| Full name: nei like DNA glycosylase 1 | Alias Symbol: FLJ22402|hFPG1|NEI1|FPG1 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 79661 | HGNC ID: HGNC:18448 | Ensembl Gene: ENSG00000140398 | OMIM ID: 608844 |
| Drug and gene relationship at DGIdb | |||
Expression of NEIL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | NEIL1 | 79661 | 3892 | -0.7762 | 0.0000 | |
| GSE53624 | NEIL1 | 79661 | 3892 | -1.1660 | 0.0000 | |
| GSE97050 | NEIL1 | 79661 | A_23_P129157 | -0.1695 | 0.4546 | |
| SRP064894 | NEIL1 | 79661 | RNAseq | -0.5373 | 0.0054 | |
| SRP133303 | NEIL1 | 79661 | RNAseq | -1.0361 | 0.0000 | |
| SRP159526 | NEIL1 | 79661 | RNAseq | 0.0362 | 0.8850 | |
| SRP193095 | NEIL1 | 79661 | RNAseq | -0.1231 | 0.5202 | |
| SRP219564 | NEIL1 | 79661 | RNAseq | -0.3217 | 0.5888 | |
| TCGA | NEIL1 | 79661 | RNAseq | -0.5192 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NEIL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEIL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEIL1 | 79661 | 8 | 1 | 21 | |
| GSE20123 | NEIL1 | 79661 | 8 | 1 | 21 | |
| GSE43470 | NEIL1 | 79661 | 4 | 6 | 33 | |
| GSE46452 | NEIL1 | 79661 | 3 | 7 | 49 | |
| GSE47630 | NEIL1 | 79661 | 8 | 10 | 22 | |
| GSE54993 | NEIL1 | 79661 | 5 | 6 | 59 | |
| GSE54994 | NEIL1 | 79661 | 5 | 6 | 42 | |
| GSE60625 | NEIL1 | 79661 | 4 | 0 | 7 | |
| GSE74703 | NEIL1 | 79661 | 4 | 3 | 29 | |
| GSE74704 | NEIL1 | 79661 | 4 | 1 | 15 | |
| TCGA | NEIL1 | 79661 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of NEIL1:
Generating mutation plots.
Highly correlated genes for NEIL1:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEIL1 | APPL1 | 0.739606 | 3 | 0 | 3 |
| NEIL1 | MAGI1 | 0.718681 | 3 | 0 | 3 |
| NEIL1 | BLOC1S1 | 0.709119 | 3 | 0 | 3 |
| NEIL1 | NCOA1 | 0.705489 | 3 | 0 | 3 |
| NEIL1 | PPM1L | 0.699654 | 3 | 0 | 3 |
| NEIL1 | SETD2 | 0.692644 | 3 | 0 | 3 |
| NEIL1 | GPD1L | 0.68822 | 3 | 0 | 3 |
| NEIL1 | CAB39L | 0.683911 | 3 | 0 | 3 |
| NEIL1 | ECHDC2 | 0.680482 | 3 | 0 | 3 |
| NEIL1 | TGFBR3 | 0.675718 | 3 | 0 | 3 |
| NEIL1 | ARL1 | 0.675113 | 3 | 0 | 3 |
| NEIL1 | PHKB | 0.67303 | 3 | 0 | 3 |
| NEIL1 | METTL7A | 0.671228 | 3 | 0 | 3 |
| NEIL1 | MTMR10 | 0.671056 | 3 | 0 | 3 |
| NEIL1 | RMND5B | 0.66709 | 3 | 0 | 3 |
| NEIL1 | PAIP2B | 0.666005 | 3 | 0 | 3 |
| NEIL1 | YPEL3 | 0.663854 | 3 | 0 | 3 |
| NEIL1 | ZMAT1 | 0.663714 | 3 | 0 | 3 |
| NEIL1 | DNAJA2 | 0.662362 | 3 | 0 | 3 |
| NEIL1 | SECISBP2L | 0.662295 | 3 | 0 | 3 |
For details and further investigation, click here
