| Full name: acyl-CoA synthetase family member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 197322 | HGNC ID: HGNC:27288 | Ensembl Gene: ENSG00000176715 | OMIM ID: 614245 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSF3 | 197322 | 227464_at | 0.0781 | 0.8678 | |
| GSE26886 | ACSF3 | 197322 | 227464_at | 0.4105 | 0.0004 | |
| GSE45670 | ACSF3 | 197322 | 227464_at | -0.0315 | 0.8431 | |
| GSE53622 | ACSF3 | 197322 | 35640 | 0.1513 | 0.0381 | |
| GSE53624 | ACSF3 | 197322 | 35640 | 0.1967 | 0.0375 | |
| GSE63941 | ACSF3 | 197322 | 1556552_a_at | -0.3355 | 0.5240 | |
| GSE77861 | ACSF3 | 197322 | 227464_at | 0.0029 | 0.9908 | |
| GSE97050 | ACSF3 | 197322 | A_23_P259797 | 0.1374 | 0.4663 | |
| SRP007169 | ACSF3 | 197322 | RNAseq | 0.3117 | 0.5648 | |
| SRP008496 | ACSF3 | 197322 | RNAseq | 0.9990 | 0.0233 | |
| SRP064894 | ACSF3 | 197322 | RNAseq | 0.5729 | 0.0565 | |
| SRP133303 | ACSF3 | 197322 | RNAseq | 0.2083 | 0.3836 | |
| SRP159526 | ACSF3 | 197322 | RNAseq | 0.6216 | 0.0315 | |
| SRP193095 | ACSF3 | 197322 | RNAseq | 0.3576 | 0.0134 | |
| SRP219564 | ACSF3 | 197322 | RNAseq | 0.4006 | 0.1687 | |
| TCGA | ACSF3 | 197322 | RNAseq | -0.0430 | 0.4563 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACSF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSF3 | 197322 | 4 | 3 | 23 | |
| GSE20123 | ACSF3 | 197322 | 4 | 3 | 23 | |
| GSE43470 | ACSF3 | 197322 | 1 | 13 | 29 | |
| GSE46452 | ACSF3 | 197322 | 38 | 1 | 20 | |
| GSE47630 | ACSF3 | 197322 | 11 | 9 | 20 | |
| GSE54993 | ACSF3 | 197322 | 3 | 4 | 63 | |
| GSE54994 | ACSF3 | 197322 | 9 | 11 | 33 | |
| GSE60625 | ACSF3 | 197322 | 4 | 0 | 7 | |
| GSE74703 | ACSF3 | 197322 | 1 | 9 | 26 | |
| GSE74704 | ACSF3 | 197322 | 3 | 2 | 15 | |
| TCGA | ACSF3 | 197322 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of ACSF3:
Generating mutation plots.
Highly correlated genes for ACSF3:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSF3 | LILRA3 | 0.742649 | 3 | 0 | 3 |
| ACSF3 | MSR1 | 0.714589 | 3 | 0 | 3 |
| ACSF3 | TUT1 | 0.709592 | 3 | 0 | 3 |
| ACSF3 | DPYSL4 | 0.703392 | 3 | 0 | 3 |
| ACSF3 | LINC00926 | 0.701162 | 3 | 0 | 3 |
| ACSF3 | FAM78A | 0.695569 | 3 | 0 | 3 |
| ACSF3 | DMP1 | 0.694816 | 3 | 0 | 3 |
| ACSF3 | ODF3B | 0.684983 | 4 | 0 | 4 |
| ACSF3 | ZNF366 | 0.678949 | 3 | 0 | 3 |
| ACSF3 | IGLL1 | 0.668279 | 4 | 0 | 4 |
| ACSF3 | LYG1 | 0.667848 | 3 | 0 | 3 |
| ACSF3 | DOCK2 | 0.66647 | 3 | 0 | 3 |
| ACSF3 | ITGA2B | 0.656657 | 4 | 0 | 3 |
| ACSF3 | ABCC6 | 0.655941 | 3 | 0 | 3 |
| ACSF3 | ZFPM1 | 0.651418 | 3 | 0 | 3 |
| ACSF3 | STK32C | 0.648614 | 3 | 0 | 3 |
| ACSF3 | TBC1D10C | 0.647964 | 3 | 0 | 3 |
| ACSF3 | TXNL4B | 0.647231 | 3 | 0 | 3 |
| ACSF3 | PCSK1N | 0.647026 | 3 | 0 | 3 |
| ACSF3 | CACNA1A | 0.645793 | 3 | 0 | 3 |
For details and further investigation, click here
