CDR2L

 

Full name: cerebellar degeneration related protein 2 like Alias Symbol: HUMPPA
Type: protein-coding gene Cytoband: 17q25.1
Entrez ID: 30850 HGNC ID: HGNC:29999 Ensembl Gene: ENSG00000109089 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CDR2L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDR2L 30850 213230_at 0.7340 0.1391
GSE20347 CDR2L 30850 213230_at 0.3893 0.0045
GSE23400 CDR2L 30850 213230_at 0.1668 0.0043
GSE26886 CDR2L 30850 213230_at 0.4539 0.0367
GSE29001 CDR2L 30850 213230_at 0.2950 0.4749
GSE38129 CDR2L 30850 213230_at 0.2594 0.0566
GSE45670 CDR2L 30850 213230_at 0.2128 0.2789
GSE53622 CDR2L 30850 13684 0.2559 0.0053
GSE53624 CDR2L 30850 13684 -1.1106 0.0000
GSE63941 CDR2L 30850 213230_at -0.5231 0.3883
GSE77861 CDR2L 30850 213230_at 0.1413 0.4558
GSE97050 CDR2L 30850 A_33_P3352712 0.1016 0.7244
SRP007169 CDR2L 30850 RNAseq 0.9395 0.0944
SRP008496 CDR2L 30850 RNAseq 1.2853 0.0035
SRP064894 CDR2L 30850 RNAseq 0.8036 0.0000
SRP133303 CDR2L 30850 RNAseq 1.4924 0.0000
SRP159526 CDR2L 30850 RNAseq 0.9860 0.0014
SRP193095 CDR2L 30850 RNAseq 0.4376 0.1352
SRP219564 CDR2L 30850 RNAseq 1.0045 0.0394
TCGA CDR2L 30850 RNAseq -0.2098 0.0044

Upregulated datasets: 3; Downregulated datasets: 1.  

 

Survival by CDR2L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CDR2L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDR2L 30850 6 2 22
GSE20123 CDR2L 30850 6 2 22
GSE43470 CDR2L 30850 5 3 35
GSE46452 CDR2L 30850 33 0 26
GSE47630 CDR2L 30850 8 1 31
GSE54993 CDR2L 30850 2 5 63
GSE54994 CDR2L 30850 10 4 39
GSE60625 CDR2L 30850 6 0 5
GSE74703 CDR2L 30850 5 1 30
GSE74704 CDR2L 30850 4 1 15
TCGA CDR2L 30850 32 10 54

Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.  

 

Somatic mutations of CDR2L:

 

Generating mutation plots.

 

Highly correlated genes for CDR2L:

 

Showing top 20/146 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDR2LSPRED30.795825303
CDR2LMAPK8IP20.77351303
CDR2LFAM181B0.724309303
CDR2LTMEM59L0.703592303
CDR2LSCN2B0.69455303
CDR2LGABRR30.694471303
CDR2LMOK0.689414303
CDR2LRIMBP20.674797303
CDR2LTBCCD10.669352404
CDR2LLRRC460.669089404
CDR2LSHISA40.668984505
CDR2LPRR70.665052706
CDR2LSRCAP0.664467504
CDR2LCPLX20.662832303
CDR2LJRKL0.661934303
CDR2LADAMTS70.661285303
CDR2LC1QL10.658723303
CDR2LALPL0.658402303
CDR2LHES50.656718404
CDR2LHK30.656222403

For details and further investigation, click here