| Full name: family with sequence similarity 131 member A | Alias Symbol: MGC21688 | ||
| Type: protein-coding gene | Cytoband: 3q27.1 | ||
| Entrez ID: 131408 | HGNC ID: HGNC:28308 | Ensembl Gene: ENSG00000175182 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM131A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM131A | 131408 | 221904_at | -0.0753 | 0.9246 | |
| GSE20347 | FAM131A | 131408 | 221904_at | 0.5904 | 0.0052 | |
| GSE23400 | FAM131A | 131408 | 221904_at | 0.2973 | 0.0002 | |
| GSE26886 | FAM131A | 131408 | 221904_at | 0.7724 | 0.0007 | |
| GSE29001 | FAM131A | 131408 | 221904_at | 0.4209 | 0.1360 | |
| GSE38129 | FAM131A | 131408 | 221904_at | 0.4207 | 0.0138 | |
| GSE45670 | FAM131A | 131408 | 221904_at | 0.2256 | 0.4453 | |
| GSE53622 | FAM131A | 131408 | 53092 | 0.1762 | 0.0179 | |
| GSE53624 | FAM131A | 131408 | 53092 | 0.1462 | 0.0890 | |
| GSE63941 | FAM131A | 131408 | 221904_at | 0.2795 | 0.6293 | |
| GSE77861 | FAM131A | 131408 | 221904_at | 0.7660 | 0.0020 | |
| GSE97050 | FAM131A | 131408 | A_23_P41204 | -0.0364 | 0.9219 | |
| SRP007169 | FAM131A | 131408 | RNAseq | 1.1463 | 0.0488 | |
| SRP008496 | FAM131A | 131408 | RNAseq | 0.8867 | 0.0107 | |
| SRP064894 | FAM131A | 131408 | RNAseq | 0.1736 | 0.4326 | |
| SRP133303 | FAM131A | 131408 | RNAseq | 0.6394 | 0.0000 | |
| SRP159526 | FAM131A | 131408 | RNAseq | 1.0302 | 0.0041 | |
| SRP193095 | FAM131A | 131408 | RNAseq | 0.8989 | 0.0000 | |
| SRP219564 | FAM131A | 131408 | RNAseq | -0.1409 | 0.7500 | |
| TCGA | FAM131A | 131408 | RNAseq | 0.0309 | 0.7057 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAM131A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM131A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM131A | 131408 | 25 | 0 | 5 | |
| GSE20123 | FAM131A | 131408 | 25 | 0 | 5 | |
| GSE43470 | FAM131A | 131408 | 25 | 0 | 18 | |
| GSE46452 | FAM131A | 131408 | 19 | 1 | 39 | |
| GSE47630 | FAM131A | 131408 | 27 | 2 | 11 | |
| GSE54993 | FAM131A | 131408 | 1 | 19 | 50 | |
| GSE54994 | FAM131A | 131408 | 41 | 0 | 12 | |
| GSE60625 | FAM131A | 131408 | 0 | 6 | 5 | |
| GSE74703 | FAM131A | 131408 | 21 | 0 | 15 | |
| GSE74704 | FAM131A | 131408 | 17 | 0 | 3 | |
| TCGA | FAM131A | 131408 | 77 | 0 | 19 |
Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.
Somatic mutations of FAM131A:
Generating mutation plots.
Highly correlated genes for FAM131A:
Showing top 20/399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM131A | SLC22A7 | 0.841778 | 3 | 0 | 3 |
| FAM131A | FOXE3 | 0.829804 | 3 | 0 | 3 |
| FAM131A | MRGPRG | 0.813371 | 3 | 0 | 3 |
| FAM131A | KCNH3 | 0.811426 | 3 | 0 | 3 |
| FAM131A | YY2 | 0.802411 | 3 | 0 | 3 |
| FAM131A | NPPB | 0.802219 | 3 | 0 | 3 |
| FAM131A | DCDC1 | 0.792391 | 3 | 0 | 3 |
| FAM131A | STRC | 0.791064 | 3 | 0 | 3 |
| FAM131A | C19orf71 | 0.781493 | 3 | 0 | 3 |
| FAM131A | GRIK4 | 0.780465 | 3 | 0 | 3 |
| FAM131A | C9orf153 | 0.779699 | 3 | 0 | 3 |
| FAM131A | C2CD4D | 0.776905 | 3 | 0 | 3 |
| FAM131A | CIB3 | 0.775016 | 3 | 0 | 3 |
| FAM131A | FOXB1 | 0.767747 | 3 | 0 | 3 |
| FAM131A | CRYGA | 0.767456 | 3 | 0 | 3 |
| FAM131A | GRIK5 | 0.765659 | 3 | 0 | 3 |
| FAM131A | AQP8 | 0.764772 | 3 | 0 | 3 |
| FAM131A | OR2T1 | 0.759653 | 3 | 0 | 3 |
| FAM131A | BBC3 | 0.758717 | 3 | 0 | 3 |
| FAM131A | PLA2G2C | 0.757302 | 3 | 0 | 3 |
For details and further investigation, click here
