| Full name: peroxisomal biogenesis factor 5 like | Alias Symbol: PEX5R|PXR2|TRIP8b | ||
| Type: protein-coding gene | Cytoband: 3q26.33 | ||
| Entrez ID: 51555 | HGNC ID: HGNC:30024 | Ensembl Gene: ENSG00000114757 | OMIM ID: 611058 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX5L | 51555 | 222910_s_at | 0.0631 | 0.7547 | |
| GSE20347 | PEX5L | 51555 | 219642_s_at | -0.0157 | 0.8376 | |
| GSE23400 | PEX5L | 51555 | 219642_s_at | -0.1245 | 0.0022 | |
| GSE26886 | PEX5L | 51555 | 222910_s_at | 0.0655 | 0.5917 | |
| GSE29001 | PEX5L | 51555 | 219642_s_at | -0.0732 | 0.7158 | |
| GSE38129 | PEX5L | 51555 | 219642_s_at | -0.0271 | 0.7806 | |
| GSE45670 | PEX5L | 51555 | 219642_s_at | -0.0391 | 0.5788 | |
| GSE53622 | PEX5L | 51555 | 17514 | 0.3168 | 0.0405 | |
| GSE53624 | PEX5L | 51555 | 17514 | 0.0484 | 0.7840 | |
| GSE63941 | PEX5L | 51555 | 222910_s_at | 0.2515 | 0.0633 | |
| GSE77861 | PEX5L | 51555 | 222910_s_at | 0.0068 | 0.9649 | |
| SRP133303 | PEX5L | 51555 | RNAseq | 0.5595 | 0.1145 | |
| SRP159526 | PEX5L | 51555 | RNAseq | 1.8415 | 0.0120 | |
| TCGA | PEX5L | 51555 | RNAseq | -0.4667 | 0.4277 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PEX5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX5L | 51555 | 25 | 0 | 5 | |
| GSE20123 | PEX5L | 51555 | 25 | 0 | 5 | |
| GSE43470 | PEX5L | 51555 | 24 | 0 | 19 | |
| GSE46452 | PEX5L | 51555 | 19 | 1 | 39 | |
| GSE47630 | PEX5L | 51555 | 27 | 2 | 11 | |
| GSE54993 | PEX5L | 51555 | 1 | 18 | 51 | |
| GSE54994 | PEX5L | 51555 | 41 | 0 | 12 | |
| GSE60625 | PEX5L | 51555 | 0 | 6 | 5 | |
| GSE74703 | PEX5L | 51555 | 20 | 0 | 16 | |
| GSE74704 | PEX5L | 51555 | 16 | 0 | 4 | |
| TCGA | PEX5L | 51555 | 78 | 0 | 18 |
Total number of gains: 276; Total number of losses: 27; Total Number of normals: 185.
Somatic mutations of PEX5L:
Generating mutation plots.
Highly correlated genes for PEX5L:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX5L | SCGB1D1 | 0.757973 | 3 | 0 | 3 |
| PEX5L | DNASE2B | 0.710879 | 3 | 0 | 3 |
| PEX5L | CIITA | 0.703251 | 4 | 0 | 4 |
| PEX5L | FIZ1 | 0.698578 | 3 | 0 | 3 |
| PEX5L | SYT13 | 0.697866 | 4 | 0 | 4 |
| PEX5L | SLC6A5 | 0.687656 | 3 | 0 | 3 |
| PEX5L | GH2 | 0.687319 | 3 | 0 | 3 |
| PEX5L | MTTP | 0.684677 | 3 | 0 | 3 |
| PEX5L | TCTE3 | 0.684471 | 3 | 0 | 3 |
| PEX5L | C2orf83 | 0.684149 | 3 | 0 | 3 |
| PEX5L | SCN11A | 0.684132 | 3 | 0 | 3 |
| PEX5L | LRTM1 | 0.684128 | 4 | 0 | 3 |
| PEX5L | DENND6B | 0.682458 | 4 | 0 | 4 |
| PEX5L | MAPK4 | 0.680164 | 3 | 0 | 3 |
| PEX5L | CYSLTR2 | 0.679836 | 3 | 0 | 3 |
| PEX5L | NNAT | 0.67627 | 4 | 0 | 4 |
| PEX5L | CBLN1 | 0.674758 | 4 | 0 | 4 |
| PEX5L | KIF5A | 0.668728 | 4 | 0 | 4 |
| PEX5L | CYP19A1 | 0.66849 | 3 | 0 | 3 |
| PEX5L | KIR2DL5A | 0.667151 | 4 | 0 | 4 |
For details and further investigation, click here
