| Full name: t-complex 11 like 2 | Alias Symbol: MGC40368 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 255394 | HGNC ID: HGNC:28627 | Ensembl Gene: ENSG00000166046 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TCP11L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCP11L2 | 255394 | 1569206_at | -0.4624 | 0.1604 | |
| GSE26886 | TCP11L2 | 255394 | 1569206_at | -0.7219 | 0.0420 | |
| GSE45670 | TCP11L2 | 255394 | 1553861_at | -1.6912 | 0.0038 | |
| GSE53622 | TCP11L2 | 255394 | 91134 | -2.1381 | 0.0000 | |
| GSE53624 | TCP11L2 | 255394 | 91134 | -2.4259 | 0.0000 | |
| GSE63941 | TCP11L2 | 255394 | 1569206_at | 0.0369 | 0.8940 | |
| GSE77861 | TCP11L2 | 255394 | 1569206_at | -0.1864 | 0.4265 | |
| GSE97050 | TCP11L2 | 255394 | A_23_P419107 | -1.0444 | 0.0736 | |
| SRP007169 | TCP11L2 | 255394 | RNAseq | -4.3397 | 0.0000 | |
| SRP008496 | TCP11L2 | 255394 | RNAseq | -4.0726 | 0.0000 | |
| SRP064894 | TCP11L2 | 255394 | RNAseq | -3.3717 | 0.0000 | |
| SRP133303 | TCP11L2 | 255394 | RNAseq | -2.3054 | 0.0000 | |
| SRP159526 | TCP11L2 | 255394 | RNAseq | -2.3401 | 0.0000 | |
| SRP193095 | TCP11L2 | 255394 | RNAseq | -3.0939 | 0.0000 | |
| SRP219564 | TCP11L2 | 255394 | RNAseq | -3.0358 | 0.0001 | |
| TCGA | TCP11L2 | 255394 | RNAseq | -0.4507 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by TCP11L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCP11L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCP11L2 | 255394 | 5 | 3 | 22 | |
| GSE20123 | TCP11L2 | 255394 | 5 | 3 | 22 | |
| GSE43470 | TCP11L2 | 255394 | 2 | 1 | 40 | |
| GSE46452 | TCP11L2 | 255394 | 9 | 1 | 49 | |
| GSE47630 | TCP11L2 | 255394 | 9 | 1 | 30 | |
| GSE54993 | TCP11L2 | 255394 | 0 | 5 | 65 | |
| GSE54994 | TCP11L2 | 255394 | 4 | 2 | 47 | |
| GSE60625 | TCP11L2 | 255394 | 0 | 0 | 11 | |
| GSE74703 | TCP11L2 | 255394 | 2 | 0 | 34 | |
| GSE74704 | TCP11L2 | 255394 | 2 | 2 | 16 | |
| TCGA | TCP11L2 | 255394 | 21 | 9 | 66 |
Total number of gains: 59; Total number of losses: 27; Total Number of normals: 402.
Somatic mutations of TCP11L2:
Generating mutation plots.
Highly correlated genes for TCP11L2:
Showing top 20/1161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCP11L2 | PHACTR4 | 0.878275 | 5 | 0 | 5 |
| TCP11L2 | CHP1 | 0.868887 | 4 | 0 | 4 |
| TCP11L2 | ST3GAL4 | 0.822947 | 4 | 0 | 4 |
| TCP11L2 | GYS2 | 0.811553 | 5 | 0 | 5 |
| TCP11L2 | HCG22 | 0.809114 | 5 | 0 | 5 |
| TCP11L2 | MAPK3 | 0.807636 | 6 | 0 | 6 |
| TCP11L2 | KRT78 | 0.805558 | 6 | 0 | 5 |
| TCP11L2 | CPNE3 | 0.799032 | 4 | 0 | 4 |
| TCP11L2 | ENDOU | 0.798883 | 6 | 0 | 5 |
| TCP11L2 | SLC7A4 | 0.798817 | 3 | 0 | 3 |
| TCP11L2 | CRISP3 | 0.798388 | 6 | 0 | 5 |
| TCP11L2 | ALDH9A1 | 0.797402 | 5 | 0 | 5 |
| TCP11L2 | ATG9B | 0.794343 | 6 | 0 | 6 |
| TCP11L2 | GGT6 | 0.7943 | 4 | 0 | 4 |
| TCP11L2 | ANXA9 | 0.791828 | 6 | 0 | 6 |
| TCP11L2 | ASPG | 0.790094 | 5 | 0 | 5 |
| TCP11L2 | FAM3D | 0.790028 | 6 | 0 | 5 |
| TCP11L2 | TTC9 | 0.786954 | 6 | 0 | 6 |
| TCP11L2 | EMP1 | 0.782226 | 6 | 0 | 5 |
| TCP11L2 | UPK3B | 0.780349 | 3 | 0 | 3 |
For details and further investigation, click here
