| Full name: gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 200959 | HGNC ID: HGNC:17969 | Ensembl Gene: ENSG00000183185 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
GABRR3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04727 | GABAergic synapse | |
| hsa05032 | Morphine addiction |
Expression of GABRR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GABRR3 | 200959 | 234410_at | 0.0753 | 0.6900 | |
| GSE26886 | GABRR3 | 200959 | 234410_at | 0.1439 | 0.2081 | |
| GSE45670 | GABRR3 | 200959 | 234410_at | 0.0418 | 0.6318 | |
| GSE53622 | GABRR3 | 200959 | 125575 | 0.0383 | 0.6602 | |
| GSE53624 | GABRR3 | 200959 | 125575 | -0.0702 | 0.4461 | |
| GSE63941 | GABRR3 | 200959 | 234410_at | 0.0893 | 0.4956 | |
| GSE77861 | GABRR3 | 200959 | 234410_at | -0.0272 | 0.7897 | |
| GSE97050 | GABRR3 | 200959 | A_23_P69020 | 0.1654 | 0.3701 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GABRR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GABRR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GABRR3 | 200959 | 20 | 1 | 9 | |
| GSE20123 | GABRR3 | 200959 | 19 | 1 | 10 | |
| GSE43470 | GABRR3 | 200959 | 18 | 1 | 24 | |
| GSE46452 | GABRR3 | 200959 | 12 | 7 | 40 | |
| GSE47630 | GABRR3 | 200959 | 16 | 6 | 18 | |
| GSE54993 | GABRR3 | 200959 | 2 | 5 | 63 | |
| GSE54994 | GABRR3 | 200959 | 27 | 5 | 21 | |
| GSE60625 | GABRR3 | 200959 | 0 | 6 | 5 | |
| GSE74703 | GABRR3 | 200959 | 14 | 1 | 21 | |
| GSE74704 | GABRR3 | 200959 | 14 | 1 | 5 | |
| TCGA | GABRR3 | 200959 | 51 | 10 | 35 |
Total number of gains: 193; Total number of losses: 44; Total Number of normals: 251.
Somatic mutations of GABRR3:
Generating mutation plots.
Highly correlated genes for GABRR3:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GABRR3 | OR10A7 | 0.724586 | 3 | 0 | 3 |
| GABRR3 | LINC00302 | 0.707772 | 3 | 0 | 3 |
| GABRR3 | OR1F1 | 0.698905 | 3 | 0 | 3 |
| GABRR3 | CDR2L | 0.694471 | 3 | 0 | 3 |
| GABRR3 | C19orf73 | 0.690106 | 4 | 0 | 4 |
| GABRR3 | MIIP | 0.683182 | 3 | 0 | 3 |
| GABRR3 | EVX1 | 0.677024 | 3 | 0 | 3 |
| GABRR3 | ZIC1 | 0.666393 | 3 | 0 | 3 |
| GABRR3 | GFRA2 | 0.66597 | 3 | 0 | 3 |
| GABRR3 | ODF3 | 0.656596 | 3 | 0 | 3 |
| GABRR3 | TAS2R39 | 0.654616 | 4 | 0 | 3 |
| GABRR3 | PGP | 0.627973 | 4 | 0 | 3 |
| GABRR3 | TEKT2 | 0.60808 | 4 | 0 | 3 |
| GABRR3 | OR2Y1 | 0.600022 | 4 | 0 | 3 |
| GABRR3 | PQBP1 | 0.591542 | 3 | 0 | 3 |
| GABRR3 | TRIM31 | 0.587928 | 4 | 0 | 3 |
| GABRR3 | BPIFB4 | 0.579775 | 5 | 0 | 3 |
| GABRR3 | NPEPL1 | 0.575143 | 4 | 0 | 3 |
| GABRR3 | C12orf54 | 0.565004 | 4 | 0 | 3 |
| GABRR3 | SRD5A2 | 0.538974 | 6 | 0 | 3 |
For details and further investigation, click here
