GTPBP3

 

Full name: GTP binding protein 3, mitochondrial Alias Symbol: MSS1|THDF1|GTPBG3|MTGP1|FLJ14700
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 84705 HGNC ID: HGNC:14880 Ensembl Gene: ENSG00000130299 OMIM ID: 608536
Drug and gene relationship at DGIdb

 

Expression of GTPBP3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GTPBP3 84705 213835_x_at 0.1712 0.6321
GSE20347 GTPBP3 84705 213835_x_at 0.3700 0.0014
GSE23400 GTPBP3 84705 213835_x_at 0.1533 0.0001
GSE26886 GTPBP3 84705 213835_x_at 0.9984 0.0000
GSE29001 GTPBP3 84705 213835_x_at 0.0445 0.8357
GSE38129 GTPBP3 84705 213835_x_at 0.3391 0.0013
GSE45670 GTPBP3 84705 213835_x_at 0.2008 0.0766
GSE53622 GTPBP3 84705 26356 0.5005 0.0000
GSE53624 GTPBP3 84705 34320 0.5324 0.0000
GSE63941 GTPBP3 84705 213835_x_at 1.4135 0.0000
GSE77861 GTPBP3 84705 213835_x_at 0.2169 0.1475
GSE97050 GTPBP3 84705 A_23_P28068 0.4360 0.2151
SRP007169 GTPBP3 84705 RNAseq 0.1333 0.7391
SRP008496 GTPBP3 84705 RNAseq 0.5229 0.0649
SRP064894 GTPBP3 84705 RNAseq 0.5448 0.0020
SRP133303 GTPBP3 84705 RNAseq 0.2952 0.0646
SRP159526 GTPBP3 84705 RNAseq 0.7704 0.0053
SRP193095 GTPBP3 84705 RNAseq 0.4753 0.0000
SRP219564 GTPBP3 84705 RNAseq 0.7143 0.0684
TCGA GTPBP3 84705 RNAseq 0.2738 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by GTPBP3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GTPBP3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GTPBP3 84705 4 4 22
GSE20123 GTPBP3 84705 3 2 25
GSE43470 GTPBP3 84705 2 6 35
GSE46452 GTPBP3 84705 47 1 11
GSE47630 GTPBP3 84705 4 8 28
GSE54993 GTPBP3 84705 15 4 51
GSE54994 GTPBP3 84705 6 14 33
GSE60625 GTPBP3 84705 9 0 2
GSE74703 GTPBP3 84705 2 4 30
GSE74704 GTPBP3 84705 0 2 18
TCGA GTPBP3 84705 17 9 70

Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.  

 

Somatic mutations of GTPBP3:

 

Generating mutation plots.

 

Highly correlated genes for GTPBP3:

 

Showing top 20/1262 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GTPBP3CHCHD20.74021505
GTPBP3APOBEC3G0.739187303
GTPBP3RNF260.728682303
GTPBP3ITGB80.728118303
GTPBP3ZFP900.723088303
GTPBP3TMEM2160.717363303
GTPBP3XPNPEP30.709239303
GTPBP3MTBP0.70165404
GTPBP3CCDC580.69952303
GTPBP3CDK50.698653404
GTPBP3LEMD20.698172303
GTPBP3DDX110.693882807
GTPBP3CIZ10.693311505
GTPBP3PKP20.692479303
GTPBP3FIZ10.691969303
GTPBP3MRPL110.689505404
GTPBP3FANCD20.687922505
GTPBP3HNRNPF0.687789303
GTPBP3HSPA130.687476303
GTPBP3AEBP20.685455303

For details and further investigation, click here