| Full name: FLT3 interacting zinc finger 1 | Alias Symbol: FLJ14768|ZNF798 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 84922 | HGNC ID: HGNC:25917 | Ensembl Gene: ENSG00000179943 | OMIM ID: 609133 |
| Drug and gene relationship at DGIdb | |||
Expression of FIZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FIZ1 | 84922 | 226967_at | 0.1437 | 0.6619 | |
| GSE26886 | FIZ1 | 84922 | 226967_at | -0.1221 | 0.5878 | |
| GSE45670 | FIZ1 | 84922 | 226967_at | 0.0554 | 0.6482 | |
| GSE53622 | FIZ1 | 84922 | 120551 | 0.3435 | 0.0000 | |
| GSE53624 | FIZ1 | 84922 | 120551 | 0.3883 | 0.0000 | |
| GSE63941 | FIZ1 | 84922 | 226967_at | 1.1728 | 0.0000 | |
| GSE77861 | FIZ1 | 84922 | 226967_at | -0.0855 | 0.5939 | |
| GSE97050 | FIZ1 | 84922 | A_23_P107855 | 0.3496 | 0.2510 | |
| SRP007169 | FIZ1 | 84922 | RNAseq | -0.1236 | 0.8086 | |
| SRP008496 | FIZ1 | 84922 | RNAseq | -0.2996 | 0.3544 | |
| SRP064894 | FIZ1 | 84922 | RNAseq | 0.6878 | 0.0075 | |
| SRP133303 | FIZ1 | 84922 | RNAseq | 0.2762 | 0.0954 | |
| SRP159526 | FIZ1 | 84922 | RNAseq | 0.9855 | 0.0220 | |
| SRP193095 | FIZ1 | 84922 | RNAseq | 0.1316 | 0.3572 | |
| SRP219564 | FIZ1 | 84922 | RNAseq | 0.1780 | 0.6629 | |
| TCGA | FIZ1 | 84922 | RNAseq | -0.0876 | 0.1115 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FIZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FIZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FIZ1 | 84922 | 3 | 4 | 23 | |
| GSE20123 | FIZ1 | 84922 | 3 | 3 | 24 | |
| GSE43470 | FIZ1 | 84922 | 3 | 9 | 31 | |
| GSE46452 | FIZ1 | 84922 | 45 | 1 | 13 | |
| GSE47630 | FIZ1 | 84922 | 8 | 6 | 26 | |
| GSE54993 | FIZ1 | 84922 | 17 | 4 | 49 | |
| GSE54994 | FIZ1 | 84922 | 4 | 13 | 36 | |
| GSE60625 | FIZ1 | 84922 | 9 | 0 | 2 | |
| GSE74703 | FIZ1 | 84922 | 3 | 6 | 27 | |
| GSE74704 | FIZ1 | 84922 | 3 | 1 | 16 | |
| TCGA | FIZ1 | 84922 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.
Somatic mutations of FIZ1:
Generating mutation plots.
Highly correlated genes for FIZ1:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FIZ1 | RAB11B | 0.702477 | 3 | 0 | 3 |
| FIZ1 | ZNF384 | 0.702245 | 3 | 0 | 3 |
| FIZ1 | ANHX | 0.700114 | 4 | 0 | 4 |
| FIZ1 | PEX5L | 0.698578 | 3 | 0 | 3 |
| FIZ1 | PRAMEF11 | 0.695887 | 3 | 0 | 3 |
| FIZ1 | GTPBP3 | 0.691969 | 3 | 0 | 3 |
| FIZ1 | CABIN1 | 0.690351 | 3 | 0 | 3 |
| FIZ1 | AP2A1 | 0.687346 | 3 | 0 | 3 |
| FIZ1 | SLC34A3 | 0.686991 | 3 | 0 | 3 |
| FIZ1 | STX5 | 0.675509 | 4 | 0 | 4 |
| FIZ1 | FAM223B | 0.675289 | 3 | 0 | 3 |
| FIZ1 | S100A11 | 0.666832 | 4 | 0 | 3 |
| FIZ1 | EPX | 0.662577 | 3 | 0 | 3 |
| FIZ1 | CLASRP | 0.662415 | 4 | 0 | 4 |
| FIZ1 | DMWD | 0.659081 | 6 | 0 | 5 |
| FIZ1 | ZNF747 | 0.656725 | 5 | 0 | 4 |
| FIZ1 | SYT15 | 0.655939 | 4 | 0 | 4 |
| FIZ1 | ATXN2L | 0.653369 | 6 | 0 | 6 |
| FIZ1 | CIRBP-AS1 | 0.652316 | 4 | 0 | 3 |
| FIZ1 | SLC5A2 | 0.648111 | 4 | 0 | 4 |
For details and further investigation, click here
