| Full name: family with sequence similarity 174 member B | Alias Symbol: LOC400451|MGC102891 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 400451 | HGNC ID: HGNC:34339 | Ensembl Gene: ENSG00000185442 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM174B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM174B | 400451 | 221880_s_at | 0.0135 | 0.9891 | |
| GSE20347 | FAM174B | 400451 | 221880_s_at | -0.4430 | 0.0004 | |
| GSE23400 | FAM174B | 400451 | 221880_s_at | -0.1531 | 0.0006 | |
| GSE26886 | FAM174B | 400451 | 221880_s_at | -0.5039 | 0.1228 | |
| GSE29001 | FAM174B | 400451 | 221880_s_at | -0.7387 | 0.0131 | |
| GSE38129 | FAM174B | 400451 | 221880_s_at | -0.3453 | 0.0208 | |
| GSE45670 | FAM174B | 400451 | 221880_s_at | -0.5599 | 0.0004 | |
| GSE53622 | FAM174B | 400451 | 5665 | -1.2472 | 0.0000 | |
| GSE53624 | FAM174B | 400451 | 5665 | -1.3352 | 0.0000 | |
| GSE63941 | FAM174B | 400451 | 221880_s_at | 0.2485 | 0.7443 | |
| GSE77861 | FAM174B | 400451 | 221880_s_at | -0.0761 | 0.6934 | |
| GSE97050 | FAM174B | 400451 | A_23_P100001 | -0.3902 | 0.3961 | |
| SRP007169 | FAM174B | 400451 | RNAseq | -3.8519 | 0.0000 | |
| SRP008496 | FAM174B | 400451 | RNAseq | -3.1995 | 0.0000 | |
| SRP064894 | FAM174B | 400451 | RNAseq | -1.5774 | 0.0000 | |
| SRP133303 | FAM174B | 400451 | RNAseq | -1.4855 | 0.0000 | |
| SRP159526 | FAM174B | 400451 | RNAseq | -0.1632 | 0.6640 | |
| SRP193095 | FAM174B | 400451 | RNAseq | -1.6441 | 0.0000 | |
| SRP219564 | FAM174B | 400451 | RNAseq | -0.3455 | 0.5801 | |
| TCGA | FAM174B | 400451 | RNAseq | -1.0192 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by FAM174B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM174B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM174B | 400451 | 8 | 2 | 20 | |
| GSE20123 | FAM174B | 400451 | 8 | 2 | 20 | |
| GSE43470 | FAM174B | 400451 | 4 | 4 | 35 | |
| GSE46452 | FAM174B | 400451 | 3 | 7 | 49 | |
| GSE47630 | FAM174B | 400451 | 8 | 11 | 21 | |
| GSE54993 | FAM174B | 400451 | 4 | 6 | 60 | |
| GSE54994 | FAM174B | 400451 | 7 | 7 | 39 | |
| GSE60625 | FAM174B | 400451 | 4 | 0 | 7 | |
| GSE74703 | FAM174B | 400451 | 3 | 3 | 30 | |
| GSE74704 | FAM174B | 400451 | 3 | 3 | 14 | |
| TCGA | FAM174B | 400451 | 18 | 13 | 65 |
Total number of gains: 70; Total number of losses: 58; Total Number of normals: 360.
Somatic mutations of FAM174B:
Generating mutation plots.
Highly correlated genes for FAM174B:
Showing top 20/573 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM174B | ZNF347 | 0.696525 | 3 | 0 | 3 |
| FAM174B | SLC10A5 | 0.66196 | 3 | 0 | 3 |
| FAM174B | RGS7BP | 0.65744 | 4 | 0 | 4 |
| FAM174B | C9orf152 | 0.649155 | 6 | 0 | 6 |
| FAM174B | INPP5B | 0.646775 | 4 | 0 | 3 |
| FAM174B | USP24 | 0.645391 | 3 | 0 | 3 |
| FAM174B | SLC43A1 | 0.643421 | 3 | 0 | 3 |
| FAM174B | ABHD16A | 0.639831 | 3 | 0 | 3 |
| FAM174B | RABL3 | 0.638266 | 3 | 0 | 3 |
| FAM174B | EPHA7 | 0.63442 | 3 | 0 | 3 |
| FAM174B | SKI | 0.632483 | 5 | 0 | 4 |
| FAM174B | LMBRD1 | 0.632002 | 7 | 0 | 5 |
| FAM174B | ZNF662 | 0.631298 | 6 | 0 | 5 |
| FAM174B | PPM1L | 0.630368 | 6 | 0 | 6 |
| FAM174B | GFRA1 | 0.629494 | 4 | 0 | 4 |
| FAM174B | CCDC28A | 0.629064 | 7 | 0 | 5 |
| FAM174B | NEIL1 | 0.622055 | 3 | 0 | 3 |
| FAM174B | KPNA3 | 0.620439 | 3 | 0 | 3 |
| FAM174B | TXNDC16 | 0.619973 | 4 | 0 | 3 |
| FAM174B | ZNF626 | 0.617181 | 3 | 0 | 3 |
For details and further investigation, click here
