| Full name: thioredoxin domain containing 16 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q22.1 | ||
| Entrez ID: 57544 | HGNC ID: HGNC:19965 | Ensembl Gene: ENSG00000087301 | OMIM ID: 616179 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNDC16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC16 | 57544 | 226747_at | 0.1049 | 0.9343 | |
| GSE26886 | TXNDC16 | 57544 | 226747_at | 0.0004 | 0.9993 | |
| GSE45670 | TXNDC16 | 57544 | 226747_at | -0.5732 | 0.0270 | |
| GSE53622 | TXNDC16 | 57544 | 13821 | 0.0004 | 0.9972 | |
| GSE53624 | TXNDC16 | 57544 | 13821 | 0.1277 | 0.3257 | |
| GSE63941 | TXNDC16 | 57544 | 226747_at | -0.0917 | 0.9315 | |
| GSE77861 | TXNDC16 | 57544 | 226747_at | -0.0929 | 0.7152 | |
| GSE97050 | TXNDC16 | 57544 | A_23_P398836 | -0.0607 | 0.7695 | |
| SRP007169 | TXNDC16 | 57544 | RNAseq | 0.0026 | 0.9962 | |
| SRP008496 | TXNDC16 | 57544 | RNAseq | -0.0300 | 0.9392 | |
| SRP064894 | TXNDC16 | 57544 | RNAseq | -0.0214 | 0.9216 | |
| SRP133303 | TXNDC16 | 57544 | RNAseq | 0.1050 | 0.5767 | |
| SRP159526 | TXNDC16 | 57544 | RNAseq | 0.0277 | 0.9186 | |
| SRP193095 | TXNDC16 | 57544 | RNAseq | -0.2905 | 0.0427 | |
| SRP219564 | TXNDC16 | 57544 | RNAseq | 0.1837 | 0.6122 | |
| TCGA | TXNDC16 | 57544 | RNAseq | -0.2015 | 0.0364 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TXNDC16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC16 | 57544 | 8 | 3 | 19 | |
| GSE20123 | TXNDC16 | 57544 | 8 | 3 | 19 | |
| GSE43470 | TXNDC16 | 57544 | 9 | 1 | 33 | |
| GSE46452 | TXNDC16 | 57544 | 16 | 3 | 40 | |
| GSE47630 | TXNDC16 | 57544 | 11 | 10 | 19 | |
| GSE54993 | TXNDC16 | 57544 | 3 | 8 | 59 | |
| GSE54994 | TXNDC16 | 57544 | 19 | 4 | 30 | |
| GSE60625 | TXNDC16 | 57544 | 0 | 2 | 9 | |
| GSE74703 | TXNDC16 | 57544 | 8 | 1 | 27 | |
| GSE74704 | TXNDC16 | 57544 | 3 | 2 | 15 | |
| TCGA | TXNDC16 | 57544 | 34 | 12 | 50 |
Total number of gains: 119; Total number of losses: 49; Total Number of normals: 320.
Somatic mutations of TXNDC16:
Generating mutation plots.
Highly correlated genes for TXNDC16:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC16 | INPP5B | 0.784945 | 3 | 0 | 3 |
| TXNDC16 | ATXN7L3B | 0.77827 | 3 | 0 | 3 |
| TXNDC16 | LMBRD2 | 0.777089 | 3 | 0 | 3 |
| TXNDC16 | SP1 | 0.76853 | 3 | 0 | 3 |
| TXNDC16 | DDX50 | 0.763573 | 3 | 0 | 3 |
| TXNDC16 | SAE1 | 0.762269 | 3 | 0 | 3 |
| TXNDC16 | ANKRD50 | 0.76191 | 3 | 0 | 3 |
| TXNDC16 | MCCC1 | 0.755303 | 3 | 0 | 3 |
| TXNDC16 | PDE6D | 0.752904 | 3 | 0 | 3 |
| TXNDC16 | POLA1 | 0.738836 | 3 | 0 | 3 |
| TXNDC16 | C12orf43 | 0.733979 | 3 | 0 | 3 |
| TXNDC16 | CDC26 | 0.728608 | 3 | 0 | 3 |
| TXNDC16 | PCID2 | 0.727521 | 3 | 0 | 3 |
| TXNDC16 | CREBBP | 0.724138 | 3 | 0 | 3 |
| TXNDC16 | IPO8 | 0.721334 | 3 | 0 | 3 |
| TXNDC16 | APPL2 | 0.718701 | 3 | 0 | 3 |
| TXNDC16 | NUB1 | 0.718208 | 4 | 0 | 4 |
| TXNDC16 | GOLPH3 | 0.717513 | 3 | 0 | 3 |
| TXNDC16 | WEE1 | 0.717086 | 3 | 0 | 3 |
| TXNDC16 | FRS2 | 0.716895 | 3 | 0 | 3 |
For details and further investigation, click here
