| Full name: ADAM metallopeptidase domain 33 | Alias Symbol: DKFZp434K0521|dJ964F7.1 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 80332 | HGNC ID: HGNC:15478 | Ensembl Gene: ENSG00000149451 | OMIM ID: 607114 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAM33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAM33 | 80332 | 233868_x_at | -0.5528 | 0.1194 | |
| GSE26886 | ADAM33 | 80332 | 233868_x_at | 0.0266 | 0.9024 | |
| GSE45670 | ADAM33 | 80332 | 233868_x_at | -0.3747 | 0.0052 | |
| GSE53622 | ADAM33 | 80332 | 64547 | -0.4214 | 0.0000 | |
| GSE53624 | ADAM33 | 80332 | 64547 | -0.2796 | 0.0014 | |
| GSE63941 | ADAM33 | 80332 | 233868_x_at | -0.4582 | 0.0060 | |
| GSE77861 | ADAM33 | 80332 | 233868_x_at | 0.2776 | 0.2196 | |
| GSE97050 | ADAM33 | 80332 | A_33_P3342653 | -0.6079 | 0.1255 | |
| SRP064894 | ADAM33 | 80332 | RNAseq | -1.1977 | 0.0053 | |
| SRP133303 | ADAM33 | 80332 | RNAseq | -2.0375 | 0.0000 | |
| SRP159526 | ADAM33 | 80332 | RNAseq | -1.7523 | 0.0000 | |
| SRP193095 | ADAM33 | 80332 | RNAseq | 0.8825 | 0.0041 | |
| SRP219564 | ADAM33 | 80332 | RNAseq | -1.6861 | 0.0370 | |
| TCGA | ADAM33 | 80332 | RNAseq | -1.1834 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ADAM33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAM33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAM33 | 80332 | 12 | 3 | 15 | |
| GSE20123 | ADAM33 | 80332 | 13 | 3 | 14 | |
| GSE43470 | ADAM33 | 80332 | 10 | 1 | 32 | |
| GSE46452 | ADAM33 | 80332 | 26 | 1 | 32 | |
| GSE47630 | ADAM33 | 80332 | 18 | 4 | 18 | |
| GSE54993 | ADAM33 | 80332 | 2 | 14 | 54 | |
| GSE54994 | ADAM33 | 80332 | 24 | 2 | 27 | |
| GSE60625 | ADAM33 | 80332 | 0 | 0 | 11 | |
| GSE74703 | ADAM33 | 80332 | 9 | 1 | 26 | |
| GSE74704 | ADAM33 | 80332 | 8 | 1 | 11 | |
| TCGA | ADAM33 | 80332 | 39 | 11 | 46 |
Total number of gains: 161; Total number of losses: 41; Total Number of normals: 286.
Somatic mutations of ADAM33:
Generating mutation plots.
Highly correlated genes for ADAM33:
Showing top 20/226 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAM33 | CMBL | 0.750926 | 3 | 0 | 3 |
| ADAM33 | ABCA9 | 0.710828 | 3 | 0 | 3 |
| ADAM33 | SRPK3 | 0.689608 | 4 | 0 | 4 |
| ADAM33 | PGLYRP2 | 0.685833 | 3 | 0 | 3 |
| ADAM33 | KRTAP6-3 | 0.681961 | 3 | 0 | 3 |
| ADAM33 | HRC | 0.68132 | 4 | 0 | 3 |
| ADAM33 | DYRK1B | 0.680779 | 3 | 0 | 3 |
| ADAM33 | FAM13C | 0.677636 | 3 | 0 | 3 |
| ADAM33 | RYR2 | 0.673485 | 4 | 0 | 4 |
| ADAM33 | TMEM174 | 0.670037 | 4 | 0 | 3 |
| ADAM33 | ANKDD1A | 0.664504 | 5 | 0 | 4 |
| ADAM33 | PLIN4 | 0.663281 | 3 | 0 | 3 |
| ADAM33 | DOCK3 | 0.660012 | 4 | 0 | 3 |
| ADAM33 | NPTN-IT1 | 0.659049 | 3 | 0 | 3 |
| ADAM33 | ZBTB20 | 0.65771 | 4 | 0 | 4 |
| ADAM33 | CCL16 | 0.657397 | 5 | 0 | 3 |
| ADAM33 | GKAP1 | 0.656051 | 4 | 0 | 3 |
| ADAM33 | CCDC152 | 0.652476 | 4 | 0 | 4 |
| ADAM33 | FITM1 | 0.649821 | 3 | 0 | 3 |
| ADAM33 | SRRM3 | 0.63965 | 4 | 0 | 3 |
For details and further investigation, click here
