| Full name: SKI proto-oncogene | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.33-p36.32 | ||
| Entrez ID: 6497 | HGNC ID: HGNC:10896 | Ensembl Gene: ENSG00000157933 | OMIM ID: 164780 |
| Drug and gene relationship at DGIdb | |||
Expression of SKI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SKI | 6497 | 229265_at | 0.3161 | 0.6072 | |
| GSE20347 | SKI | 6497 | 204270_at | -0.5014 | 0.0010 | |
| GSE29001 | SKI | 6497 | 204270_at | -0.0348 | 0.9691 | |
| GSE45670 | SKI | 6497 | 229265_at | -0.4227 | 0.0071 | |
| GSE53622 | SKI | 6497 | 164952 | -0.0034 | 0.9752 | |
| GSE53624 | SKI | 6497 | 164952 | 0.2542 | 0.0002 | |
| GSE63941 | SKI | 6497 | 229265_at | -1.2147 | 0.0285 | |
| GSE77861 | SKI | 6497 | 229265_at | -0.3444 | 0.1044 | |
| GSE97050 | SKI | 6497 | A_23_P325631 | -0.2721 | 0.3176 | |
| SRP007169 | SKI | 6497 | RNAseq | 0.1879 | 0.6993 | |
| SRP008496 | SKI | 6497 | RNAseq | 0.8061 | 0.0166 | |
| SRP064894 | SKI | 6497 | RNAseq | 0.0568 | 0.8117 | |
| SRP133303 | SKI | 6497 | RNAseq | -0.1600 | 0.3267 | |
| SRP159526 | SKI | 6497 | RNAseq | 0.3791 | 0.3468 | |
| SRP193095 | SKI | 6497 | RNAseq | 0.3670 | 0.0097 | |
| SRP219564 | SKI | 6497 | RNAseq | -0.0867 | 0.8397 | |
| TCGA | SKI | 6497 | RNAseq | -0.0754 | 0.0904 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SKI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SKI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SKI | 6497 | 4 | 7 | 19 | |
| GSE20123 | SKI | 6497 | 4 | 6 | 20 | |
| GSE43470 | SKI | 6497 | 3 | 5 | 35 | |
| GSE46452 | SKI | 6497 | 7 | 1 | 51 | |
| GSE47630 | SKI | 6497 | 8 | 4 | 28 | |
| GSE54993 | SKI | 6497 | 2 | 2 | 66 | |
| GSE54994 | SKI | 6497 | 15 | 2 | 36 | |
| GSE60625 | SKI | 6497 | 0 | 0 | 11 | |
| GSE74703 | SKI | 6497 | 3 | 3 | 30 | |
| GSE74704 | SKI | 6497 | 4 | 0 | 16 | |
| TCGA | SKI | 6497 | 14 | 20 | 62 |
Total number of gains: 64; Total number of losses: 50; Total Number of normals: 374.
Somatic mutations of SKI:
Generating mutation plots.
Highly correlated genes for SKI:
Showing top 20/318 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SKI | UBP1 | 0.847859 | 3 | 0 | 3 |
| SKI | ADCK1 | 0.839738 | 3 | 0 | 3 |
| SKI | ZXDA | 0.785779 | 3 | 0 | 3 |
| SKI | ZNF445 | 0.766743 | 3 | 0 | 3 |
| SKI | TCF7L1 | 0.748084 | 3 | 0 | 3 |
| SKI | BAG6 | 0.736483 | 5 | 0 | 5 |
| SKI | BCL9 | 0.732926 | 3 | 0 | 3 |
| SKI | ZNF784 | 0.728458 | 3 | 0 | 3 |
| SKI | TMCO4 | 0.728426 | 3 | 0 | 3 |
| SKI | EXOSC10 | 0.72548 | 3 | 0 | 3 |
| SKI | NFASC | 0.725175 | 3 | 0 | 3 |
| SKI | PACRGL | 0.723036 | 4 | 0 | 4 |
| SKI | MRAS | 0.722728 | 5 | 0 | 4 |
| SKI | DMAP1 | 0.721281 | 4 | 0 | 3 |
| SKI | LRRC34 | 0.718096 | 3 | 0 | 3 |
| SKI | DHX30 | 0.715302 | 4 | 0 | 3 |
| SKI | FIBIN | 0.714456 | 3 | 0 | 3 |
| SKI | LRRC47 | 0.712446 | 4 | 0 | 3 |
| SKI | MSL3 | 0.711937 | 3 | 0 | 3 |
| SKI | ERGIC1 | 0.710775 | 4 | 0 | 3 |
For details and further investigation, click here
