| Full name: homeodomain interacting protein kinase 4 | Alias Symbol: FLJ32818 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 147746 | HGNC ID: HGNC:19007 | Ensembl Gene: ENSG00000160396 | OMIM ID: 611712 |
| Drug and gene relationship at DGIdb | |||
Expression of HIPK4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HIPK4 | 147746 | 1553238_a_at | -0.0950 | 0.6876 | |
| GSE26886 | HIPK4 | 147746 | 1553238_a_at | -0.0856 | 0.3660 | |
| GSE45670 | HIPK4 | 147746 | 1553238_a_at | 0.0832 | 0.3193 | |
| GSE53622 | HIPK4 | 147746 | 74099 | -0.4914 | 0.0001 | |
| GSE53624 | HIPK4 | 147746 | 74099 | -0.6450 | 0.0000 | |
| GSE63941 | HIPK4 | 147746 | 1553238_a_at | 0.2726 | 0.0233 | |
| GSE77861 | HIPK4 | 147746 | 1553238_a_at | -0.0655 | 0.5399 | |
| TCGA | HIPK4 | 147746 | RNAseq | -1.2101 | 0.0026 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HIPK4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HIPK4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HIPK4 | 147746 | 6 | 5 | 19 | |
| GSE20123 | HIPK4 | 147746 | 6 | 4 | 20 | |
| GSE43470 | HIPK4 | 147746 | 3 | 9 | 31 | |
| GSE46452 | HIPK4 | 147746 | 48 | 1 | 10 | |
| GSE47630 | HIPK4 | 147746 | 9 | 5 | 26 | |
| GSE54993 | HIPK4 | 147746 | 17 | 3 | 50 | |
| GSE54994 | HIPK4 | 147746 | 8 | 9 | 36 | |
| GSE60625 | HIPK4 | 147746 | 9 | 0 | 2 | |
| GSE74703 | HIPK4 | 147746 | 3 | 6 | 27 | |
| GSE74704 | HIPK4 | 147746 | 6 | 2 | 12 | |
| TCGA | HIPK4 | 147746 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 60; Total Number of normals: 299.
Somatic mutations of HIPK4:
Generating mutation plots.
Highly correlated genes for HIPK4:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HIPK4 | LINC01101 | 0.636306 | 3 | 0 | 3 |
| HIPK4 | LINC00841 | 0.629028 | 3 | 0 | 3 |
| HIPK4 | SPNS3 | 0.603794 | 4 | 0 | 3 |
| HIPK4 | LINC01260 | 0.603022 | 4 | 0 | 4 |
| HIPK4 | NHLRC4 | 0.602524 | 4 | 0 | 3 |
| HIPK4 | DGCR10 | 0.593432 | 4 | 0 | 3 |
| HIPK4 | CD300LG | 0.59182 | 5 | 0 | 4 |
| HIPK4 | IGDCC3 | 0.587817 | 4 | 0 | 3 |
| HIPK4 | POU2F2 | 0.583414 | 3 | 0 | 3 |
| HIPK4 | DIRAS1 | 0.576631 | 3 | 0 | 3 |
| HIPK4 | TTC16 | 0.571721 | 3 | 0 | 3 |
| HIPK4 | C20orf173 | 0.568317 | 3 | 0 | 3 |
| HIPK4 | KLKB1 | 0.566084 | 3 | 0 | 3 |
| HIPK4 | RNF31 | 0.562337 | 4 | 0 | 3 |
| HIPK4 | WFDC8 | 0.561894 | 4 | 0 | 3 |
| HIPK4 | LINC00687 | 0.559429 | 3 | 0 | 3 |
| HIPK4 | FOXN4 | 0.556557 | 4 | 0 | 3 |
| HIPK4 | BCAN | 0.551432 | 4 | 0 | 3 |
| HIPK4 | ZNF28 | 0.549752 | 3 | 0 | 3 |
| HIPK4 | FITM1 | 0.548148 | 4 | 0 | 3 |
For details and further investigation, click here
