| Full name: aminopeptidase like 1 | Alias Symbol: FLJ11583|bA261P9.2 | ||
| Type: protein-coding gene | Cytoband: 20q13.32 | ||
| Entrez ID: 79716 | HGNC ID: HGNC:16244 | Ensembl Gene: ENSG00000215440 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NPEPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPEPL1 | 79716 | 235033_at | 0.7308 | 0.3467 | |
| GSE20347 | NPEPL1 | 79716 | 89476_r_at | -0.1778 | 0.0214 | |
| GSE23400 | NPEPL1 | 79716 | 89476_r_at | -0.1381 | 0.0002 | |
| GSE26886 | NPEPL1 | 79716 | 89476_r_at | 0.4171 | 0.0091 | |
| GSE29001 | NPEPL1 | 79716 | 89476_r_at | -0.3023 | 0.0724 | |
| GSE38129 | NPEPL1 | 79716 | 89476_r_at | -0.2750 | 0.0419 | |
| GSE45670 | NPEPL1 | 79716 | 89476_r_at | -0.0563 | 0.5588 | |
| GSE53622 | NPEPL1 | 79716 | 61509 | -0.3900 | 0.0000 | |
| GSE53624 | NPEPL1 | 79716 | 61509 | -0.1869 | 0.0181 | |
| GSE63941 | NPEPL1 | 79716 | 89476_r_at | 0.3901 | 0.0254 | |
| GSE77861 | NPEPL1 | 79716 | 89476_r_at | -0.2162 | 0.1902 | |
| GSE97050 | NPEPL1 | 79716 | A_33_P3332865 | -0.1273 | 0.5337 | |
| SRP064894 | NPEPL1 | 79716 | RNAseq | 0.1668 | 0.4751 | |
| SRP133303 | NPEPL1 | 79716 | RNAseq | -0.1159 | 0.5344 | |
| SRP159526 | NPEPL1 | 79716 | RNAseq | -0.2680 | 0.2508 | |
| SRP193095 | NPEPL1 | 79716 | RNAseq | 0.1277 | 0.3848 | |
| SRP219564 | NPEPL1 | 79716 | RNAseq | 0.2928 | 0.5792 | |
| TCGA | NPEPL1 | 79716 | RNAseq | -0.0039 | 0.9407 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NPEPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPEPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPEPL1 | 79716 | 14 | 2 | 14 | |
| GSE20123 | NPEPL1 | 79716 | 14 | 2 | 14 | |
| GSE43470 | NPEPL1 | 79716 | 13 | 0 | 30 | |
| GSE46452 | NPEPL1 | 79716 | 29 | 0 | 30 | |
| GSE47630 | NPEPL1 | 79716 | 24 | 1 | 15 | |
| GSE54993 | NPEPL1 | 79716 | 0 | 17 | 53 | |
| GSE54994 | NPEPL1 | 79716 | 29 | 0 | 24 | |
| GSE60625 | NPEPL1 | 79716 | 0 | 0 | 11 | |
| GSE74703 | NPEPL1 | 79716 | 11 | 0 | 25 | |
| GSE74704 | NPEPL1 | 79716 | 11 | 0 | 9 | |
| TCGA | NPEPL1 | 79716 | 43 | 4 | 49 |
Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.
Somatic mutations of NPEPL1:
Generating mutation plots.
Highly correlated genes for NPEPL1:
Showing top 20/587 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPEPL1 | TMEM179 | 0.811813 | 3 | 0 | 3 |
| NPEPL1 | JSRP1 | 0.807182 | 4 | 0 | 4 |
| NPEPL1 | LENG1 | 0.801835 | 3 | 0 | 3 |
| NPEPL1 | LRFN2 | 0.797821 | 3 | 0 | 3 |
| NPEPL1 | ARMC5 | 0.768295 | 4 | 0 | 4 |
| NPEPL1 | ARHGAP30 | 0.757275 | 4 | 0 | 3 |
| NPEPL1 | TM6SF2 | 0.738722 | 5 | 0 | 5 |
| NPEPL1 | RIMS4 | 0.73832 | 4 | 0 | 3 |
| NPEPL1 | REG3A | 0.736863 | 5 | 0 | 5 |
| NPEPL1 | ADAMTS7 | 0.735033 | 6 | 0 | 6 |
| NPEPL1 | NRG1 | 0.73261 | 5 | 0 | 5 |
| NPEPL1 | CHRD | 0.730651 | 4 | 0 | 4 |
| NPEPL1 | C11orf86 | 0.725343 | 4 | 0 | 4 |
| NPEPL1 | RNF151 | 0.723939 | 4 | 0 | 4 |
| NPEPL1 | GPR78 | 0.722196 | 3 | 0 | 3 |
| NPEPL1 | AMN | 0.721385 | 7 | 0 | 6 |
| NPEPL1 | TOR2A | 0.720479 | 4 | 0 | 4 |
| NPEPL1 | FAM99B | 0.716261 | 3 | 0 | 3 |
| NPEPL1 | DUSP15 | 0.71583 | 5 | 0 | 4 |
| NPEPL1 | SLC6A18 | 0.714428 | 4 | 0 | 3 |
For details and further investigation, click here
