| Full name: SAM and SH3 domain containing 1 | Alias Symbol: KIAA0790|dJ323M4.1|SH3D6A | ||
| Type: protein-coding gene | Cytoband: 6q24.3-q25.1 | ||
| Entrez ID: 23328 | HGNC ID: HGNC:19182 | Ensembl Gene: ENSG00000111961 | OMIM ID: 607955 |
| Drug and gene relationship at DGIdb | |||
Expression of SASH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SASH1 | 23328 | 226022_at | -1.8032 | 0.0195 | |
| GSE20347 | SASH1 | 23328 | 41644_at | -2.4624 | 0.0000 | |
| GSE23400 | SASH1 | 23328 | 41644_at | -1.6671 | 0.0000 | |
| GSE26886 | SASH1 | 23328 | 226022_at | -4.3450 | 0.0000 | |
| GSE29001 | SASH1 | 23328 | 41644_at | -2.2449 | 0.0000 | |
| GSE38129 | SASH1 | 23328 | 41644_at | -2.2013 | 0.0000 | |
| GSE45670 | SASH1 | 23328 | 226022_at | -1.4134 | 0.0036 | |
| GSE53622 | SASH1 | 23328 | 64931 | -2.9632 | 0.0000 | |
| GSE53624 | SASH1 | 23328 | 63974 | -3.2713 | 0.0000 | |
| GSE63941 | SASH1 | 23328 | 226022_at | -2.7503 | 0.0016 | |
| GSE77861 | SASH1 | 23328 | 226022_at | -2.6594 | 0.0013 | |
| GSE97050 | SASH1 | 23328 | A_33_P3209279 | -1.0424 | 0.1049 | |
| SRP007169 | SASH1 | 23328 | RNAseq | -3.7037 | 0.0000 | |
| SRP008496 | SASH1 | 23328 | RNAseq | -3.3733 | 0.0000 | |
| SRP064894 | SASH1 | 23328 | RNAseq | -2.9135 | 0.0000 | |
| SRP133303 | SASH1 | 23328 | RNAseq | -2.6319 | 0.0000 | |
| SRP159526 | SASH1 | 23328 | RNAseq | -3.2655 | 0.0000 | |
| SRP193095 | SASH1 | 23328 | RNAseq | -3.4040 | 0.0000 | |
| SRP219564 | SASH1 | 23328 | RNAseq | -2.7140 | 0.0000 | |
| TCGA | SASH1 | 23328 | RNAseq | -0.4387 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 18.
Survival by SASH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SASH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SASH1 | 23328 | 2 | 4 | 24 | |
| GSE20123 | SASH1 | 23328 | 2 | 3 | 25 | |
| GSE43470 | SASH1 | 23328 | 4 | 0 | 39 | |
| GSE46452 | SASH1 | 23328 | 3 | 10 | 46 | |
| GSE47630 | SASH1 | 23328 | 9 | 4 | 27 | |
| GSE54993 | SASH1 | 23328 | 3 | 2 | 65 | |
| GSE54994 | SASH1 | 23328 | 8 | 8 | 37 | |
| GSE60625 | SASH1 | 23328 | 0 | 1 | 10 | |
| GSE74703 | SASH1 | 23328 | 4 | 0 | 32 | |
| GSE74704 | SASH1 | 23328 | 1 | 1 | 18 | |
| TCGA | SASH1 | 23328 | 13 | 20 | 63 |
Total number of gains: 49; Total number of losses: 53; Total Number of normals: 386.
Somatic mutations of SASH1:
Generating mutation plots.
Highly correlated genes for SASH1:
Showing top 20/1736 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SASH1 | CRISP3 | 0.90674 | 11 | 0 | 11 |
| SASH1 | ABLIM1 | 0.900481 | 11 | 0 | 11 |
| SASH1 | ENDOU | 0.899373 | 11 | 0 | 11 |
| SASH1 | CYSRT1 | 0.897917 | 6 | 0 | 6 |
| SASH1 | RANBP9 | 0.887152 | 11 | 0 | 11 |
| SASH1 | GYS2 | 0.882591 | 10 | 0 | 10 |
| SASH1 | ANXA9 | 0.881052 | 11 | 0 | 11 |
| SASH1 | SNORA68 | 0.876642 | 4 | 0 | 4 |
| SASH1 | SMIM5 | 0.875541 | 6 | 0 | 6 |
| SASH1 | HPGD | 0.874772 | 11 | 0 | 11 |
| SASH1 | SLC16A6 | 0.871808 | 11 | 0 | 11 |
| SASH1 | KRT78 | 0.869233 | 8 | 0 | 8 |
| SASH1 | PRSS27 | 0.868893 | 7 | 0 | 7 |
| SASH1 | C18orf25 | 0.86841 | 11 | 0 | 11 |
| SASH1 | SIM2 | 0.866565 | 11 | 0 | 11 |
| SASH1 | FAM3B | 0.862049 | 6 | 0 | 6 |
| SASH1 | CXCR2 | 0.860391 | 11 | 0 | 11 |
| SASH1 | UBL3 | 0.859684 | 12 | 0 | 11 |
| SASH1 | MAPK3 | 0.859338 | 11 | 0 | 11 |
| SASH1 | MGLL | 0.857523 | 12 | 0 | 12 |
For details and further investigation, click here
