| Full name: calcineurin binding protein 1 | Alias Symbol: KIAA0330|PPP3IN | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 23523 | HGNC ID: HGNC:24187 | Ensembl Gene: ENSG00000099991 | OMIM ID: 604251 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CABIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CABIN1 | 23523 | 37652_at | 0.1653 | 0.6405 | |
| GSE20347 | CABIN1 | 23523 | 202624_s_at | 0.1092 | 0.2397 | |
| GSE23400 | CABIN1 | 23523 | 37652_at | -0.0778 | 0.2050 | |
| GSE26886 | CABIN1 | 23523 | 37652_at | 0.7619 | 0.0000 | |
| GSE29001 | CABIN1 | 23523 | 37652_at | -0.1902 | 0.1838 | |
| GSE38129 | CABIN1 | 23523 | 37652_at | -0.0604 | 0.6734 | |
| GSE45670 | CABIN1 | 23523 | 37652_at | 0.0269 | 0.7662 | |
| GSE53622 | CABIN1 | 23523 | 42212 | 0.1571 | 0.0301 | |
| GSE53624 | CABIN1 | 23523 | 42212 | 0.4145 | 0.0000 | |
| GSE63941 | CABIN1 | 23523 | 37652_at | 0.0739 | 0.8796 | |
| GSE77861 | CABIN1 | 23523 | 37652_at | 0.2616 | 0.0834 | |
| GSE97050 | CABIN1 | 23523 | A_24_P336113 | -0.3021 | 0.2848 | |
| SRP007169 | CABIN1 | 23523 | RNAseq | 1.4453 | 0.0085 | |
| SRP008496 | CABIN1 | 23523 | RNAseq | 1.1972 | 0.0006 | |
| SRP064894 | CABIN1 | 23523 | RNAseq | 0.5619 | 0.0016 | |
| SRP133303 | CABIN1 | 23523 | RNAseq | 0.0316 | 0.8111 | |
| SRP159526 | CABIN1 | 23523 | RNAseq | 0.3056 | 0.2761 | |
| SRP193095 | CABIN1 | 23523 | RNAseq | 0.5454 | 0.0002 | |
| SRP219564 | CABIN1 | 23523 | RNAseq | 0.2105 | 0.5503 | |
| TCGA | CABIN1 | 23523 | RNAseq | -0.0611 | 0.1568 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CABIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CABIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CABIN1 | 23523 | 5 | 7 | 18 | |
| GSE20123 | CABIN1 | 23523 | 5 | 6 | 19 | |
| GSE43470 | CABIN1 | 23523 | 3 | 6 | 34 | |
| GSE46452 | CABIN1 | 23523 | 32 | 1 | 26 | |
| GSE47630 | CABIN1 | 23523 | 8 | 5 | 27 | |
| GSE54993 | CABIN1 | 23523 | 3 | 6 | 61 | |
| GSE54994 | CABIN1 | 23523 | 11 | 7 | 35 | |
| GSE60625 | CABIN1 | 23523 | 5 | 0 | 6 | |
| GSE74703 | CABIN1 | 23523 | 3 | 5 | 28 | |
| GSE74704 | CABIN1 | 23523 | 2 | 3 | 15 | |
| TCGA | CABIN1 | 23523 | 26 | 16 | 54 |
Total number of gains: 103; Total number of losses: 62; Total Number of normals: 323.
Somatic mutations of CABIN1:
Generating mutation plots.
Highly correlated genes for CABIN1:
Showing top 20/858 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CABIN1 | ZBTB22 | 0.824208 | 3 | 0 | 3 |
| CABIN1 | TBC1D25 | 0.808613 | 3 | 0 | 3 |
| CABIN1 | ZC3H18 | 0.788513 | 3 | 0 | 3 |
| CABIN1 | SLC39A3 | 0.772363 | 3 | 0 | 3 |
| CABIN1 | KRT81 | 0.753744 | 4 | 0 | 4 |
| CABIN1 | EXOC3L1 | 0.751953 | 3 | 0 | 3 |
| CABIN1 | SSBP4 | 0.748038 | 4 | 0 | 4 |
| CABIN1 | COLEC11 | 0.745552 | 3 | 0 | 3 |
| CABIN1 | TSHZ3 | 0.743291 | 3 | 0 | 3 |
| CABIN1 | RAB1B | 0.740787 | 3 | 0 | 3 |
| CABIN1 | ALKBH6 | 0.737152 | 3 | 0 | 3 |
| CABIN1 | LENG8 | 0.735181 | 4 | 0 | 4 |
| CABIN1 | MIA3 | 0.733212 | 3 | 0 | 3 |
| CABIN1 | PI16 | 0.732403 | 3 | 0 | 3 |
| CABIN1 | FGF16 | 0.730168 | 3 | 0 | 3 |
| CABIN1 | CD200 | 0.725433 | 3 | 0 | 3 |
| CABIN1 | TRIM47 | 0.723662 | 4 | 0 | 4 |
| CABIN1 | POLR2A | 0.723528 | 5 | 0 | 5 |
| CABIN1 | MATN4 | 0.721774 | 3 | 0 | 3 |
| CABIN1 | MZF1 | 0.719823 | 4 | 0 | 3 |
For details and further investigation, click here
