| Full name: coiled-coil domain containing 28A | Alias Symbol: CCRL1AP|DKFZp586D0623 | ||
| Type: protein-coding gene | Cytoband: 6q24.1 | ||
| Entrez ID: 25901 | HGNC ID: HGNC:21098 | Ensembl Gene: ENSG00000024862 | OMIM ID: 615353 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC28A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC28A | 25901 | 209479_at | -0.2554 | 0.5626 | |
| GSE20347 | CCDC28A | 25901 | 209479_at | -0.2379 | 0.1935 | |
| GSE23400 | CCDC28A | 25901 | 209479_at | -0.0108 | 0.8550 | |
| GSE26886 | CCDC28A | 25901 | 209479_at | -0.3010 | 0.2395 | |
| GSE29001 | CCDC28A | 25901 | 209479_at | -0.0362 | 0.9110 | |
| GSE38129 | CCDC28A | 25901 | 209479_at | -0.2105 | 0.2190 | |
| GSE45670 | CCDC28A | 25901 | 209479_at | -0.4126 | 0.0083 | |
| GSE53622 | CCDC28A | 25901 | 71798 | -0.3524 | 0.0000 | |
| GSE53624 | CCDC28A | 25901 | 71798 | -0.3641 | 0.0000 | |
| GSE63941 | CCDC28A | 25901 | 209479_at | 0.3336 | 0.4419 | |
| GSE77861 | CCDC28A | 25901 | 209479_at | -0.1774 | 0.3995 | |
| GSE97050 | CCDC28A | 25901 | A_23_P31085 | -0.2608 | 0.2408 | |
| SRP007169 | CCDC28A | 25901 | RNAseq | -1.1701 | 0.0063 | |
| SRP008496 | CCDC28A | 25901 | RNAseq | -1.0877 | 0.0000 | |
| SRP064894 | CCDC28A | 25901 | RNAseq | -0.3331 | 0.0677 | |
| SRP133303 | CCDC28A | 25901 | RNAseq | -0.2796 | 0.1240 | |
| SRP159526 | CCDC28A | 25901 | RNAseq | -0.2426 | 0.4582 | |
| SRP193095 | CCDC28A | 25901 | RNAseq | -0.6236 | 0.0000 | |
| SRP219564 | CCDC28A | 25901 | RNAseq | -0.4260 | 0.1581 | |
| TCGA | CCDC28A | 25901 | RNAseq | -0.2130 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CCDC28A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC28A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC28A | 25901 | 2 | 4 | 24 | |
| GSE20123 | CCDC28A | 25901 | 2 | 3 | 25 | |
| GSE43470 | CCDC28A | 25901 | 5 | 0 | 38 | |
| GSE46452 | CCDC28A | 25901 | 3 | 10 | 46 | |
| GSE47630 | CCDC28A | 25901 | 9 | 4 | 27 | |
| GSE54993 | CCDC28A | 25901 | 3 | 2 | 65 | |
| GSE54994 | CCDC28A | 25901 | 8 | 8 | 37 | |
| GSE60625 | CCDC28A | 25901 | 0 | 1 | 10 | |
| GSE74703 | CCDC28A | 25901 | 4 | 0 | 32 | |
| GSE74704 | CCDC28A | 25901 | 0 | 1 | 19 | |
| TCGA | CCDC28A | 25901 | 11 | 17 | 68 |
Total number of gains: 47; Total number of losses: 50; Total Number of normals: 391.
Somatic mutations of CCDC28A:
Generating mutation plots.
Highly correlated genes for CCDC28A:
Showing top 20/688 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC28A | UHRF2 | 0.737377 | 3 | 0 | 3 |
| CCDC28A | CNOT6L | 0.723598 | 7 | 0 | 7 |
| CCDC28A | ABI2 | 0.721354 | 3 | 0 | 3 |
| CCDC28A | ZBTB10 | 0.718302 | 4 | 0 | 4 |
| CCDC28A | MACROD2 | 0.712774 | 4 | 0 | 3 |
| CCDC28A | TMEM219 | 0.708206 | 4 | 0 | 4 |
| CCDC28A | LINC00938 | 0.699728 | 3 | 0 | 3 |
| CCDC28A | SRSF6 | 0.699402 | 3 | 0 | 3 |
| CCDC28A | FBXL3 | 0.695286 | 4 | 0 | 4 |
| CCDC28A | CBLL1 | 0.690595 | 4 | 0 | 3 |
| CCDC28A | PACSIN2 | 0.687646 | 3 | 0 | 3 |
| CCDC28A | PKN2 | 0.6871 | 3 | 0 | 3 |
| CCDC28A | ANXA3 | 0.685244 | 3 | 0 | 3 |
| CCDC28A | TERF2IP | 0.685175 | 3 | 0 | 3 |
| CCDC28A | MCPH1 | 0.685153 | 4 | 0 | 4 |
| CCDC28A | EXOC2 | 0.683907 | 3 | 0 | 3 |
| CCDC28A | AFF1 | 0.682929 | 5 | 0 | 4 |
| CCDC28A | PPFIBP2 | 0.682785 | 3 | 0 | 3 |
| CCDC28A | GABARAP | 0.682041 | 4 | 0 | 4 |
| CCDC28A | HDHD2 | 0.681877 | 4 | 0 | 3 |
For details and further investigation, click here
