| Full name: regulator of G protein signaling 7 binding protein | Alias Symbol: R7BP | ||
| Type: protein-coding gene | Cytoband: 5q12.3 | ||
| Entrez ID: 401190 | HGNC ID: HGNC:23271 | Ensembl Gene: ENSG00000186479 | OMIM ID: 610890 |
| Drug and gene relationship at DGIdb | |||
Expression of RGS7BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGS7BP | 401190 | 237719_x_at | -0.3583 | 0.1823 | |
| GSE26886 | RGS7BP | 401190 | 237719_x_at | -0.1312 | 0.2759 | |
| GSE45670 | RGS7BP | 401190 | 237719_x_at | -1.1308 | 0.0000 | |
| GSE53622 | RGS7BP | 401190 | 14608 | -1.8747 | 0.0000 | |
| GSE53624 | RGS7BP | 401190 | 14608 | -1.9019 | 0.0000 | |
| GSE63941 | RGS7BP | 401190 | 237719_x_at | 0.0641 | 0.6157 | |
| GSE77861 | RGS7BP | 401190 | 237719_x_at | -0.0476 | 0.5888 | |
| GSE97050 | RGS7BP | 401190 | A_33_P3379606 | -0.5466 | 0.2125 | |
| SRP133303 | RGS7BP | 401190 | RNAseq | -2.5179 | 0.0000 | |
| SRP159526 | RGS7BP | 401190 | RNAseq | -1.6461 | 0.0037 | |
| TCGA | RGS7BP | 401190 | RNAseq | -1.9575 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by RGS7BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGS7BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGS7BP | 401190 | 0 | 14 | 16 | |
| GSE20123 | RGS7BP | 401190 | 0 | 14 | 16 | |
| GSE43470 | RGS7BP | 401190 | 1 | 13 | 29 | |
| GSE46452 | RGS7BP | 401190 | 0 | 28 | 31 | |
| GSE47630 | RGS7BP | 401190 | 2 | 17 | 21 | |
| GSE54993 | RGS7BP | 401190 | 8 | 1 | 61 | |
| GSE54994 | RGS7BP | 401190 | 1 | 19 | 33 | |
| GSE60625 | RGS7BP | 401190 | 0 | 0 | 11 | |
| GSE74703 | RGS7BP | 401190 | 1 | 9 | 26 | |
| GSE74704 | RGS7BP | 401190 | 0 | 7 | 13 | |
| TCGA | RGS7BP | 401190 | 5 | 50 | 41 |
Total number of gains: 18; Total number of losses: 172; Total Number of normals: 298.
Somatic mutations of RGS7BP:
Generating mutation plots.
Highly correlated genes for RGS7BP:
Showing top 20/1162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGS7BP | CYP21A2 | 0.840941 | 3 | 0 | 3 |
| RGS7BP | CLEC3B | 0.832573 | 3 | 0 | 3 |
| RGS7BP | RCAN2 | 0.83174 | 5 | 0 | 5 |
| RGS7BP | ANGPTL1 | 0.827337 | 5 | 0 | 5 |
| RGS7BP | RNASE4 | 0.823171 | 3 | 0 | 3 |
| RGS7BP | CBX7 | 0.813668 | 5 | 0 | 5 |
| RGS7BP | TMOD1 | 0.811334 | 3 | 0 | 3 |
| RGS7BP | LRCH1 | 0.810882 | 3 | 0 | 3 |
| RGS7BP | UBXN10 | 0.810494 | 3 | 0 | 3 |
| RGS7BP | BHMT2 | 0.809348 | 5 | 0 | 5 |
| RGS7BP | ATP1A2 | 0.808336 | 5 | 0 | 5 |
| RGS7BP | PCP4 | 0.804079 | 5 | 0 | 5 |
| RGS7BP | CFD | 0.797037 | 5 | 0 | 5 |
| RGS7BP | OLFML1 | 0.795097 | 3 | 0 | 3 |
| RGS7BP | PDE1C | 0.79315 | 5 | 0 | 5 |
| RGS7BP | ABCA6 | 0.790161 | 5 | 0 | 5 |
| RGS7BP | SORCS1 | 0.788789 | 4 | 0 | 4 |
| RGS7BP | FHL5 | 0.78728 | 6 | 0 | 6 |
| RGS7BP | AR | 0.783282 | 5 | 0 | 5 |
| RGS7BP | CCDC69 | 0.782345 | 5 | 0 | 5 |
For details and further investigation, click here
