C12orf54

 

Full name: chromosome 12 open reading frame 54 Alias Symbol: MGC35033
Type: protein-coding gene Cytoband: 12q13.11
Entrez ID: 121273 HGNC ID: HGNC:28553 Ensembl Gene: ENSG00000177627 OMIM ID: 

 

Expression of C12orf54:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C12orf54 121273 240353_s_at 0.9805 0.4770
GSE26886 C12orf54 121273 240353_s_at 0.0587 0.9105
GSE45670 C12orf54 121273 240353_s_at 1.0400 0.0048
GSE53622 C12orf54 121273 52901 0.4545 0.0587
GSE53624 C12orf54 121273 52901 0.3180 0.0536
GSE63941 C12orf54 121273 237701_at 0.3794 0.1728
GSE77861 C12orf54 121273 237701_at -0.1348 0.4807
GSE97050 C12orf54 121273 A_23_P405878 0.4738 0.1818
SRP133303 C12orf54 121273 RNAseq 1.6838 0.0062
SRP159526 C12orf54 121273 RNAseq -0.5037 0.3368
SRP219564 C12orf54 121273 RNAseq -0.1111 0.8887
TCGA C12orf54 121273 RNAseq 2.9303 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by C12orf54 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C12orf54:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C12orf54 121273 6 1 23
GSE20123 C12orf54 121273 6 1 23
GSE43470 C12orf54 121273 3 1 39
GSE46452 C12orf54 121273 8 1 50
GSE47630 C12orf54 121273 11 2 27
GSE54993 C12orf54 121273 0 5 65
GSE54994 C12orf54 121273 6 1 46
GSE60625 C12orf54 121273 0 0 11
GSE74703 C12orf54 121273 3 1 32
GSE74704 C12orf54 121273 4 1 15
TCGA C12orf54 121273 15 12 69

Total number of gains: 62; Total number of losses: 26; Total Number of normals: 400.  


 

Somatic mutations of C12orf54:

 

Generating mutation plots.

 

Highly correlated genes for C12orf54:

 

Showing top 20/30 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C12orf54FAM24B0.70089303
C12orf54CBX80.695149303
C12orf54SCGB1A10.656007403
C12orf54ATG4D0.648748403
C12orf54EDARADD0.643197403
C12orf54SUN50.640412303
C12orf54CYP4Z10.634592403
C12orf54HRK0.630132504
C12orf54PMCH0.61839303
C12orf54PTPRH0.600982403
C12orf54ERMP10.600687303
C12orf54ABRACL0.596517303
C12orf54PPP2R5D0.577478303
C12orf54STEAP30.570893503
C12orf54LRFN40.570844403
C12orf54GABRR30.565004403
C12orf54PTGES0.554672403
C12orf54RHBDL10.554255403
C12orf54PRICKLE30.551355403
C12orf54MMP130.54644303

For details and further investigation, click here