| Full name: gamma-glutamyltransferase 6 | Alias Symbol: FLJ90165 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 124975 | HGNC ID: HGNC:26891 | Ensembl Gene: ENSG00000167741 | OMIM ID: 612341 |
| Drug and gene relationship at DGIdb | |||
Expression of GGT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGT6 | 124975 | 236225_at | -1.3199 | 0.0872 | |
| GSE26886 | GGT6 | 124975 | 236225_at | -1.5716 | 0.0002 | |
| GSE45670 | GGT6 | 124975 | 236225_at | -0.8282 | 0.0210 | |
| GSE53622 | GGT6 | 124975 | 25810 | -0.8614 | 0.0000 | |
| GSE53624 | GGT6 | 124975 | 25810 | -1.3568 | 0.0000 | |
| GSE63941 | GGT6 | 124975 | 236225_at | 1.1940 | 0.0920 | |
| GSE77861 | GGT6 | 124975 | 236225_at | -1.8567 | 0.0064 | |
| GSE97050 | GGT6 | 124975 | A_23_P66767 | -0.2195 | 0.5060 | |
| SRP007169 | GGT6 | 124975 | RNAseq | -3.1953 | 0.0000 | |
| SRP008496 | GGT6 | 124975 | RNAseq | -3.6916 | 0.0000 | |
| SRP064894 | GGT6 | 124975 | RNAseq | -2.7770 | 0.0000 | |
| SRP133303 | GGT6 | 124975 | RNAseq | -2.2541 | 0.0000 | |
| SRP159526 | GGT6 | 124975 | RNAseq | -2.7913 | 0.0000 | |
| SRP193095 | GGT6 | 124975 | RNAseq | -2.1622 | 0.0000 | |
| SRP219564 | GGT6 | 124975 | RNAseq | -3.0785 | 0.0042 | |
| TCGA | GGT6 | 124975 | RNAseq | -0.5369 | 0.0783 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by GGT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GGT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGT6 | 124975 | 5 | 2 | 23 | |
| GSE20123 | GGT6 | 124975 | 5 | 3 | 22 | |
| GSE43470 | GGT6 | 124975 | 1 | 6 | 36 | |
| GSE46452 | GGT6 | 124975 | 34 | 1 | 24 | |
| GSE47630 | GGT6 | 124975 | 7 | 1 | 32 | |
| GSE54993 | GGT6 | 124975 | 4 | 3 | 63 | |
| GSE54994 | GGT6 | 124975 | 5 | 9 | 39 | |
| GSE60625 | GGT6 | 124975 | 4 | 0 | 7 | |
| GSE74703 | GGT6 | 124975 | 1 | 3 | 32 | |
| GSE74704 | GGT6 | 124975 | 3 | 1 | 16 | |
| TCGA | GGT6 | 124975 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of GGT6:
Generating mutation plots.
Highly correlated genes for GGT6:
Showing top 20/792 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGT6 | FAM163B | 0.879293 | 3 | 0 | 3 |
| GGT6 | MFSD2B | 0.864921 | 3 | 0 | 3 |
| GGT6 | TEN1 | 0.861024 | 3 | 0 | 3 |
| GGT6 | KRT78 | 0.845252 | 6 | 0 | 6 |
| GGT6 | KRTAP20-1 | 0.83407 | 3 | 0 | 3 |
| GGT6 | CD164L2 | 0.826872 | 3 | 0 | 3 |
| GGT6 | OR10G8 | 0.826579 | 3 | 0 | 3 |
| GGT6 | SNORA68 | 0.82127 | 4 | 0 | 4 |
| GGT6 | MUC22 | 0.818502 | 3 | 0 | 3 |
| GGT6 | SLC13A4 | 0.815624 | 7 | 0 | 7 |
| GGT6 | SASH1 | 0.81556 | 6 | 0 | 6 |
| GGT6 | C5orf66-AS1 | 0.81292 | 6 | 0 | 6 |
| GGT6 | EBP | 0.806252 | 3 | 0 | 3 |
| GGT6 | TP53I3 | 0.805984 | 6 | 0 | 6 |
| GGT6 | OR2Z1 | 0.804455 | 3 | 0 | 3 |
| GGT6 | ATG9B | 0.800746 | 6 | 0 | 6 |
| GGT6 | ESPL1 | 0.797662 | 7 | 0 | 7 |
| GGT6 | EPS8L2 | 0.795113 | 8 | 0 | 7 |
| GGT6 | UBL3 | 0.794665 | 6 | 0 | 6 |
| GGT6 | TCP11L2 | 0.7943 | 4 | 0 | 4 |
For details and further investigation, click here
