| Full name: F-box and leucine rich repeat protein 20 | Alias Symbol: MGC15482|Fbl2|Fbl20 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 84961 | HGNC ID: HGNC:24679 | Ensembl Gene: ENSG00000108306 | OMIM ID: 609086 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXL20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXL20 | 84961 | 226842_at | -0.0779 | 0.8797 | |
| GSE26886 | FBXL20 | 84961 | 226842_at | 0.0361 | 0.8628 | |
| GSE45670 | FBXL20 | 84961 | 226842_at | -0.1955 | 0.3406 | |
| GSE53622 | FBXL20 | 84961 | 72436 | -0.0490 | 0.5704 | |
| GSE53624 | FBXL20 | 84961 | 107822 | -0.2691 | 0.0000 | |
| GSE63941 | FBXL20 | 84961 | 226842_at | -0.1242 | 0.8298 | |
| GSE77861 | FBXL20 | 84961 | 226842_at | 0.4959 | 0.0102 | |
| GSE97050 | FBXL20 | 84961 | A_33_P3333587 | -0.6121 | 0.0765 | |
| SRP007169 | FBXL20 | 84961 | RNAseq | 0.0992 | 0.8002 | |
| SRP008496 | FBXL20 | 84961 | RNAseq | 0.0042 | 0.9856 | |
| SRP064894 | FBXL20 | 84961 | RNAseq | -0.1342 | 0.3387 | |
| SRP133303 | FBXL20 | 84961 | RNAseq | -0.0144 | 0.9151 | |
| SRP159526 | FBXL20 | 84961 | RNAseq | 0.0537 | 0.8275 | |
| SRP193095 | FBXL20 | 84961 | RNAseq | -0.0061 | 0.9437 | |
| SRP219564 | FBXL20 | 84961 | RNAseq | -0.1506 | 0.4512 | |
| TCGA | FBXL20 | 84961 | RNAseq | -0.0477 | 0.4459 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXL20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXL20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXL20 | 84961 | 8 | 1 | 21 | |
| GSE20123 | FBXL20 | 84961 | 8 | 1 | 21 | |
| GSE43470 | FBXL20 | 84961 | 1 | 1 | 41 | |
| GSE46452 | FBXL20 | 84961 | 34 | 0 | 25 | |
| GSE47630 | FBXL20 | 84961 | 8 | 1 | 31 | |
| GSE54993 | FBXL20 | 84961 | 3 | 4 | 63 | |
| GSE54994 | FBXL20 | 84961 | 8 | 5 | 40 | |
| GSE60625 | FBXL20 | 84961 | 4 | 0 | 7 | |
| GSE74703 | FBXL20 | 84961 | 1 | 0 | 35 | |
| GSE74704 | FBXL20 | 84961 | 5 | 1 | 14 | |
| TCGA | FBXL20 | 84961 | 21 | 8 | 67 |
Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.
Somatic mutations of FBXL20:
Generating mutation plots.
Highly correlated genes for FBXL20:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXL20 | SUPT6H | 0.726419 | 3 | 0 | 3 |
| FBXL20 | PVALB | 0.724513 | 3 | 0 | 3 |
| FBXL20 | RASGRP4 | 0.652214 | 3 | 0 | 3 |
| FBXL20 | RTCB | 0.648684 | 3 | 0 | 3 |
| FBXL20 | SNAP25 | 0.646113 | 3 | 0 | 3 |
| FBXL20 | RNF44 | 0.638928 | 3 | 0 | 3 |
| FBXL20 | ERBB2 | 0.611666 | 4 | 0 | 3 |
| FBXL20 | ZFPM1 | 0.609281 | 3 | 0 | 3 |
| FBXL20 | HCK | 0.592775 | 3 | 0 | 3 |
| FBXL20 | JAKMIP2 | 0.576924 | 6 | 0 | 4 |
| FBXL20 | ACSF3 | 0.572843 | 3 | 0 | 3 |
| FBXL20 | PTCH1 | 0.548119 | 4 | 0 | 3 |
| FBXL20 | DCLK1 | 0.530586 | 5 | 0 | 3 |
| FBXL20 | DACH1 | 0.524647 | 6 | 0 | 4 |
For details and further investigation, click here
