| Full name: SPT6 homolog, histone chaperone and transcription elongation factor | Alias Symbol: KIAA0162|SPT6H | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 6830 | HGNC ID: HGNC:11470 | Ensembl Gene: ENSG00000109111 | OMIM ID: 601333 |
| Drug and gene relationship at DGIdb | |||
Expression of SUPT6H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUPT6H | 6830 | 208420_x_at | 0.0164 | 0.9740 | |
| GSE20347 | SUPT6H | 6830 | 208420_x_at | 0.0739 | 0.5999 | |
| GSE23400 | SUPT6H | 6830 | 208420_x_at | 0.0034 | 0.9516 | |
| GSE26886 | SUPT6H | 6830 | 208420_x_at | 1.0822 | 0.0000 | |
| GSE29001 | SUPT6H | 6830 | 208420_x_at | -0.0225 | 0.9103 | |
| GSE38129 | SUPT6H | 6830 | 208420_x_at | -0.0054 | 0.9760 | |
| GSE45670 | SUPT6H | 6830 | 208831_x_at | 0.1186 | 0.4587 | |
| GSE53622 | SUPT6H | 6830 | 100774 | 0.3329 | 0.0000 | |
| GSE53624 | SUPT6H | 6830 | 109231 | 0.1098 | 0.0668 | |
| GSE63941 | SUPT6H | 6830 | 208420_x_at | 0.1706 | 0.6990 | |
| GSE77861 | SUPT6H | 6830 | 208831_x_at | 0.6472 | 0.0106 | |
| GSE97050 | SUPT6H | 6830 | A_23_P141479 | -0.2405 | 0.2969 | |
| SRP007169 | SUPT6H | 6830 | RNAseq | 1.2746 | 0.0024 | |
| SRP008496 | SUPT6H | 6830 | RNAseq | 1.0444 | 0.0002 | |
| SRP064894 | SUPT6H | 6830 | RNAseq | 0.1922 | 0.1611 | |
| SRP133303 | SUPT6H | 6830 | RNAseq | 0.2035 | 0.0933 | |
| SRP159526 | SUPT6H | 6830 | RNAseq | 0.1164 | 0.5277 | |
| SRP193095 | SUPT6H | 6830 | RNAseq | 0.3665 | 0.0001 | |
| SRP219564 | SUPT6H | 6830 | RNAseq | -0.1819 | 0.5438 | |
| TCGA | SUPT6H | 6830 | RNAseq | -0.0763 | 0.0555 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SUPT6H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUPT6H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUPT6H | 6830 | 9 | 1 | 20 | |
| GSE20123 | SUPT6H | 6830 | 9 | 1 | 20 | |
| GSE43470 | SUPT6H | 6830 | 0 | 1 | 42 | |
| GSE46452 | SUPT6H | 6830 | 33 | 1 | 25 | |
| GSE47630 | SUPT6H | 6830 | 7 | 1 | 32 | |
| GSE54993 | SUPT6H | 6830 | 2 | 3 | 65 | |
| GSE54994 | SUPT6H | 6830 | 7 | 6 | 40 | |
| GSE60625 | SUPT6H | 6830 | 4 | 0 | 7 | |
| GSE74703 | SUPT6H | 6830 | 0 | 1 | 35 | |
| GSE74704 | SUPT6H | 6830 | 7 | 1 | 12 | |
| TCGA | SUPT6H | 6830 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of SUPT6H:
Generating mutation plots.
Highly correlated genes for SUPT6H:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUPT6H | FBXL20 | 0.726419 | 3 | 0 | 3 |
| SUPT6H | CDC42EP2 | 0.718808 | 4 | 0 | 3 |
| SUPT6H | RILPL1 | 0.702383 | 3 | 0 | 3 |
| SUPT6H | PLBD2 | 0.685002 | 3 | 0 | 3 |
| SUPT6H | CHRM3 | 0.683535 | 3 | 0 | 3 |
| SUPT6H | SHISA4 | 0.674821 | 4 | 0 | 4 |
| SUPT6H | KCNN2 | 0.666625 | 3 | 0 | 3 |
| SUPT6H | CBX2 | 0.66361 | 3 | 0 | 3 |
| SUPT6H | WNT9A | 0.663345 | 3 | 0 | 3 |
| SUPT6H | SIPA1L1 | 0.656835 | 3 | 0 | 3 |
| SUPT6H | FBRSL1 | 0.651365 | 5 | 0 | 4 |
| SUPT6H | WRAP53 | 0.651249 | 4 | 0 | 4 |
| SUPT6H | MEF2C | 0.650914 | 3 | 0 | 3 |
| SUPT6H | TUT1 | 0.648224 | 4 | 0 | 4 |
| SUPT6H | RHOB | 0.646418 | 5 | 0 | 5 |
| SUPT6H | HOXC9 | 0.646059 | 4 | 0 | 3 |
| SUPT6H | NPW | 0.642889 | 3 | 0 | 3 |
| SUPT6H | SPP1 | 0.642788 | 3 | 0 | 3 |
| SUPT6H | LY6H | 0.642434 | 3 | 0 | 3 |
| SUPT6H | DYNC1I1 | 0.635754 | 4 | 0 | 3 |
For details and further investigation, click here
