| Full name: RAB11B, member RAS oncogene family | Alias Symbol: H-YPT3 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 9230 | HGNC ID: HGNC:9761 | Ensembl Gene: ENSG00000185236 | OMIM ID: 604198 |
| Drug and gene relationship at DGIdb | |||
RAB11B involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04152 | AMPK signaling pathway |
Expression of RAB11B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB11B | 9230 | 217793_at | 0.2071 | 0.4606 | |
| GSE20347 | RAB11B | 9230 | 217793_at | 0.0110 | 0.8910 | |
| GSE23400 | RAB11B | 9230 | 217793_at | -0.0083 | 0.8146 | |
| GSE26886 | RAB11B | 9230 | 217793_at | 0.3269 | 0.0086 | |
| GSE29001 | RAB11B | 9230 | 217793_at | -0.1832 | 0.1532 | |
| GSE38129 | RAB11B | 9230 | 217793_at | 0.0250 | 0.7844 | |
| GSE45670 | RAB11B | 9230 | 217793_at | -0.0962 | 0.2812 | |
| GSE53622 | RAB11B | 9230 | 106664 | -0.1130 | 0.0244 | |
| GSE53624 | RAB11B | 9230 | 106664 | -0.1129 | 0.0169 | |
| GSE63941 | RAB11B | 9230 | 217793_at | 0.5373 | 0.0221 | |
| GSE77861 | RAB11B | 9230 | 217793_at | -0.0350 | 0.7840 | |
| GSE97050 | RAB11B | 9230 | A_23_P67748 | 0.1490 | 0.4948 | |
| SRP007169 | RAB11B | 9230 | RNAseq | -0.5944 | 0.0796 | |
| SRP008496 | RAB11B | 9230 | RNAseq | -0.5044 | 0.0098 | |
| SRP064894 | RAB11B | 9230 | RNAseq | 0.2408 | 0.3264 | |
| SRP133303 | RAB11B | 9230 | RNAseq | -0.3351 | 0.0082 | |
| SRP159526 | RAB11B | 9230 | RNAseq | -0.1041 | 0.7090 | |
| SRP193095 | RAB11B | 9230 | RNAseq | -0.0889 | 0.6245 | |
| SRP219564 | RAB11B | 9230 | RNAseq | 0.3654 | 0.3034 | |
| TCGA | RAB11B | 9230 | RNAseq | -0.0980 | 0.0174 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAB11B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB11B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB11B | 9230 | 4 | 3 | 23 | |
| GSE20123 | RAB11B | 9230 | 3 | 2 | 25 | |
| GSE43470 | RAB11B | 9230 | 2 | 6 | 35 | |
| GSE46452 | RAB11B | 9230 | 47 | 1 | 11 | |
| GSE47630 | RAB11B | 9230 | 5 | 7 | 28 | |
| GSE54993 | RAB11B | 9230 | 16 | 3 | 51 | |
| GSE54994 | RAB11B | 9230 | 6 | 14 | 33 | |
| GSE60625 | RAB11B | 9230 | 9 | 0 | 2 | |
| GSE74703 | RAB11B | 9230 | 2 | 4 | 30 | |
| GSE74704 | RAB11B | 9230 | 0 | 2 | 18 | |
| TCGA | RAB11B | 9230 | 10 | 19 | 67 |
Total number of gains: 104; Total number of losses: 61; Total Number of normals: 323.
Somatic mutations of RAB11B:
Generating mutation plots.
Highly correlated genes for RAB11B:
Showing top 20/422 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB11B | ERI3 | 0.781455 | 3 | 0 | 3 |
| RAB11B | RHOG | 0.778422 | 3 | 0 | 3 |
| RAB11B | RAVER1 | 0.761573 | 4 | 0 | 4 |
| RAB11B | PHRF1 | 0.7573 | 3 | 0 | 3 |
| RAB11B | SRRT | 0.745066 | 3 | 0 | 3 |
| RAB11B | MLF2 | 0.742952 | 4 | 0 | 3 |
| RAB11B | SNAPC4 | 0.734497 | 3 | 0 | 3 |
| RAB11B | PTP4A3 | 0.730858 | 3 | 0 | 3 |
| RAB11B | LINGO1 | 0.726476 | 4 | 0 | 4 |
| RAB11B | SH3BP2 | 0.722892 | 3 | 0 | 3 |
| RAB11B | TPI1 | 0.721513 | 3 | 0 | 3 |
| RAB11B | METTL23 | 0.718525 | 3 | 0 | 3 |
| RAB11B | GSK3A | 0.715288 | 7 | 0 | 6 |
| RAB11B | TBC1D9B | 0.714781 | 3 | 0 | 3 |
| RAB11B | DPM2 | 0.711762 | 3 | 0 | 3 |
| RAB11B | PSME3 | 0.710087 | 3 | 0 | 3 |
| RAB11B | ATG13 | 0.705599 | 3 | 0 | 3 |
| RAB11B | PRR12 | 0.704763 | 4 | 0 | 4 |
| RAB11B | BZW2 | 0.704559 | 3 | 0 | 3 |
| RAB11B | TMEM145 | 0.70287 | 3 | 0 | 3 |
For details and further investigation, click here
