FITM1

 

Full name: fat storage inducing transmembrane protein 1 Alias Symbol: FIT1
Type: protein-coding gene Cytoband: 14q12
Entrez ID: 161247 HGNC ID: HGNC:33714 Ensembl Gene: ENSG00000139914 OMIM ID: 612028
Drug and gene relationship at DGIdb

 

Expression of FITM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FITM1 161247 229567_at -0.1243 0.7455
GSE26886 FITM1 161247 229567_at -0.0762 0.5828
GSE45670 FITM1 161247 229567_at 0.1037 0.2804
GSE53622 FITM1 161247 20236 -0.0779 0.2573
GSE53624 FITM1 161247 20236 0.1854 0.0016
GSE63941 FITM1 161247 229567_at 0.1110 0.4663
GSE77861 FITM1 161247 229567_at 0.0234 0.8637
SRP219564 FITM1 161247 RNAseq 0.0375 0.9442
TCGA FITM1 161247 RNAseq -1.1143 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by FITM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FITM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FITM1 161247 8 3 19
GSE20123 FITM1 161247 8 3 19
GSE43470 FITM1 161247 8 2 33
GSE46452 FITM1 161247 16 2 41
GSE47630 FITM1 161247 11 10 19
GSE54993 FITM1 161247 3 11 56
GSE54994 FITM1 161247 18 5 30
GSE60625 FITM1 161247 0 2 9
GSE74703 FITM1 161247 7 2 27
GSE74704 FITM1 161247 3 2 15
TCGA FITM1 161247 27 13 56

Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.  

 

Somatic mutations of FITM1:

 

Generating mutation plots.

 

Highly correlated genes for FITM1:

 

Showing all 15 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FITM1ADAM330.649821303
FITM1GPR880.607552303
FITM1LINC011650.592004404
FITM1AMHR20.579585303
FITM1FAM170B-AS10.563818404
FITM1KRTAP5-AS10.562436303
FITM1CELA10.560364403
FITM1MAGEB30.548349303
FITM1HIPK40.548148403
FITM1RBM12B-AS10.538556603
FITM1CYP19A10.537674403
FITM1BEST10.526656303
FITM1CRH0.522238303
FITM1EPHA50.514881403
FITM1ERN20.505761403

For details and further investigation, click here