMEM179A | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 388021 | HGNC ID: HGNC:20137 | Ensembl Gene: ENSG00000258986 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMEM179:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM179 | 388021 | 231216_at | 0.1301 | 0.6508 | |
| GSE26886 | TMEM179 | 388021 | 231216_at | 0.3384 | 0.0110 | |
| GSE45670 | TMEM179 | 388021 | 231216_at | 0.0651 | 0.5266 | |
| GSE53622 | TMEM179 | 388021 | 50214 | 0.3825 | 0.0000 | |
| GSE53624 | TMEM179 | 388021 | 50214 | 0.4086 | 0.0002 | |
| GSE63941 | TMEM179 | 388021 | 231216_at | -0.0157 | 0.9248 | |
| GSE77861 | TMEM179 | 388021 | 231216_at | -0.1685 | 0.2020 | |
| GSE97050 | TMEM179 | 388021 | A_24_P93206 | 0.2106 | 0.3073 | |
| TCGA | TMEM179 | 388021 | RNAseq | -1.8357 | 0.1433 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM179 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM179:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM179 | 388021 | 11 | 3 | 16 | |
| GSE20123 | TMEM179 | 388021 | 10 | 2 | 18 | |
| GSE43470 | TMEM179 | 388021 | 6 | 4 | 33 | |
| GSE46452 | TMEM179 | 388021 | 19 | 4 | 36 | |
| GSE47630 | TMEM179 | 388021 | 10 | 8 | 22 | |
| GSE54993 | TMEM179 | 388021 | 4 | 10 | 56 | |
| GSE54994 | TMEM179 | 388021 | 21 | 4 | 28 | |
| GSE60625 | TMEM179 | 388021 | 0 | 2 | 9 | |
| GSE74703 | TMEM179 | 388021 | 5 | 3 | 28 | |
| GSE74704 | TMEM179 | 388021 | 5 | 2 | 13 | |
| TCGA | TMEM179 | 388021 | 32 | 19 | 45 |
Total number of gains: 123; Total number of losses: 61; Total Number of normals: 304.
Somatic mutations of TMEM179:
Generating mutation plots.
Highly correlated genes for TMEM179:
Showing top 20/435 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM179 | NPEPL1 | 0.811813 | 3 | 0 | 3 |
| TMEM179 | PSMB11 | 0.796321 | 3 | 0 | 3 |
| TMEM179 | TOR2A | 0.79626 | 3 | 0 | 3 |
| TMEM179 | SCN2B | 0.793728 | 3 | 0 | 3 |
| TMEM179 | MAG | 0.791856 | 4 | 0 | 4 |
| TMEM179 | WFDC3 | 0.788646 | 3 | 0 | 3 |
| TMEM179 | TSPAN32 | 0.787524 | 3 | 0 | 3 |
| TMEM179 | C2CD4D | 0.786015 | 3 | 0 | 3 |
| TMEM179 | DCDC1 | 0.780868 | 3 | 0 | 3 |
| TMEM179 | ROM1 | 0.777052 | 3 | 0 | 3 |
| TMEM179 | TERT | 0.776534 | 3 | 0 | 3 |
| TMEM179 | FOXB1 | 0.776215 | 4 | 0 | 4 |
| TMEM179 | SPEF1 | 0.774747 | 3 | 0 | 3 |
| TMEM179 | CRYGA | 0.77134 | 3 | 0 | 3 |
| TMEM179 | GZMM | 0.768187 | 3 | 0 | 3 |
| TMEM179 | USHBP1 | 0.767857 | 3 | 0 | 3 |
| TMEM179 | OPRD1 | 0.764593 | 3 | 0 | 3 |
| TMEM179 | GRIN2C | 0.761314 | 3 | 0 | 3 |
| TMEM179 | TNNI2 | 0.761033 | 3 | 0 | 3 |
| TMEM179 | OR5A1 | 0.756912 | 3 | 0 | 3 |
For details and further investigation, click here
